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Q82XC1 (SYR_NITEU) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 70. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:NE0364
OrganismNitrosomonas europaea (strain ATCC 19718 / NBRC 14298) [Complete proteome] [HAMAP]
Taxonomic identifier228410 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaNitrosomonadalesNitrosomonadaceaeNitrosomonas

Protein attributes

Sequence length586 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 586586Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_0000151584

Regions

Motif131 – 14111"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q82XC1 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: 9805D987D450E44D

FASTA58665,671
        10         20         30         40         50         60 
MVTTTLPDFK SHCIQLLDQA ARQVLPDEVG VQIELLRPKL ADHGDYSSNL AMKLARRLRR 

        70         80         90        100        110        120 
NPLELAKALI GALPDSSCVE KADVAGGGFI NFFLKKTAKQ QFLHAVLQAG DSFGHSRLGA 

       130        140        150        160        170        180 
GKTIQIEFVS ANPTGPLHVG HGRGAAFGAS LANIMTAAGY AVTREFYVND AGRQMDILTL 

       190        200        210        220        230        240 
STWLRYLDLC GLSFSFPANA YRGQYVADMA SEIYQAQGDR YAHRSDATIR QLTEISTSTT 

       250        260        270        280        290        300 
IDSEDERLDR LITAAKSILD QDYADLHNFV LTEQLADCRN DLMEFGVEFE TWFSEQSLFD 

       310        320        330        340        350        360 
SGMVARAVQL LDDKKLLYRQ DGALWFRSTD FGDEKDRVVQ RENGLYTYFA SDIAYHLSKY 

       370        380        390        400        410        420 
ERGFDYLLNI WGADHHGYIP RVKGAIEALS LDPGRLEIAL VQFAVLYRDG KKVSMSTRSG 

       430        440        450        460        470        480 
EFVTLRQLRQ EVGNDAARFF YVLRKSDQHL DFDLDLAKSQ SNDNPVYYVQ YAHARICSVL 

       490        500        510        520        530        540 
GQWGGAEDIL ARAETELLTD PAELVLLQKM IDFTDTIEAA AKERAPHLIA FFLRELAGEF 

       550        560        570        580 
HSYYNSTRFL VEDESLKITR LALISAVRQI LSKGLTLLGV TAPREM 

« Hide

References

[1]"Complete genome sequence of the ammonia-oxidizing bacterium and obligate chemolithoautotroph Nitrosomonas europaea."
Chain P., Lamerdin J.E., Larimer F.W., Regala W., Lao V., Land M.L., Hauser L., Hooper A.B., Klotz M.G., Norton J., Sayavedra-Soto L.A., Arciero D.M., Hommes N.G., Whittaker M.M., Arp D.J.
J. Bacteriol. 185:2759-2773(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 19718 / NBRC 14298.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL954747 Genomic DNA. Translation: CAD84275.1.
RefSeqNP_840451.1. NC_004757.1.

3D structure databases

ProteinModelPortalQ82XC1.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING228410.NE0364.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAD84275; CAD84275; NE0364.
GeneID1081295.
KEGGneu:NE0364.
PATRIC22711579. VBINitEur56163_0402.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247214.
KOK01887.
OMAPRVKGAI.
OrthoDBEOG6JB13C.
PhylomeDBQ82XC1.

Enzyme and pathway databases

BioCycNEUR228410:GJNO-376-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_NITEU
AccessionPrimary (citable) accession number: Q82XC1
Entry history
Integrated into UniProtKB/Swiss-Prot: December 15, 2003
Last sequence update: June 1, 2003
Last modified: July 9, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries