Putative fiber protein - Porcine adenovirus B serotype 4 (PAdV-4)

Preferred order of sections

Names and origin

Protein names	Submitted name: Putative fiber protein EMBL AAB40001.1
Organism	Porcine adenovirus B serotype 4 (PAdV-4) (Porcine adenovirus 4) EMBL AAB40001.1
Taxonomic identifier	35267 [NCBI]
Taxonomic lineage	Viruses › dsDNA viruses, no RNA stage › Adenoviridae › Mastadenovirus › Porcine adenovirus B
Virus host	Sus scrofa (Pig) [TaxID: 9823]

Protein attributes

Sequence length	703 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Technical term	3D-structure PDB 2WT1 PDB 2WT2 PDB 2WT0 PDB 2WSU PDB 2WST PDB 2WSV
Gene Ontology (GO)
Biological_process	cell adhesion Inferred from electronic annotation. Source: InterPro viral attachment to host cell Inferred from electronic annotation. Source: InterPro viral infectious cycle Inferred from electronic annotation. Source: InterPro
Molecular_function	carbohydrate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Regions

Region

435 – 439

5

Galactose binding PDB 2WT1 PDB 2WT2 PDB 2WT0

Region

459 – 462

4

Galactose binding PDB 2WT1 PDB 2WT2 PDB 2WT0

Region

585 – 586

2

Galactose binding PDB 2WT2 PDB 2WT0

Sites

Binding site

424

1

N-acetyl-D-glucosamine PDB 2WT1 PDB 2WT2

Binding site

435

1

N-acetyl-D-glucosamine PDB 2WT1

Binding site

439

1

N-acetyl-D-glucosamine PDB 2WT2 PDB 2WT0

Binding site

451

1

Galactose PDB 2WT1 PDB 2WT0

Binding site

462

1

N-acetyl-D-glucosamine PDB 2WT2 PDB 2WT0

Binding site

574

1

Galactose PDB 2WT2

Binding site

585

1

N-acetyl-D-glucosamine PDB 2WT2

Binding site

598

1

Galactose; via carbonyl oxygen PDB 2WT2

Binding site

629

1

Galactose PDB 2WT2

Sequences

Sequence

Length

Mass (Da)

Tools

Q83467 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: C2D9E7AEAEB3C0E1
Show »

FASTA

703

76,650

        10         20         30         40         50         60 
MKRSVPSDFN PVYPYDYQPI SLMPAFYDNY GFHEGPSGVL SLNIANPLGY TPRKKLCLKL 

        70         80         90        100        110        120 
GEGLALDSDG HLRVQIPDMQ AQPPLLYQGH RLSLLFDADA GFHLTEDGAL SLTKTLVYPT 

       130        140        150        160        170        180 
LWTGPAPEAN VTFSGENSPS GILRLCLSRT GGTVIGTLSV QGSLTNPSTG QTLGMNLYFD 

       190        200        210        220        230        240 
ADGNVLSESN LVRGSWGMKD QDTLVTPIAN GQYLMPNLTA YPRLIQTLTS SYIYTQAHLD 

       250        260        270        280        290        300 
HNNSVVDIKI GLNTDLRPTA AYGLSFTMTF TNSPPTSFGT DLVQFGYLGQ DSSPSFLREL 

       310        320        330        340        350        360 
PLASEAGYFG KLAAASEEMP APPEAQTQDQ AAEEPPAPAE AEAPAPAEAE AEAEPPRKPP 

       370        380        390        400        410        420 
RGDLAALYNR VHSDTRAEDT PTSPELVTTL PDPFVLPLPD GVPTGASIVL EGTLTPSAVF 

       430        440        450        460        470        480 
FTLDLVTGPA SLALHFNVRL PLEGEKHIVC NSREGSSNWG EEVRPQEFPF EREKPFVLVI 

       490        500        510        520        530        540 
VIQSDTYQIT VNGKPLVDFP QRLQGITRAS LSGDLVFTRL TMYPPGDPRP TTLLPPPAAP 

       550        560        570        580        590        600 
LDVIPDAYVL NLPTGLTPRT LLTVTGTPTP LAEFFIVNLV YDLHYDSKNV ALHFNVGFTS 

       610        620        630        640        650        660 
DSKGHIACNA RMNGTWGSEI TVSDFPFQRG KPFTLQILTR EADFQVLVDK QPLTQFQYRL 

       670        680        690        700 
KELDQIKYVH MFGHVVQTHL EHQVPDTPVF STAGVSKVYP QIL

« Hide

References

[1]	"Sequence analysis of the fiber genomic region of a porcine adenovirus predicts a novel fiber protein." Kleiboeker S.B. Virus Res. 39:299-309(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: PAV-4 EMBL AAB40001.1.
[2]	"Crystallographic structure of porcine adenovirus type 4 fiber head and galectin domains." Guardado-Calvo P., Munoz E.M., Llamas-Saiz A.L., Fox G.C., Kahn R., Curiel D.T., Glasgow J.N., van Raaij M.J. J. Virol. 84:10558-10568(2010) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.90 ANGSTROMS) OF 393-703 IN COMPLEX WITH GALACTOSE AND N-ACETYL-D-GLUCOSAMINE.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

U25120 Genomic DNA. Translation: AAB40001.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2WST	X-ray	3.20	A/B/C/D/E/F	116-291	[»]
2WSU	X-ray	1.90	A/B/C/D	393-703	[»]
2WSV	X-ray	2.00	A	393-703	[»]
2WT0	X-ray	1.91	A	393-703	[»]
2WT1	X-ray	1.90	A	393-703	[»]
2WT2	X-ray	2.50	A/B	393-703	[»]

ProteinModelPortal

Q83467.

ModBase

Search...

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Family and domain databases

Gene3D

2.10.25.20. 1 hit.
2.60.120.200. 2 hits.
2.60.90.10. 1 hit.

InterPro

IPR000931. Adeno_fibre.
IPR000978. Adeno_fibre_knob.
IPR008982. Adenovirus_pIV-rel_att.
IPR009013. Attachment_protein_shaft_dom.
IPR008985. ConA-like_lec_gl_sf.
IPR013320. ConA-like_subgrp.
IPR001079. Galectin_CRD.
[Graphical view]

Pfam

PF00541. Adeno_knob. 1 hit.
PF00337. Gal-bind_lectin. 2 hits.
[Graphical view]

PRINTS

PR00307. ADENOVSFIBRE.

SMART

SM00908. Gal-bind_lectin. 2 hits.
SM00276. GLECT. 2 hits.
[Graphical view]

SUPFAM

SSF49899. ConA_like_lec_gl. 2 hits.
SSF49835. Viral_att. 1 hit.

PROSITE

PS51304. GALECTIN. 2 hits.
[Graphical view]

ProtoNet

Search...

Other

EvolutionaryTrace

Q83467.

Entry information

Entry name

Q83467_ADEP4

Accession

Primary (citable) accession number: Q83467

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1996
Last sequence update:	November 1, 1996
Last modified:	May 1, 2013
This is version 80 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)