Q836N8 (GALT_ENTFA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Galactose-1-phosphate uridylyltransferase
Short name=Gal-1-P uridylyltransferase
EC=2.7.7.12

Alternative name(s):
UDP-glucose--hexose-1-phosphate uridylyltransferase

Gene names

Name:	galT
Ordered Locus Names:	EF_1071

Organism

Enterococcus faecalis (Streptococcus faecalis)

Taxonomic identifier

1351 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Enterococcaceae › Enterococcus

Protein attributes

Sequence length	497 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	UDP-glucose + alpha-D-galactose 1-phosphate = alpha-D-glucose 1-phosphate + UDP-galactose. HAMAP MF_00571
Pathway	Carbohydrate metabolism; galactose metabolism. HAMAP MF_00571
Subcellular location	Cytoplasm Potential HAMAP MF_00571.
Sequence similarities	Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Galactose metabolism
Cellular component	Cytoplasm
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	galactose metabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	UDP-glucose:hexose-1-phosphate uridylyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 497	497	Galactose-1-phosphate uridylyltransferase HAMAP MF_00571		PRO_0000169904

Sequences

	Sequence		Length	Mass (Da)
	Q836N8 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: 8EC9C6183C7DE51C	FASTA	497	57,865
	10 20 30 40 50 60 MMKESSKWIA AFVEIIIENG DWTETDRYYL TNRIAKLVGC DFFEQPEAVA CEQEPLRVVE 70 80 90 100 110 120 HLLNIAQANH QIDDSITEAE QLEAELMDFI TPTPTIINQK FMDYYQESPR KATDYFYQLC 130 140 150 160 170 180 KTNNYIKTKA IAKNIIFPMD SPYGKLEITI NLSKPEKDAR KILAEKKMSQ KKYPACMLCM 190 200 210 220 230 240 ENEGYYGRVN YPARTNHRII RLNLEDEAWG FQYSPYAYYN EHAIFLDQQH REMKIEKKTF 250 260 270 280 290 300 QRLLKITELF PEYFVGSNAD LPIVGGSILS HDHYQAGRHT FPMDLAPMEK RFSLKKYPEI 310 320 330 340 350 360 TAGILKWPMS VIRLQSDRQE ELVEAAELIL TKWRNYSDER VSVRAYSKDG TPHHTITPIA 370 380 390 400 410 420 RRKGSLFELD LVLRDNNVSE EFPDGIFHPH PEVQHIKQEN IGLIEVMGLA ILPPRLAQEL 430 440 450 460 470 480 REVEKYLLKQ PNQIAESHRA WADELSQQTI TEANVKEVIQ QGIGTIFVQI LTDAGVFKRD 490 EEGRRAFERF IQCIEND

References

[1]

"Role of mobile DNA in the evolution of vancomycin-resistant Enterococcus faecalis." Paulsen I.T., Banerjei L., Myers G.S.A., Nelson K.E., Seshadri R., Read T.D., Fouts D.E., Eisen J.A., Gill S.R., Heidelberg J.F., Tettelin H., Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J., Daugherty S.C., DeBoy R.T., Durkin S.A. , Kolonay J.F., Madupu R., Nelson W.C., Vamathevan J.J., Tran B., Upton J., Hansen T., Shetty J., Khouri H.M., Utterback T.R., Radune D., Ketchum K.A., Dougherty B.A., Fraser C.M. Science 299:2071-2074(2003) [PubMed: 12663927] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700802 / V583.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE016830 Genomic DNA. Translation: AAO80873.1.
RefSeq	NP_814803.1. NC_004668.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1199975.
GenomeReviews	Gene locus EF_1071 in contig AE016830_GR.
KEGG	efa:EF1071.
NMPDR	fig|226185.1.peg.988.
PATRIC	21852540. VBIEntFae7065_1001.
TIGR	EF_1071.
Phylogenomic databases
HOGENOM	HBG337915.
OMA	HYFIGSN.
ProtClustDB	PRK05270.
Enzyme and pathway databases
BioCyc	EFAE226185:EF_1071-MONOMER.
Family and domain databases
HAMAP	MF_00571. GalP_UDP_trans. [Tree]
InterPro	IPR000766. GalP_uridyl_Trfase_II. IPR023425. GalP_uridyl_Trfase_II_CS. IPR005850. GalP_Utransf_C. IPR005849. GalP_Utransf_N. [Graphical view]
KO	K00965.
Pfam	PF02744. GalP_UDP_tr_C. 1 hit. PF01087. GalP_UDP_transf. 1 hit. [Graphical view]
PIRSF	PIRSF006005. GalT_BS. 1 hit.
TIGRFAMs	TIGR01239. GalT_2. 1 hit.
PROSITE	PS01163. GAL_P_UDP_TRANSF_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GALT_ENTFA

Accession

Primary (citable) accession number: Q836N8

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 4, 2003
Last sequence update:	June 1, 2003
Last modified:	January 25, 2012
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program