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Q83927

- RDRP_OCSVU

UniProt

Q83927 - RDRP_OCSVU

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Protein
RNA-directed RNA polymerase
Gene
ORF1
Organism
Oat chlorotic stunt virus (isolate United Kingdom) (OCSV)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

RNA-dependent RNA polymerase that plays an essential role in the virus replication Reviewed prediction.

Catalytic activityi

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).

GO - Molecular functioni

  1. RNA binding Source: InterPro
  2. RNA-directed RNA polymerase activity Source: UniProtKB-KW
  3. nucleotide binding Source: UniProtKB-KW

GO - Biological processi

  1. viral RNA genome replication Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, RNA-directed RNA polymerase, Transferase

Keywords - Biological processi

Viral RNA replication

Keywords - Ligandi

Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
RNA-directed RNA polymerase (EC:2.7.7.48)
Alternative name(s):
Protein p84
Cleaved into the following chain:
Gene namesi
ORF Names:ORF1
OrganismiOat chlorotic stunt virus (isolate United Kingdom) (OCSV)
Taxonomic identifieri652110 [NCBI]
Taxonomic lineageiVirusesssRNA positive-strand viruses, no DNA stageTombusviridaeAvenavirus
Virus hostiAvena sativa (Oat) [TaxID: 4498]
ProteomesiUP000000573: Genome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 752752RNA-directed RNA polymerase
PRO_0000399490Add
BLAST
Chaini1 – 212212Protein p23
PRO_0000399491Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ83927.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini442 – 561120RdRp catalytic
Add
BLAST

Sequence similaritiesi

Family and domain databases

InterProiIPR007094. RNA-dir_pol_PSvirus.
IPR002166. RNA_pol_HCV.
[Graphical view]
PfamiPF00998. RdRP_3. 1 hit.
[Graphical view]
PROSITEiPS50507. RDRP_SSRNA_POS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q83927-1 [UniParc]FASTAAdd to Basket

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MSWPSLSGVP NGSSSVSTWL SVTHPRRSLP KELLTAFDTC NVAPEALLVL    50
RSTSLMILEE TCVVVGAAEM PTAEDNSGRE LFIGSNGDPM ERKTRTAHHA 100
IKKTVRIKKG HRTTFAMTVA NGAYVKFGAR PLTEANVLVV RKWIVKLIAD 150
EYKDLRVCDQ ALVIDRATFL SFIPTMAWNN YKFIFHGKNA VTDRVAGENL 200
FSRIAQWANP GKXGCPVVVT GQGCVISRAP DCAQLRVKRL LGVTKNRTCM 250
RVSGVSPNIQ IIPFNNDITT LERAIKERVF FVKNLDKGSP TKFVSPPRPA 300
PGVFAQRLSN TLGLLVPFLP STAPMSHQQF VDSTPSRKRK VYQQALEDIS 350
CHGLNLETDS KVKVFVKYEK TDHTSKADPV PRVISPRDPK YNLALGRYLR 400
PMEERIFKAL GKLFGHRTVM KGMDTDVTAR VIQEKWNMFN KPVAIGLDAS 450
RFDQHVSLEA LEFEHSVYLK CVRRMVDKRK LGNILRHQLL NKCYGNTPDG 500
AVSYTIEGTR MSGDMNTSLG NCVLMCMMIH AYGLHKSVNI QLANNGDDCV 550
VFLEQSDLAT FSEGLFEWFL EMGFNMAIEE PSYELEHIEF CQCRPVFDGV 600
KYTMCRNPRT AIAKDSVYLK HVDQFVTYSS WLNAVGTGGL ALAGGLPIFD 650
AFYTCYKRNS NSHWFSGRKG RLKTLSSVDD SLPWFMRELG LKGKRSSAEP 700
LPASRASFYL AWGVTPCEQL ELEKYYKSFK LDTSTLLEEH LWQPRGVFPD 750
ED 752
Length:752
Mass (Da):84,449
Last modified:November 1, 1996 - v1
Checksum:i798BB83729EC00C2
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X83964 Genomic RNA. Translation: CAA58796.1.
X83964 Genomic RNA. Translation: CAA58797.1.
RefSeqiNP_619751.1. NC_003633.1.
NP_619752.1. NC_003633.1.

Genome annotation databases

GeneIDi1732851.
940248.

Keywords - Coding sequence diversityi

RNA suppression of termination

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X83964 Genomic RNA. Translation: CAA58796.1 .
X83964 Genomic RNA. Translation: CAA58797.1 .
RefSeqi NP_619751.1. NC_003633.1.
NP_619752.1. NC_003633.1.

3D structure databases

ProteinModelPortali Q83927.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 1732851.
940248.

Family and domain databases

InterProi IPR007094. RNA-dir_pol_PSvirus.
IPR002166. RNA_pol_HCV.
[Graphical view ]
Pfami PF00998. RdRP_3. 1 hit.
[Graphical view ]
PROSITEi PS50507. RDRP_SSRNA_POS. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The nucleotide sequence and proposed genome organization of oat chlorotic stunt virus, a new soil-borne virus of cereals."
    Boonham N., Henry C.M., Wood K.R.
    J. Gen. Virol. 76:2025-2034(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Entry informationi

Entry nameiRDRP_OCSVU
AccessioniPrimary (citable) accession number: Q83927
Secondary accession number(s): Q83926
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 5, 2010
Last sequence update: November 1, 1996
Last modified: April 16, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Miscellaneous

Readthrough of the terminator UAG occurs at position 213.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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