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Q82SP4 (G6PI_NITEU) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:NE2263
OrganismNitrosomonas europaea (strain ATCC 19718 / NBRC 14298) [Complete proteome] [HAMAP]
Taxonomic identifier228410 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaNitrosomonadalesNitrosomonadaceaeNitrosomonas

Protein attributes

Sequence length544 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 544544Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_0000180695

Sites

Active site3511Proton donor By similarity
Active site3821 By similarity
Active site5101 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q82SP4 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: A4BEF605C8A38CF3

FASTA54460,902
        10         20         30         40         50         60 
MSTLTRSPAW LALSAHQTEI ANRPLRTLFD EDPQRFDKFS LQFKDLLLDY SKQPVDATTI 

        70         80         90        100        110        120 
RLLLALAEQQ KLVDWLGRMA NGEKINFTES RAALHIALRA NSPVFMDGVD VTQEVRRVLR 

       130        140        150        160        170        180 
QIEQFVQKIH NQSHRGYSGL PITDVVNIGI GGSDLGPVMV TEALKPYHLP QLRTHFVSNL 

       190        200        210        220        230        240 
DGAHLSDTLQ HINPATTLFV IASKTFTTQE TLANAHSARK WFLAGGGSKQ DIAAHFVAVS 

       250        260        270        280        290        300 
TNREAVSQFG IDPDNMFEFW DWVGGRYSLW SAIGLPIALA VGMEHFHSLL AGAQAMDDHF 

       310        320        330        340        350        360 
LTAPFEQNLP VILGLIGIWQ INFFHITSQA ILPYDQSMHR FPAYLQQLEM ESNGKRVTRN 

       370        380        390        400        410        420 
GEAVDYSTGI IIWGEPGTNG QHAFYQLLHQ GTQKFTADFL APCRCHHPLS EHHPMLLANF 

       430        440        450        460        470        480 
FAQTEALMRG KTEQEVRSEL ANQNLSADLV EHLLPHRVFP GNHATTSILF KKLDPATLGM 

       490        500        510        520        530        540 
LIALYEHKVF VQSVIWEINP FDQWGVELGK QLAGKILAEL ALDKPVTGHD ASTNGLINFY 


RAQQ 

« Hide

References

[1]"Complete genome sequence of the ammonia-oxidizing bacterium and obligate chemolithoautotroph Nitrosomonas europaea."
Chain P., Lamerdin J.E., Larimer F.W., Regala W., Lao V., Land M.L., Hauser L., Hooper A.B., Klotz M.G., Norton J., Sayavedra-Soto L.A., Arciero D.M., Hommes N.G., Whittaker M.M., Arp D.J.
J. Bacteriol. 185:2759-2773(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 19718 / NBRC 14298.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL954747 Genomic DNA. Translation: CAD86175.1.
RefSeqNP_842265.1. NC_004757.1.

3D structure databases

ProteinModelPortalQ82SP4.
SMRQ82SP4. Positions 2-544.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING228410.NE2263.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAD86175; CAD86175; NE2263.
GeneID1083230.
KEGGneu:NE2263.
PATRIC22715925. VBINitEur56163_2540.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000261370.
KOK01810.
OMALKMHFVS.
OrthoDBEOG64R61J.
ProtClustDBPRK00179.

Enzyme and pathway databases

BioCycNEUR228410:GJNO-2308-MONOMER.
UniPathwayUPA00109; UER00181.

Family and domain databases

Gene3D1.10.1390.10. 1 hit.
HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_NITEU
AccessionPrimary (citable) accession number: Q82SP4
Entry history
Integrated into UniProtKB/Swiss-Prot: March 29, 2005
Last sequence update: June 1, 2003
Last modified: February 19, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways