Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q830V1 (MGTE_ENTFA) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Magnesium transporter mgtE
Gene names
Name:mgtE
Ordered Locus Names:EF_2668
OrganismEnterococcus faecalis (Streptococcus faecalis)
Taxonomic identifier1351 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Lactobacillales › Enterococcaceae › Enterococcus

Protein attributes

Sequence length453 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Acts as a magnesium transporter By similarity.

Subunit structure

Homodimer By similarity.

Subcellular location

Cell membrane; Multi-pass membrane protein Potential.

Sequence similarities

Belongs to the SLC41A transporter family.

Contains 2 CBS domains.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 453453Magnesium transporter mgtE
PRO_0000363888

Regions

Topological domain1 – 278278Cytoplasmic By similarity
Transmembrane279 – 30628Helical; Name=1; By similarity
Intramembrane307 – 32115 By similarity
Transmembrane322 – 34524Helical; Name=2; By similarity
Topological domain346 – 3527Cytoplasmic By similarity
Transmembrane353 – 38331Helical; Name=3; By similarity
Intramembrane384 – 3874 By similarity
Transmembrane388 – 41629Helical; Name=4; By similarity
Intramembrane417 – 42610 By similarity
Transmembrane427 – 44923Helical; Name=5; By similarity
Topological domain450 – 4523Periplasmic By similarity
Domain142 – 20564CBS 1
Domain206 – 26257CBS 2

Sites

Metal binding981Magnesium 1 By similarity
Metal binding1021Magnesium 2 By similarity
Metal binding2181Magnesium 3 By similarity
Metal binding2201Magnesium 4 By similarity
Metal binding2301Magnesium 5 By similarity
Metal binding2511Magnesium 1 By similarity
Metal binding2591Magnesium 3 By similarity
Metal binding2631Magnesium 4 By similarity
Metal binding4201Magnesium 4 By similarity
Metal binding4341Magnesium 6 By similarity

Secondary structure

1 .......................................... 453
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q830V1 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: CDB202115B7BD54F

FASTA45350,320
        10         20         30         40         50         60 
MNEGQEMEEQ FALLLETLKN QQMNEFRELF LALHIYEQGQ FYQSLDEKDR QHLYNYLSPK 

        70         80         90        100        110        120 
ELADMFDVIE EDNENMKDYL AEMRPSYAAD MLAEMYTDNA VDLLNMLDKS QKAKYLSLLS 

       130        140        150        160        170        180 
SEEAGEIKEL LHYEDETAGA IMTTEFVSIV ANQTVRSAMY VLKNQADMAE TIYYVYVVDQ 

       190        200        210        220        230        240 
ENHLVGVISL RDLIVNDDDT LIADILNERV ISVHVGDDQE DVAQTIRDYD FLAVPVTDYD 

       250        260        270        280        290        300 
DHLLGIVTVD DIIDVIDDEA ASDYSGLAGV DVEEVSENPL KAASKRLPWL ITLLFLGMST 

       310        320        330        340        350        360 
ASLISNYESL VSEASILAVF ISLITGTAGN AGTQSLAVAV RRLAMKDEKD SNFGRLILSE 

       370        380        390        400        410        420 
VLTGLVTGAV TGLTIMIVVG VWQHNLPLGF VIGMAMLCAI TVANLAGSLI PMLMDKLGFD 

       430        440        450 
PAVASGPFIT TLSDLTSVLI YFNIASMFMR YFV

« Hide

References

« Hide 'large scale' references
[1]"Role of mobile DNA in the evolution of vancomycin-resistant Enterococcus faecalis."
Paulsen I.T., Banerjei L., Myers G.S.A., Nelson K.E., Seshadri R., Read T.D., Fouts D.E., Eisen J.A., Gill S.R., Heidelberg J.F., Tettelin H., Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J., Daugherty S.C., DeBoy R.T., Durkin S.A. expand/collapse author list , Kolonay J.F., Madupu R., Nelson W.C., Vamathevan J.J., Tran B., Upton J., Hansen T., Shetty J., Khouri H.M., Utterback T.R., Radune D., Ketchum K.A., Dougherty B.A., Fraser C.M.
Science 299:2071-2074(2003) [PubMed: 12663927] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700802 / V583.
[2]"Crystallization and preliminary X-ray diffraction analysis of the full-length Mg2+ transporter MgtE."
Hattori M., Tanaka Y., Fukai S., Ishitani R., Nureki O.
Acta Crystallogr. F 63:682-684(2007) [PubMed: 17671367] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.16 ANGSTROMS) OF 2-285.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE016830 Genomic DNA. Translation: AAO82375.1.
RefSeqNP_816305.1. NC_004668.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2OUXX-ray2.16A/B2-285[»]
ProteinModelPortalQ830V1.
SMRQ830V1. Positions 6-262.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1201525.
GenomeReviewsGene locus EF_2668 in contig AE016830_GR.
KEGGefa:EF2668.
NMPDRfig|226185.1.peg.2490.
PATRIC21855539. VBIEntFae7065_2489.
TIGREF_2668.

Phylogenomic databases

HOGENOMHBG680933.
OMADPAIMAS.
ProtClustDBCLSK583150.

Enzyme and pathway databases

BioCycEFAE226185:EF_2668-MONOMER.

Family and domain databases

InterProIPR013785. Aldolase_TIM.
IPR000644. Cysta_beta_synth_core.
IPR006668. Mg_transptr_MgtE_intracell_dom.
IPR006667. MgtE_Mg_transptr_membr.
IPR006669. MgtE_transporter.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK06213.
PfamPF00571. CBS. 2 hits.
PF01769. MgtE. 1 hit.
PF03448. MgtE_N. 1 hit.
[Graphical view]
SMARTSM00116. CBS. 2 hits.
SM00924. MgtE_N. 1 hit.
[Graphical view]
TIGRFAMsTIGR00400. MgtE. 1 hit.
PROSITEPS51371. CBS. 2 hits.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameMGTE_ENTFA
AccessionPrimary (citable) accession number: Q830V1
Entry history
Integrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: June 1, 2003
Last modified: January 25, 2012
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents