Q82WX6 (GLMM_NITEU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoglucosamine mutase
EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	NE0530

Organism

Nitrosomonas europaea [Complete proteome] [HAMAP]

Taxonomic identifier

915 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Nitrosomonadales › Nitrosomonadaceae › Nitrosomonas

Protein attributes

Sequence length	458 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity. HAMAP MF_01554_B
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554_B
Cofactor	Binds 1 magnesium ion per subunit By similarity. HAMAP MF_01554_B
Post-translational modification	Activated by phosphorylation By similarity. HAMAP MF_01554_B
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: InterPro phosphoglucosamine mutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 458	458	Phosphoglucosamine mutase HAMAP MF_01554_B		PRO_0000147925
Sites
	Active site	108	1	Phosphoserine intermediate By similarity
	Metal binding	108	1	Magnesium; via phosphate group By similarity
	Metal binding	247	1	Magnesium By similarity
	Metal binding	249	1	Magnesium By similarity
	Metal binding	251	1	Magnesium By similarity
Amino acid modifications
	Modified residue	108	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q82WX6 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: 75CC7701E0930B7D	FASTA	458	49,702
	10 20 30 40 50 60 MKKKYFGTDG IRGKVGDFPI TPDFFLRLGY AVGKVLLASD RQLAADKRPT VLIGKDTRIS 70 80 90 100 110 120 GYMLESALEA GFSAAGVDVL LSGPLPTPAV AYLVRALRIQ AGAVISASHN PFDDNGIKFF 130 140 150 160 170 180 SSAGSKLPDS MELQIEAELD QPMKTTPSIK LGRVQRLRDA AGRYIEFCKS TFPNQLDLRG 190 200 210 220 230 240 LRIVVDCANG ADYHIAGHVM HELGADVITT HASPDGFNIN YECGATHIET LQGSILQHKA 250 260 270 280 290 300 DIGIAVDGDG DRVLMVSREG VLYDGDSLAY IIAKHRQQLG ELQGGVAGTL MTNLAVEQAF 310 320 330 340 350 360 ERLGIPFARA NVGDRYVSEL LQQNDWYLGA ENSGHIICRD KHTTGDGIIS ALQVLYALRD 370 380 390 400 410 420 TGLTLADFMR DVPFFPQRLI NVKVSGNFDF RSNPAVAACK NEAEQALGND GRILLRASGT 430 440 450 EPLIRVMVEG KVLQQTDYWA EKIAETIRQQ AASSMTGS

References

[1]

"Complete genome sequence of the ammonia-oxidizing bacterium and obligate chemolithoautotroph Nitrosomonas europaea." Chain P., Lamerdin J.E., Larimer F.W., Regala W., Lao V., Land M.L., Hauser L., Hooper A.B., Klotz M.G., Norton J., Sayavedra-Soto L.A., Arciero D.M., Hommes N.G., Whittaker M.M., Arp D.J. J. Bacteriol. 185:2759-2773(2003) [PubMed: 12700255] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 19718 / NBRC 14298.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL954747 Genomic DNA. Translation: CAD84441.1.
RefSeq	NP_840615.1. NC_004757.1.
3D structure databases
ProteinModelPortal	Q82WX6.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1081469.
GenomeReviews	Gene locus NE0530 in contig AL954747_GR.
KEGG	neu:NE0530.
NMPDR	fig|228410.1.peg.514.
PATRIC	22711976. VBINitEur56163_0593.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG644964.
OMA	PLEDIQV.
ProtClustDB	PRK10887.
Enzyme and pathway databases
BioCyc	NEUR228410:NE0530-MONOMER.
Family and domain databases
HAMAP	MF_01554_B. GlmM_B. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR005841. Alpha-D-phosphohexomutase_SF. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
KO	K03431.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
SUPFAM	SSF53738. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
TIGRFAMs	TIGR01455. GlmM. 1 hit.
PROSITE	PS00710. PGM_PMM. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_NITEU

Accession

Primary (citable) accession number: Q82WX6

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 20, 2005
Last sequence update:	June 1, 2003
Last modified:	January 25, 2012
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program