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Q835G1 (G6PI_ENTFA) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:EF_1416
OrganismEnterococcus faecalis (strain ATCC 700802 / V583) [Reference proteome] [HAMAP]
Taxonomic identifier226185 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliLactobacillalesEnterococcaceaeEnterococcus

Protein attributes

Sequence length449 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 449449Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_0000180639

Sites

Active site2911Proton donor By similarity
Active site3121 By similarity
Active site4261 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q835G1 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: 1DF1A5B5D483D336

FASTA44949,734
        10         20         30         40         50         60 
MSHIQLDYSK LAPFVADHEL EYMQTQVTAV DKALREGTGA GNDFTGWIDL PENYDKEEFA 

        70         80         90        100        110        120 
RIKKAAAKIQ SDSEVLVVIG IGGSYLGARA AIEFLTHSFN NLLSKEERKA PQIFFAGNSI 

       130        140        150        160        170        180 
SSTYLADLIN VIGDRDFSVN VISKSGTTTE PAIAFRVFKE LLINKYGKEE ANKRIYATTD 

       190        200        210        220        230        240 
RAKGAVKVEA DAEGWETFVI PDDVGGRFTV LTPVGLLPIA VSGADIDRLM EGANDARKEY 

       250        260        270        280        290        300 
GATSDLKENQ AYQYAALRNI LYRKGKTTEM LINYEPGMHY FSEWWKQLYG ESEGKDGKGI 

       310        320        330        340        350        360 
FPAAADFSTD LHSMGQYVQE GMRNLFETVV KIENPRHSIS IPEQNEDLDG LGYLQGKEID 

       370        380        390        400        410        420 
FVNTKAFEGT LLAHTDGGVP NMIVKVPTMD AYSLGYVMYF FEIAVGISGY LNGVNPFDQP 

       430        440 
GVEAYKRNMF ALLGKPGFEE LAKDLNARL 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE016830 Genomic DNA. Translation: AAO81207.1.
RefSeqNP_815137.1. NC_004668.1.

3D structure databases

ProteinModelPortalQ835G1.
SMRQ835G1. Positions 4-449.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING226185.EF1416.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAO81207; AAO81207; EF_1416.
GeneID1200316.
KEGGefa:EF1416.
PATRIC21853206. VBIEntFae7065_1331.

Phylogenomic databases

eggNOGCOG0166.
KOK01810.
OMAEPSLHFV.
OrthoDBEOG64R61J.
ProtClustDBPRK14097.

Enzyme and pathway databases

BioCycEFAE226185:GHI1-1403-MONOMER.
UniPathwayUPA00109; UER00181.

Family and domain databases

HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_ENTFA
AccessionPrimary (citable) accession number: Q835G1
Entry history
Integrated into UniProtKB/Swiss-Prot: March 29, 2005
Last sequence update: June 1, 2003
Last modified: February 19, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways