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Q831N1 (SYR_ENTFA) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 73. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:EF_2471
OrganismEnterococcus faecalis (strain ATCC 700802 / V583) [Reference proteome] [HAMAP]
Taxonomic identifier226185 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliLactobacillalesEnterococcaceaeEnterococcus

Protein attributes

Sequence length563 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 563563Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_0000151560

Regions

Motif122 – 13211"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q831N1 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: 01E69002F2987ED0

FASTA56364,154
        10         20         30         40         50         60 
MNNKEIVAKA LHDVLNEELT MDQIEQLLEN PKSVDHGDVA FPAFSLAKIY RKAPQQIAAE 

        70         80         90        100        110        120 
LAEKIDGTNF EKIEVVGPYL NFFMNKEAVS QAVIGEVVKE KNNYGNSTFG NNGNVPIDMS 

       130        140        150        160        170        180 
SPNIAKPISM GHLRSTVIGN SIAFILEKIG YQPIRINHLG DWGTQFGKLI VAYKKWGSEE 

       190        200        210        220        230        240 
AVRQQPINEL LRLYVQFHEE AEEKPELEDE ARAWFKKLEE GDQEANELWK WFRSESLKEF 

       250        260        270        280        290        300 
DKIYSMLEVE FDSYNGEAFY NDKMDEIVTL LEEKHLLTEN QGAEIVDLTE YNLNPALIRK 

       310        320        330        340        350        360 
SDGATLYITR DLAAALYRKR TYDFAKSLYV VGNEQSNHFK QLKAVLKELG FDWSDDMEHI 

       370        380        390        400        410        420 
PFGLITQGGK KLSTRKGKIV LLEEVLNEAV TLAGNQINEK NPDLANREEV AKQVGVGAVI 

       430        440        450        460        470        480 
FHDLKNDRLN NFDFVLDEVV RFEGETGPYV QYTHARAMSI LRKANFTPDA TQRYALNDKD 

       490        500        510        520        530        540 
SWEVVKLLQK FPETVMQAAE KYEPSVIAKH SIHLAQAFNK YYAHVRILDE DAQKEARLAL 

       550        560 
VYAVATVLKE DLRLLGLHAP EEM 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE016830 Genomic DNA. Translation: AAO82188.1.
RefSeqNP_816118.1. NC_004668.1.

3D structure databases

ProteinModelPortalQ831N1.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING226185.EF2471.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAO82188; AAO82188; EF_2471.
GeneID1201336.
KEGGefa:EF2471.
PATRIC21855175. VBIEntFae7065_2308.

Phylogenomic databases

eggNOGCOG0018.
KOK01887.
OMAYVKFHDE.
OrthoDBEOG6JB13C.

Enzyme and pathway databases

BioCycEFAE226185:GHI1-2420-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
ProtoNetSearch...

Entry information

Entry nameSYR_ENTFA
AccessionPrimary (citable) accession number: Q831N1
Entry history
Integrated into UniProtKB/Swiss-Prot: November 14, 2003
Last sequence update: June 1, 2003
Last modified: May 14, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries