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Q830Y8 (Q830Y8_ENTFA) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Nicotinate phosphoribosyltransferase RuleBase RU003838

EC=2.4.2.11 RuleBase RU003838
Gene names
Ordered Locus Names:EF_2626
OrganismEnterococcus faecalis (Streptococcus faecalis)
Taxonomic identifier1351 [NCBI]
Taxonomic lineageBacteriaFirmicutesLactobacillalesEnterococcaceaeEnterococcus

Protein attributes

Sequence length494 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

Nicotinate D-ribonucleotide + diphosphate = nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate. RuleBase RU003838 SAAS SAAS002638

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. SAAS SAAS002638

Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate ribonucleotide from nicotinate: step 1/1. RuleBase RU003838

Sequence similarities

Belongs to the NAPRTase family. RuleBase RU003838

Sequences

Sequence LengthMass (Da)Tools
Q830Y8 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: 9A7889A467B392C6

FASTA49456,582
        10         20         30         40         50         60 
MDYTYADDSL TLHTDMYQIN MMQTYWELGR ADLHAVFECY FREMPFNHGY AIFAGLERLV 

        70         80         90        100        110        120 
NYLENLTFTE SDIAYLREVE EYPEDFLTYL ANFEFKCTVR SALEGDLVFN NEPLIQIEGP 

       130        140        150        160        170        180 
LAQCQLVETA LLNMVNFQTL IATKAARIKS VIGDDPLLEF GTRRAQELDA AIWGTRAAYI 

       190        200        210        220        230        240 
GGADATSNVR AGKIFGIPVS GTHAHSLVQS YGNDYEAFMA YAKTHRDCVF LVDTYDTLKA 

       250        260        270        280        290        300 
GVPSAIRVAR EMGDKINFLG VRIDSGDMAY ISKRVREQLD EAGFTEAKIY ASNDLDENTI 

       310        320        330        340        350        360 
LNLKMQKSKI DVWGVGTKLI TAYDQPALGA VFKLVSIEGE DGQMKDTIKL SSNAEKVTTP 

       370        380        390        400        410        420 
GKKQVWRITR KSDKKSEGDY VTLWNEDPRQ EEEIYMFHPV HTFINKYVRD FEARPVLQDI 

       430        440        450        460        470        480 
FVEGKRVYEL PTLDEIKQYA KENLDSLWEE YKRDLNPQKY PVDLSTDCWN HKMNLLEKVR 

       490 
KDVKHLTETV NKEA 

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References

« Hide 'large scale' references
[1]"Role of mobile DNA in the evolution of vancomycin-resistant Enterococcus faecalis."
Paulsen I.T., Banerjei L., Myers G.S.A., Nelson K.E., Seshadri R., Read T.D., Fouts D.E., Eisen J.A., Gill S.R., Heidelberg J.F., Tettelin H., Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J., Daugherty S.C., DeBoy R.T., Durkin S.A. expand/collapse author list , Kolonay J.F., Madupu R., Nelson W.C., Vamathevan J.J., Tran B., Upton J., Hansen T., Shetty J., Khouri H.M., Utterback T.R., Radune D., Ketchum K.A., Dougherty B.A., Fraser C.M.
Science 299:2071-2074(2003) [PubMed: 12663927] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700802 / V583.
[2]"Crystal Structure of Enterococcus Faecalis Nicotinate Phosphoribosyltransferase."
Patskovsky Y., Almo S.C.
Submitted (NOV-2005) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS).

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE016830 Genomic DNA. Translation: AAO82335.1.
RefSeqNP_816265.1. NC_004668.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2F7FX-ray2.00A1-494[»]
ProteinModelPortalQ830Y8.
SMRQ830Y8. Positions 4-485.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1201485.
GenomeReviewsGene locus EF_2626 in contig AE016830_GR.
KEGGefa:EF2626.
NMPDRfig|226185.1.peg.2450.
PATRIC21855459. VBIEntFae7065_2449.
TIGREF_2626.

Phylogenomic databases

HOGENOMHBG292386.
OMAQVWRITR.
ProtClustDBPRK09243.

Family and domain databases

InterProIPR015977. Nic_PRibTrfase-like.
IPR007229. Nic_PRibTrfase-rel.
IPR006405. Nic_PRibTrfase_put.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
KOK00763.
PANTHERPTHR11098:SF1. NAPRTase. 1 hit.
PfamPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFPIRSF000484. NAPRT. 1 hit.
SUPFAMSSF51690. Q_phspho_trans. 1 hit.
TIGRFAMsTIGR01513. NAPRTase_put. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ830Y8_ENTFA
AccessionPrimary (citable) accession number: Q830Y8
Entry history
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: December 14, 2011
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)