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Q833I9 (PGK_ENTFA) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoglycerate kinase

EC=2.7.2.3
Gene names
Name:pgk
Ordered Locus Names:EF_1963
OrganismEnterococcus faecalis (strain ATCC 700802 / V583) [Reference proteome] [HAMAP]
Taxonomic identifier226185 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliLactobacillalesEnterococcaceaeEnterococcus

Protein attributes

Sequence length397 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP-Rule MF_00145

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP-Rule MF_00145

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00145

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_00145.

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processglycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycerate kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 397397Phosphoglycerate kinase HAMAP-Rule MF_00145
PRO_0000145944

Regions

Nucleotide binding353 – 3564ATP By similarity
Region21 – 233Substrate binding By similarity
Region59 – 624Substrate binding By similarity

Sites

Binding site361Substrate By similarity
Binding site1191Substrate By similarity
Binding site1561Substrate By similarity
Binding site2071ATP By similarity
Binding site2951ATP; via carbonyl oxygen By similarity
Binding site3261ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q833I9 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: C5950AF7DE1C84ED

FASTA39742,397
        10         20         30         40         50         60 
MAKKTIKDVD LKDKKVLVRV DFNVPLKDGV ITNDNRIVAA LPTIKYVIEN GGKAILFSHL 

        70         80         90        100        110        120 
GRVKTEEDKA GKSLKPVAER LSELLGQPVT FVPETRGKEL EDAVNNMKDG DVLVFENTRF 

       130        140        150        160        170        180 
EDVDGKKESG NDAELGKYWA SLGDVFVNDA FGTAHRAHAS NVGIASTGIP TVAGFLMEKE 

       190        200        210        220        230        240 
IKFIGEAVEN PKRPFVAILG GAKVSDKIAV IENLIEKADK ILIGGGMAYT FMKAQGYSVG 

       250        260        270        280        290        300 
LSLLEEDKVD LAKSLMEKAG DKLVLPVDTV VSKEFSNDAP FHTVPSTEIP DDEEGLDIGE 

       310        320        330        340        350        360 
KTIELFANEL QGAKTVVWNG PMGVFEMSNF AKGTIGVCEA IANLEDATTI IGGGDSAAAA 

       370        380        390 
IQLGYENKFS HISTGGGASL ELLEGKTLPG LASINDK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE016830 Genomic DNA. Translation: AAO81709.1.
RefSeqNP_815639.1. NC_004668.1.

3D structure databases

ProteinModelPortalQ833I9.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING226185.EF1963.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAO81709; AAO81709; EF_1963.
GeneID1200838.
KEGGefa:EF1963.
PATRIC21854230. VBIEntFae7065_1841.

Phylogenomic databases

eggNOGCOG0126.
KOK00927.
OMAFGLADKM.
OrthoDBEOG64N9Z0.
ProtClustDBPRK00073.

Enzyme and pathway databases

BioCycEFAE226185:GHI1-1924-MONOMER.
UniPathwayUPA00109; UER00185.

Family and domain databases

Gene3D3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPMF_00145. Phosphoglyc_kinase.
InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERPTHR11406. PTHR11406. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PIRSFPIRSF000724. Pgk. 1 hit.
PRINTSPR00477. PHGLYCKINASE.
SUPFAMSSF53748. SSF53748. 1 hit.
PROSITEPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePGK_ENTFA
AccessionPrimary (citable) accession number: Q833I9
Entry history
Integrated into UniProtKB/Swiss-Prot: April 26, 2004
Last sequence update: June 1, 2003
Last modified: February 19, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways