ID RL3_NITEU Reviewed; 215 AA. AC Q82X88; DT 16-FEB-2004, integrated into UniProtKB/Swiss-Prot. DT 01-JUN-2003, sequence version 1. DT 27-MAR-2024, entry version 101. DE RecName: Full=Large ribosomal subunit protein uL3 {ECO:0000255|HAMAP-Rule:MF_01325}; DE AltName: Full=50S ribosomal protein L3 {ECO:0000305}; GN Name=rplC {ECO:0000255|HAMAP-Rule:MF_01325}; OrderedLocusNames=NE0401; OS Nitrosomonas europaea (strain ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC OS 14298). OC Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales; OC Nitrosomonadaceae; Nitrosomonas. OX NCBI_TaxID=228410; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC 14298; RX PubMed=12700255; DOI=10.1128/jb.185.9.2759-2773.2003; RA Chain P., Lamerdin J.E., Larimer F.W., Regala W., Lao V., Land M.L., RA Hauser L., Hooper A.B., Klotz M.G., Norton J., Sayavedra-Soto L.A., RA Arciero D.M., Hommes N.G., Whittaker M.M., Arp D.J.; RT "Complete genome sequence of the ammonia-oxidizing bacterium and obligate RT chemolithoautotroph Nitrosomonas europaea."; RL J. Bacteriol. 185:2759-2773(2003). CC -!- FUNCTION: One of the primary rRNA binding proteins, it binds directly CC near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S CC subunit. {ECO:0000255|HAMAP-Rule:MF_01325}. CC -!- SUBUNIT: Part of the 50S ribosomal subunit. Forms a cluster with CC proteins L14 and L19. {ECO:0000255|HAMAP-Rule:MF_01325}. CC -!- PTM: Methylated by PrmB. {ECO:0000255|HAMAP-Rule:MF_01325}. CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL3 family. CC {ECO:0000255|HAMAP-Rule:MF_01325}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AL954747; CAD84312.1; -; Genomic_DNA. DR AlphaFoldDB; Q82X88; -. DR SMR; Q82X88; -. DR STRING; 228410.NE0401; -. DR KEGG; neu:NE0401; -. DR eggNOG; COG0087; Bacteria. DR HOGENOM; CLU_044142_4_1_4; -. DR OrthoDB; 9806135at2; -. DR PhylomeDB; Q82X88; -. DR Proteomes; UP000001416; Chromosome. DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProtKB-KW. DR GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW. DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule. DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro. DR GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule. DR Gene3D; 3.30.160.810; -; 1. DR Gene3D; 2.40.30.10; Translation factors; 1. DR HAMAP; MF_01325_B; Ribosomal_uL3_B; 1. DR InterPro; IPR000597; Ribosomal_uL3. DR InterPro; IPR019927; Ribosomal_uL3_bac/org-type. DR InterPro; IPR019926; Ribosomal_uL3_CS. DR InterPro; IPR009000; Transl_B-barrel_sf. DR NCBIfam; TIGR03625; L3_bact; 1. DR PANTHER; PTHR11229:SF8; 39S RIBOSOMAL PROTEIN L3, MITOCHONDRIAL; 1. DR PANTHER; PTHR11229; 50S RIBOSOMAL PROTEIN L3; 1. DR Pfam; PF00297; Ribosomal_L3; 1. DR SUPFAM; SSF50447; Translation proteins; 1. DR PROSITE; PS00474; RIBOSOMAL_L3; 1. PE 3: Inferred from homology; KW Methylation; Reference proteome; Ribonucleoprotein; Ribosomal protein; KW RNA-binding; rRNA-binding. FT CHAIN 1..215 FT /note="Large ribosomal subunit protein uL3" FT /id="PRO_0000077128" FT REGION 131..150 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 131..147 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT MOD_RES 153 FT /note="N5-methylglutamine" FT /evidence="ECO:0000255|HAMAP-Rule:MF_01325" SQ SEQUENCE 215 AA; 22847 MW; A18BEBEB22ACB44C CRC64; MKLGLIGKKI GMTRVFTESG NSIPVTVLDV SGNRVVQVKT EEKDGYSAVQ LTQGYRRKNR ITKALSGHFS QAGVEAGTVI KEFRVDHDIG SDIKIGSEIS VELFEVGSKV DVCGISIGKG YAGTIKRHNF SSSRASHGNS RSHNVPGSIG MAQDPGRVFP GKKMTGHLGN AQCTVQNIEV VRVDAGRGLL FLKGSVPGSK GNGVFIRPGV KQPSK //