Reviewed, UniProtKB/Swiss-Prot Q82XS4 (GPMA1_NITEU)

Names and origin

Protein names

Recommended name:
    2,3-bisphosphoglycerate-dependent phosphoglycerate mutase 1
      Short name=Phosphoglyceromutase 1
      Short name=PGAM 1
      Short name=BPG-dependent PGAM 1
      Short name=dPGM 1
    EC=5.4.2.1

Gene names

Name:	gpmA1
Ordered Locus Names:	NE0178

Organism

Nitrosomonas europaea [Complete proteome] [HAMAP]

Taxonomic identifier

915 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Nitrosomonadales › Nitrosomonadaceae › Nitrosomonas

Protein attributes

Sequence length	234 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate By similarity. HAMAP MF_01039
Catalytic activity	2-phospho-D-glycerate = 3-phospho-D-glycerate. HAMAP MF_01039
Pathway	Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5. HAMAP MF_01039
Sequence similarities	Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

Ontologies

Keywords
Biological process	Glycolysis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycolysis Inferred from electronic annotation. Source: HAMAP
Molecular function	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 234	234	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase 1 HAMAP MF_01039		PRO_0000179897
Sites
	Active site	15	1	Tele-phosphohistidine intermediate By similarity
	Active site	188	1	By similarity
	Site	66	1	Interaction with carboxyl group of phosphoglycerates By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q82XS4-1 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: 40D612055414EF38	FASTA	234	26,889
	10 20 30 40 50 60 MNEIQEPIRL VLLRHGQSIW NQDRHFTGWG DIVLSPQGEQ EALRAGHLLK QAGFTFDACF 70 80 90 100 110 120 CSELQRASDT LAIVQSVMGL NHLSTYRTWR LNERHYGALE GMRPWAAIRK FGIWSTMKSQ 130 140 150 160 170 180 IRFDAAPPLL MPDDPRAPVN QPRYAAVDRT QLPLAESMQQ TLERVRPLWQ ETILPEIRQG 190 200 210 220 230 KRLLIVSHQN LLKTLVMQLE GLTGAQIMRL SITTGHPLCY ELDHSLVPVK RYYL

References

[1]

"Complete genome sequence of the ammonia-oxidizing bacterium and obligate chemolithoautotroph Nitrosomonas europaea." Chain P., Lamerdin J.E., Larimer F.W., Regala W., Lao V., Land M.L., Hauser L., Hooper A.B., Klotz M.G., Norton J., Sayavedra-Soto L.A., Arciero D.M., Hommes N.G., Whittaker M.M., Arp D.J. J. Bacteriol. 185:2759-2773(2003) [PubMed: 12700255] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 19718 / IFO 14298.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL954747 Genomic DNA. Translation: CAD84089.1.
RefSeq	NP_840272.1.
3D structure databases
SMR	Q82XS4. Positions 9-234.
ModBase	Search...
Genome annotation databases
GeneID	1081105.
GenomeReviews	Gene locus NE0178 in contig AL954747_GR.
KEGG	neu:NE0178.
NMPDR	fig|228410.1.peg.171.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG658938.
OMA	ILPEIRQ.
Enzyme and pathway databases
BioCyc	NEUR228410:NE0178-MONOMER.
BRENDA	5.4.2.1. 444.
Family and domain databases
HAMAP	MF_01039. PGAM_GpmA. [Tree]
InterPro	IPR001345. PG/BPGM_mutase_AS. IPR013078. PG_mutase. IPR005952. Phosphogly_mut1. [Graphical view]
PANTHER	PTHR11931. Phosphogly_mut1. 1 hit.
Pfam	PF00300. PGAM. 1 hit. [Graphical view]
SMART	SM00855. PGAM. 1 hit. [Graphical view]
TIGRFAMs	TIGR01258. pgm_1. 1 hit.
PROSITE	PS00175. PG_MUTASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GPMA1_NITEU

Accession

Primary (citable) accession number: Q82XS4

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 19, 2004
Last sequence update:	June 1, 2003
Last modified:	February 9, 2010
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)