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Q83927 (RDRP_OCSVU) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
RNA-directed RNA polymerase

EC=2.7.7.48
Alternative name(s):
Protein p84

Cleaved into the following chain:

  1. Protein p23
Gene names
ORF Names:ORF1
OrganismOat chlorotic stunt virus (isolate United Kingdom) (OCSV) [Reference proteome]
Taxonomic identifier652110 [NCBI]
Taxonomic lineageVirusesssRNA positive-strand viruses, no DNA stageTombusviridaeAvenavirus
Virus hostAvena sativa (Oat) [TaxID: 4498]

Protein attributes

Sequence length752 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

RNA-dependent RNA polymerase that plays an essential role in the virus replication Potential.

Catalytic activity

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).

Miscellaneous

Readthrough of the terminator UAG occurs at position 213.

Sequence similarities

Belongs to the tombusviridae RNA polymerase family.

Contains 1 RdRp catalytic domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 752752RNA-directed RNA polymerase
PRO_0000399490
Chain1 – 212212Protein p23
PRO_0000399491

Regions

Domain442 – 561120RdRp catalytic

Sequences

Sequence LengthMass (Da)Tools
Q83927 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 798BB83729EC00C2

FASTA75284,449
        10         20         30         40         50         60 
MSWPSLSGVP NGSSSVSTWL SVTHPRRSLP KELLTAFDTC NVAPEALLVL RSTSLMILEE 

        70         80         90        100        110        120 
TCVVVGAAEM PTAEDNSGRE LFIGSNGDPM ERKTRTAHHA IKKTVRIKKG HRTTFAMTVA 

       130        140        150        160        170        180 
NGAYVKFGAR PLTEANVLVV RKWIVKLIAD EYKDLRVCDQ ALVIDRATFL SFIPTMAWNN 

       190        200        210        220        230        240 
YKFIFHGKNA VTDRVAGENL FSRIAQWANP GKXGCPVVVT GQGCVISRAP DCAQLRVKRL 

       250        260        270        280        290        300 
LGVTKNRTCM RVSGVSPNIQ IIPFNNDITT LERAIKERVF FVKNLDKGSP TKFVSPPRPA 

       310        320        330        340        350        360 
PGVFAQRLSN TLGLLVPFLP STAPMSHQQF VDSTPSRKRK VYQQALEDIS CHGLNLETDS 

       370        380        390        400        410        420 
KVKVFVKYEK TDHTSKADPV PRVISPRDPK YNLALGRYLR PMEERIFKAL GKLFGHRTVM 

       430        440        450        460        470        480 
KGMDTDVTAR VIQEKWNMFN KPVAIGLDAS RFDQHVSLEA LEFEHSVYLK CVRRMVDKRK 

       490        500        510        520        530        540 
LGNILRHQLL NKCYGNTPDG AVSYTIEGTR MSGDMNTSLG NCVLMCMMIH AYGLHKSVNI 

       550        560        570        580        590        600 
QLANNGDDCV VFLEQSDLAT FSEGLFEWFL EMGFNMAIEE PSYELEHIEF CQCRPVFDGV 

       610        620        630        640        650        660 
KYTMCRNPRT AIAKDSVYLK HVDQFVTYSS WLNAVGTGGL ALAGGLPIFD AFYTCYKRNS 

       670        680        690        700        710        720 
NSHWFSGRKG RLKTLSSVDD SLPWFMRELG LKGKRSSAEP LPASRASFYL AWGVTPCEQL 

       730        740        750 
ELEKYYKSFK LDTSTLLEEH LWQPRGVFPD ED 

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References

[1]"The nucleotide sequence and proposed genome organization of oat chlorotic stunt virus, a new soil-borne virus of cereals."
Boonham N., Henry C.M., Wood K.R.
J. Gen. Virol. 76:2025-2034(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X83964 Genomic RNA. Translation: CAA58796.1.
X83964 Genomic RNA. Translation: CAA58797.1.
RefSeqNP_619751.1. NC_003633.1.
NP_619752.1. NC_003633.1.

3D structure databases

ProteinModelPortalQ83927.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1732851.
940248.

Family and domain databases

InterProIPR007094. RNA-dir_pol_PSvirus.
IPR002166. RNA_pol_HCV.
[Graphical view]
PfamPF00998. RdRP_3. 1 hit.
[Graphical view]
PROSITEPS50507. RDRP_SSRNA_POS. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRDRP_OCSVU
AccessionPrimary (citable) accession number: Q83927
Secondary accession number(s): Q83926
Entry history
Integrated into UniProtKB/Swiss-Prot: October 5, 2010
Last sequence update: November 1, 1996
Last modified: April 16, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families