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Q82ZQ1 (ALLB_ENTFA) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 72. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Allantoinase

EC=3.5.2.5
Alternative name(s):
Allantoin-utilizing enzyme
Gene names
Name:allB
Ordered Locus Names:EF_2999
OrganismEnterococcus faecalis (strain ATCC 700802 / V583) [Reference proteome] [HAMAP]
Taxonomic identifier226185 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliLactobacillalesEnterococcaceaeEnterococcus

Protein attributes

Sequence length454 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring By similarity. HAMAP-Rule MF_01645

Catalytic activity

(S)-allantoin + H2O = allantoate. HAMAP-Rule MF_01645

Cofactor

Binds 2 zinc ions per subunit By similarity. HAMAP-Rule MF_01645

Pathway

Nitrogen metabolism; (S)-allantoin degradation; allantoate from (S)-allantoin: step 1/1. HAMAP-Rule MF_01645

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_01645

Post-translational modification

Carbamylation allows a single lysine to coordinate two zinc ions By similarity. HAMAP-Rule MF_01645

Sequence similarities

Belongs to the DHOase family. Allantoinase subfamily.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 454454Allantoinase HAMAP-Rule MF_01645
PRO_0000317674

Sites

Metal binding581Zinc 1 By similarity
Metal binding601Zinc 1 By similarity
Metal binding1491Zinc 1; via carbamate group By similarity
Metal binding1491Zinc 2; via carbamate group By similarity
Metal binding1891Zinc 2 By similarity
Metal binding2451Zinc 2 By similarity
Metal binding3181Zinc 1 By similarity

Amino acid modifications

Modified residue1491N6-carboxylysine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q82ZQ1 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: B5E4B3F04ED062F4

FASTA45448,713
        10         20         30         40         50         60 
MQAELVIKNG LVILETGEVI TDVAVQGGKI VAIGQDLSGE RVIDATGLVV SPGMVDAHVH 

        70         80         90        100        110        120 
ITDPGGGYRD EWEGYVTGTA ACAKGGVTTF MEMPLNQIPA TVDKTSLEIK YKAGENKLKV 

       130        140        150        160        170        180 
DVGSFGGVVP TNLADGIQEL DEGGVSGYKC FLGTCGDRSI EGDFQNVDDY SLYEGMKQVA 

       190        200        210        220        230        240 
KTGKVLAIHA ENAPITDKLG AVAYQNGETT LAAYVATRPV FTEVEAIQKA ILFAKETGCR 

       250        260        270        280        290        300 
IHICHVACQE GVEEVLKAQA EGVDVTCETC THYLYFTTDE LDAIGPVVKC SPPIRDADQQ 

       310        320        330        340        350        360 
AALWNHVQTG GIAFVTSDHS PCTPDLKDTT NAFEAWGGIS GVQNNVDVLF DEAVQKRGLS 

       370        380        390        400        410        420 
LKQFADMIAA NPADRYHLAQ KGRISIGKDA DFVLIKPNAP YILKAEDLEY RNKISPYIGR 

       430        440        450 
EIGAQVIQTI LRGETIYAQE TGVTEAFNGV FIKN 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE016830 Genomic DNA. Translation: AAO82684.1.
RefSeqNP_816614.1. NC_004668.1.

3D structure databases

ProteinModelPortalQ82ZQ1.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING226185.EF2999.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAO82684; AAO82684; EF_2999.
GeneID1201848.
KEGGefa:EF2999.
PATRIC21856167. VBIEntFae7065_2796.

Phylogenomic databases

eggNOGCOG0044.
KOK01466.
OMAFREPGHT.
OrthoDBEOG6KHFW6.

Enzyme and pathway databases

BioCycEFAE226185:GHI1-2930-MONOMER.
UniPathwayUPA00395; UER00653.

Family and domain databases

Gene3D2.30.40.10. 1 hit.
HAMAPMF_01645. Hydantoinase.
InterProIPR017593. Allantoinase.
IPR011059. Metal-dep_hydrolase_composite.
[Graphical view]
SUPFAMSSF51338. SSF51338. 2 hits.
TIGRFAMsTIGR03178. allantoinase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameALLB_ENTFA
AccessionPrimary (citable) accession number: Q82ZQ1
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: June 1, 2003
Last modified: May 14, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways