SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q82W22

- Q82W22_NITEU

UniProt

Q82W22 - Q82W22_NITEU

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Bifunctional purine biosynthesis protein PurH
Gene
purH, NE0876
Organism
Nitrosomonas europaea (strain ATCC 19718 / NBRC 14298)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

10-formyltetrahydrofolate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide = tetrahydrofolate + 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide.UniRule annotationSAAS annotations
IMP + H2O = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide.UniRule annotationSAAS annotations

Pathwayi

GO - Molecular functioni

  1. IMP cyclohydrolase activity Source: UniProtKB-HAMAP
  2. phosphoribosylaminoimidazolecarboxamide formyltransferase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. 'de novo' IMP biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

HydrolaseUniRule annotationSAAS annotations, TransferaseUniRule annotationSAAS annotationsImported

Keywords - Biological processi

Purine biosynthesisUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciNEUR228410:GJNO-898-MONOMER.
UniPathwayiUPA00074; UER00133.
UPA00074; UER00135.

Names & Taxonomyi

Protein namesi
Recommended name:
Bifunctional purine biosynthesis protein PurHUniRule annotation
Gene namesi
Name:purHUniRule annotationImported
Ordered Locus Names:NE0876Imported
OrganismiNitrosomonas europaea (strain ATCC 19718 / NBRC 14298)Imported
Taxonomic identifieri228410 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNitrosomonadalesNitrosomonadaceaeNitrosomonas
ProteomesiUP000001416: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi228410.NE0876.

Structurei

3D structure databases

ProteinModelPortaliQ82W22.

Family & Domainsi

Domaini

The IMP cyclohydrolase activity resides in the N-terminal region By similarity.UniRule annotation

Sequence similaritiesi

Belongs to the PurH family.UniRule annotation

Keywords - Domaini

TransmembraneImported

Phylogenomic databases

HOGENOMiHOG000230373.
KOiK00602.
OMAiCGVATGP.
OrthoDBiEOG6QCDFF.
PhylomeDBiQ82W22.

Family and domain databases

Gene3Di3.40.140.20. 2 hits.
3.40.50.1380. 1 hit.
HAMAPiMF_00139. PurH.
InterProiIPR024051. AICAR_Tfase_dom.
IPR002695. AICARFT_IMPCHas.
IPR016193. Cytidine_deaminase-like.
IPR011607. MGS-like_dom.
[Graphical view]
PANTHERiPTHR11692. PTHR11692. 1 hit.
PfamiPF01808. AICARFT_IMPCHas. 1 hit.
PF02142. MGS. 1 hit.
[Graphical view]
PIRSFiPIRSF000414. AICARFT_IMPCHas. 1 hit.
SMARTiSM00798. AICARFT_IMPCHas. 1 hit.
SM00851. MGS. 1 hit.
[Graphical view]
SUPFAMiSSF52335. SSF52335. 1 hit.
SSF53927. SSF53927. 1 hit.
TIGRFAMsiTIGR00355. purH. 1 hit.

Sequencei

Sequence statusi: Complete.

Q82W22-1 [UniParc]FASTAAdd to Basket

« Hide

MSIKQALISV SDKTGIVELA AALHQFNITI LSTGGTARLL QESGIPVIEV    50
SDYTGFPEML DGRVKTLHPK VHAGILARMD LPEHRQVMEQ AQIPAIDLVV 100
VNLYPFTQTI TRPDCSFEEA IENIDIGGPT MIRAAAKNFQ RVAVVTDPQD 150
YGPLLEQIRA NDGSIDHDYR FQLAQKAFSH TARYDGAISN YLTALEPLSS 200
QRKRFPDQLN LSFTLAQPLR YGENPHQQAA FYRDTTNVPG SLADYDQLQG 250
KELSYNNIAD TDAAWACVRT FDKPACVIIK HANPCGVAIA DTALAAYKKA 300
FTTDPVSAFG GIIAINRAVE ADLAKAVLQQ FVEVIIAPEF SPEARHLLAD 350
KPNIRVLTVP LDKHNNVYDL KRVDGGLLVQ TPDDLDITVD QLQVVTRIKP 400
TREQIEDCLF AWRVAKFVKS NTIVFCANGQ TLGIGAGQMS RVDSARIASI 450
KAQQANLDLH GSVVASDAFF PFRDGLDVLA QAGAGVVIQP GGSIRDEEVI 500
AAADEQGVAM VFTGVRHFRH 520
Length:520
Mass (Da):56,796
Last modified:June 1, 2003 - v1
Checksum:i6376875F7A0E9394
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL954747 Genomic DNA. Translation: CAD84787.1.
RefSeqiNP_840950.1. NC_004757.1.

Genome annotation databases

EnsemblBacteriaiCAD84787; CAD84787; NE0876.
GeneIDi1081817.
KEGGineu:NE0876.
PATRICi22712762. VBINitEur56163_0983.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL954747 Genomic DNA. Translation: CAD84787.1 .
RefSeqi NP_840950.1. NC_004757.1.

3D structure databases

ProteinModelPortali Q82W22.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 228410.NE0876.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAD84787 ; CAD84787 ; NE0876 .
GeneIDi 1081817.
KEGGi neu:NE0876.
PATRICi 22712762. VBINitEur56163_0983.

Phylogenomic databases

HOGENOMi HOG000230373.
KOi K00602.
OMAi CGVATGP.
OrthoDBi EOG6QCDFF.
PhylomeDBi Q82W22.

Enzyme and pathway databases

UniPathwayi UPA00074 ; UER00133 .
UPA00074 ; UER00135 .
BioCyci NEUR228410:GJNO-898-MONOMER.

Family and domain databases

Gene3Di 3.40.140.20. 2 hits.
3.40.50.1380. 1 hit.
HAMAPi MF_00139. PurH.
InterProi IPR024051. AICAR_Tfase_dom.
IPR002695. AICARFT_IMPCHas.
IPR016193. Cytidine_deaminase-like.
IPR011607. MGS-like_dom.
[Graphical view ]
PANTHERi PTHR11692. PTHR11692. 1 hit.
Pfami PF01808. AICARFT_IMPCHas. 1 hit.
PF02142. MGS. 1 hit.
[Graphical view ]
PIRSFi PIRSF000414. AICARFT_IMPCHas. 1 hit.
SMARTi SM00798. AICARFT_IMPCHas. 1 hit.
SM00851. MGS. 1 hit.
[Graphical view ]
SUPFAMi SSF52335. SSF52335. 1 hit.
SSF53927. SSF53927. 1 hit.
TIGRFAMsi TIGR00355. purH. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of the ammonia-oxidizing bacterium and obligate chemolithoautotroph Nitrosomonas europaea."
    Chain P., Lamerdin J.E., Larimer F.W., Regala W., Lao V., Land M.L., Hauser L., Hooper A.B., Klotz M.G., Norton J., Sayavedra-Soto L.A., Arciero D.M., Hommes N.G., Whittaker M.M., Arp D.J.
    J. Bacteriol. 185:2759-2773(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 19718 / NBRC 14298.

Entry informationi

Entry nameiQ82W22_NITEU
AccessioniPrimary (citable) accession number: Q82W22
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: June 11, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Multifunctional enzymeUniRule annotationSAAS annotations

External Data

Dasty 3

Similar proteinsi