Reviewed, UniProtKB/Swiss-Prot Q83AB0 (ACYP_COXBU)

Names and origin

Protein names

Recommended name:
    Acylphosphatase
    EC=3.6.1.7
Alternative name(s):
    Acylphosphate phosphohydrolase

Gene names

Name:	acyP
Ordered Locus Names:	CBU_1995

Organism

Coxiella burnetii [Complete proteome] [HAMAP]

Taxonomic identifier

777 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Legionellales › Coxiellaceae › Coxiella

Protein attributes

Sequence length	95 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	An acylphosphate + H2O = a carboxylate + phosphate. HAMAP MF_01450
Sequence similarities	Belongs to the acylphosphatase family. Contains 1 acylphosphatase-like domain.

Ontologies

Keywords
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	acylphosphatase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 95	95	Acylphosphatase HAMAP MF_01450		PRO_0000326693
Regions
	Domain	10 – 95	86	Acylphosphatase-like
Sites
	Active site	25	1	By similarity
	Active site	43	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q83AB0-1 [UniParc]. Last modified April 8, 2008. Version 2. Checksum: 8C719D0EB45DD768	FASTA	95	10,908
	10 20 30 40 50 60 MTQKEKNETC IHVTVSGKVQ GVFFRESVRK KAEELQLTGW VKNLSHGDVE LVACGERDSI 70 80 90 MILTEWLWEG PPQAAVSNVN WEEIVVEDYS DFRVR

References

[1]

"Complete genome sequence of the Q-fever pathogen, Coxiella burnetii." Seshadri R., Paulsen I.T., Eisen J.A., Read T.D., Nelson K.E., Nelson W.C., Ward N.L., Tettelin H., Davidsen T.M., Beanan M.J., DeBoy R.T., Daugherty S.C., Brinkac L.M., Madupu R., Dodson R.J., Khouri H.M., Lee K.H., Carty H.A. , Scanlan D., Heinzen R.A., Thompson H.A., Samuel J.E., Fraser C.M., Heidelberg J.F. Proc. Natl. Acad. Sci. U.S.A. 100:5455-5460(2003) [PubMed: 12704232] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Nine Mile phase I / RSA 493.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE016828 Genomic DNA. Translation: AAO91484.2.
RefSeq	NP_820970.2.
3D structure databases
HSSP	HSSP built from PDB template 2ACY based on UniProtKB P41500.
ModBase	Search...
Genome annotation databases
GeneID	1209908.
GenomeReviews	Gene locus CBU_1995 in contig AE016828_GR.
KEGG	cbu:CBU_1995.
NMPDR	fig|227377.1.peg.1914.
TIGR	CBU_1995.
Phylogenomic databases
HOGENOM	Q83AB0.
Enzyme and pathway databases
BioCyc	CBUR227377:CBU_1995-MON.
BRENDA	3.6.1.7. 256353.
Family and domain databases
HAMAP	MF_01450. [Tree]
InterPro	IPR020456. Acylphosphatase. IPR001792. Acylphosphatase-like. IPR017968. Acylphosphatase_CS. [Graphical view]
PANTHER	PTHR10029. Acylphosphatase. 1 hit.
Pfam	PF00708. Acylphosphatase. 1 hit. [Graphical view]
PRINTS	PR00112. ACYLPHPHTASE.
ProDom	PD001884. Acylphosphatase. 1 hit. [Graphical view] [Entries sharing at least one domain]
PROSITE	PS00150. ACYLPHOSPHATASE_1. 1 hit. PS00151. ACYLPHOSPHATASE_2. 1 hit. PS51160. ACYLPHOSPHATASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACYP_COXBU

Accession

Primary (citable) accession number: Q83AB0

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 8, 2008
Last sequence update:	April 8, 2008
Last modified:	July 28, 2009
This is version 43 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)