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Q82Y02

- PUR5_NITEU

UniProt

Q82Y02 - PUR5_NITEU

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Protein

Phosphoribosylformylglycinamidine cyclo-ligase

Gene

purM

Organism
Nitrosomonas europaea (strain ATCC 19718 / NBRC 14298)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoribosylformylglycinamidine cyclo-ligase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. 'de novo' IMP biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Purine biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciNEUR228410:GJNO-98-MONOMER.
UniPathwayiUPA00074; UER00129.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoribosylformylglycinamidine cyclo-ligaseUniRule annotation (EC:6.3.3.1UniRule annotation)
Alternative name(s):
AIR synthaseUniRule annotation
AIRSUniRule annotation
Phosphoribosyl-aminoimidazole synthetaseUniRule annotation
Gene namesi
Name:purMUniRule annotation
Ordered Locus Names:NE0088
OrganismiNitrosomonas europaea (strain ATCC 19718 / NBRC 14298)
Taxonomic identifieri228410 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNitrosomonadalesNitrosomonadaceaeNitrosomonas
ProteomesiUP000001416: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 352352Phosphoribosylformylglycinamidine cyclo-ligasePRO_0000148226Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi228410.NE0088.

Structurei

3D structure databases

ProteinModelPortaliQ82Y02.
SMRiQ82Y02. Positions 13-346.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the AIR synthase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0150.
HOGENOMiHOG000229090.
KOiK01933.
OMAiGEATCEV.
OrthoDBiEOG61CM1V.
PhylomeDBiQ82Y02.

Family and domain databases

Gene3Di3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPiMF_00741. AIRS.
InterProiIPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view]
PfamiPF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view]
SUPFAMiSSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsiTIGR00878. purM. 1 hit.

Sequencei

Sequence statusi: Complete.

Q82Y02 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTASNPANPD KNPISYRSSG VDIDAGNRLV ERIKPFARRT MRPEALGGIG
60 70 80 90 100
GFGALFEVPG KYRQPVLVSG TDGVGTKLKL AFQYARHATI GIDLVAMSVN
110 120 130 140 150
DILVQGAEPL FFLDYFACGK LDVEIATQVV QGIAHGCEDA GCALIGGETA
160 170 180 190 200
EMPGMYPEGE YDLAGFAVGV VEKDRIIDGS GIRENDIVLG IASSGPHSNG
210 220 230 240 250
FSLIRKILDL NTVQSDTRLG ETSLIDALLT PTRIYVKSLL TLMAELPVKG
260 270 280 290 300
LAHITGGGLL ENIPRVLPDG VMAHIDSSTW VRPSLFDWLQ QHGNVAREEM
310 320 330 340 350
LRVFNCGIGM VVVIAPEHAQ TAIEILHNAG ETVWQIGEIR PRQSETLPIV

IA
Length:352
Mass (Da):37,790
Last modified:June 1, 2003 - v1
Checksum:i390E3A462F53DFEE
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL954747 Genomic DNA. Translation: CAD83999.1.
RefSeqiNP_840189.1. NC_004757.1.
WP_011110740.1. NC_004757.1.

Genome annotation databases

EnsemblBacteriaiCAD83999; CAD83999; NE0088.
GeneIDi1083609.
KEGGineu:NE0088.
PATRICi22710963. VBINitEur56163_0098.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL954747 Genomic DNA. Translation: CAD83999.1 .
RefSeqi NP_840189.1. NC_004757.1.
WP_011110740.1. NC_004757.1.

3D structure databases

ProteinModelPortali Q82Y02.
SMRi Q82Y02. Positions 13-346.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 228410.NE0088.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAD83999 ; CAD83999 ; NE0088 .
GeneIDi 1083609.
KEGGi neu:NE0088.
PATRICi 22710963. VBINitEur56163_0098.

Phylogenomic databases

eggNOGi COG0150.
HOGENOMi HOG000229090.
KOi K01933.
OMAi GEATCEV.
OrthoDBi EOG61CM1V.
PhylomeDBi Q82Y02.

Enzyme and pathway databases

UniPathwayi UPA00074 ; UER00129 .
BioCyci NEUR228410:GJNO-98-MONOMER.

Family and domain databases

Gene3Di 3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPi MF_00741. AIRS.
InterProi IPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view ]
Pfami PF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view ]
SUPFAMi SSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsi TIGR00878. purM. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of the ammonia-oxidizing bacterium and obligate chemolithoautotroph Nitrosomonas europaea."
    Chain P., Lamerdin J.E., Larimer F.W., Regala W., Lao V., Land M.L., Hauser L., Hooper A.B., Klotz M.G., Norton J., Sayavedra-Soto L.A., Arciero D.M., Hommes N.G., Whittaker M.M., Arp D.J.
    J. Bacteriol. 185:2759-2773(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 19718 / NBRC 14298.

Entry informationi

Entry nameiPUR5_NITEU
AccessioniPrimary (citable) accession number: Q82Y02
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 28, 2003
Last sequence update: June 1, 2003
Last modified: October 29, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3