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Q831R1 (UPPP1_ENTFA) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 79. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein
Undecaprenyl pyrophosphate phosphatase
Gene names
Name:uppP
Synonyms:bacA, upk
Ordered Locus Names:EF_2439
OrganismEnterococcus faecalis (strain ATCC 700802 / V583) [Reference proteome] [HAMAP]
Taxonomic identifier226185 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliLactobacillalesEnterococcaceaeEnterococcus

Protein attributes

Sequence length276 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 276276Undecaprenyl-diphosphatase HAMAP-Rule MF_01006
PRO_0000151149

Regions

Transmembrane45 – 6521Helical; Potential
Transmembrane85 – 10521Helical; Potential
Transmembrane113 – 13321Helical; Potential
Transmembrane150 – 17021Helical; Potential
Transmembrane188 – 20821Helical; Potential
Transmembrane225 – 24521Helical; Potential
Transmembrane255 – 27521Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q831R1 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: 29C5E1746DCB1862

FASTA27630,819
        10         20         30         40         50         60 
MLFANLWKAI ILGIIEGITE WLPISSTGHL ILVDEFIKLD LSKDFMEMFN VVIQLGAIMA 

        70         80         90        100        110        120 
VVILYFHKLN PFSPKKNGEE KKDTWILWSK VLVACLPAAV IGLKFDDYLD AHFYNFLTVS 

       130        140        150        160        170        180 
IMLIVYGIAF IIIEKRNKNV APKCTNLKDF TYKAALIVGA FQVLALIPGT SRSGATILGA 

       190        200        210        220        230        240 
ILIGASRFVA TEFSFFLGIP VMFGASFLKI FKFLAKGNTF GSEEIIILIT GSIVAFVVSI 

       250        260        270 
IAIKFLLNYL KKNDFTVFGW YRVILGAILI GYWLFS 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE016830 Genomic DNA. Translation: AAO82157.1.
RefSeqNP_816087.1. NC_004668.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING226185.EF2439.

Protocols and materials databases

DNASU1201305.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAO82157; AAO82157; EF_2439.
GeneID1201305.
KEGGefa:EF2439.
PATRIC21855113. VBIEntFae7065_2277.

Phylogenomic databases

eggNOGCOG1968.
KOK06153.
OMAMEQINIG.
OrthoDBEOG6QP13M.

Enzyme and pathway databases

BioCycEFAE226185:GHI1-2389-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
TIGRFAMsTIGR00753. undec_PP_bacA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUPPP1_ENTFA
AccessionPrimary (citable) accession number: Q831R1
Entry history
Integrated into UniProtKB/Swiss-Prot: April 13, 2004
Last sequence update: June 1, 2003
Last modified: May 14, 2014
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families