ID   Q82QR8_STRAW            Unreviewed;       808 AA.
AC   Q82QR8;
DT   01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2003, sequence version 1.
DT   27-MAR-2024, entry version 110.
DE   SubName: Full=Magnesium or manganese-dependent protein phosphatase {ECO:0000313|EMBL:BAC68147.1};
GN   Name=prpM1 {ECO:0000313|EMBL:BAC68147.1};
GN   ORFNames=SAVERM_437 {ECO:0000313|EMBL:BAC68147.1};
OS   Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC
OS   14893 / NCIMB 12804 / NRRL 8165 / MA-4680).
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=227882 {ECO:0000313|EMBL:BAC68147.1, ECO:0000313|Proteomes:UP000000428};
RN   [1] {ECO:0000313|EMBL:BAC68147.1, ECO:0000313|Proteomes:UP000000428}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 /
RC   NRRL 8165 / MA-4680 {ECO:0000313|Proteomes:UP000000428};
RX   PubMed=11572948; DOI=10.1073/pnas.211433198;
RA   Omura S., Ikeda H., Ishikawa J., Hanamoto A., Takahashi C., Shinose M.,
RA   Takahashi Y., Horikawa H., Nakazawa H., Osonoe T., Kikuchi H., Shiba T.,
RA   Sakaki Y., Hattori M.;
RT   "Genome sequence of an industrial microorganism Streptomyces avermitilis:
RT   deducing the ability of producing secondary metabolites.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:12215-12220(2001).
RN   [2] {ECO:0000313|EMBL:BAC68147.1, ECO:0000313|Proteomes:UP000000428}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 /
RC   NRRL 8165 / MA-4680 {ECO:0000313|Proteomes:UP000000428};
RX   PubMed=12692562; DOI=10.1038/nbt820;
RA   Ikeda H., Ishikawa J., Hanamoto A., Shinose M., Kikuchi H., Shiba T.,
RA   Sakaki Y., Hattori M., Omura S.;
RT   "Complete genome sequence and comparative analysis of the industrial
RT   microorganism Streptomyces avermitilis.";
RL   Nat. Biotechnol. 21:526-531(2003).
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DR   EMBL; BA000030; BAC68147.1; -; Genomic_DNA.
DR   RefSeq; WP_010981875.1; NZ_JZJK01000088.1.
DR   AlphaFoldDB; Q82QR8; -.
DR   KEGG; sma:SAVERM_437; -.
DR   eggNOG; COG2203; Bacteria.
DR   eggNOG; COG2208; Bacteria.
DR   HOGENOM; CLU_000445_43_3_11; -.
DR   OrthoDB; 3894297at2; -.
DR   Proteomes; UP000000428; Chromosome.
DR   CDD; cd16936; HATPase_RsbW-like; 1.
DR   CDD; cd00130; PAS; 1.
DR   Gene3D; 3.30.450.40; -; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 2.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   InterPro; IPR003018; GAF.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013656; PAS_4.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   PANTHER; PTHR43156:SF2; MULTIDOMAIN REGULATORY PROTEIN RV1364C; 1.
DR   PANTHER; PTHR43156; STAGE II SPORULATION PROTEIN E-RELATED; 1.
DR   Pfam; PF13185; GAF_2; 1.
DR   Pfam; PF13581; HATPase_c_2; 1.
DR   Pfam; PF08448; PAS_4; 1.
DR   Pfam; PF07228; SpoIIE; 1.
DR   SMART; SM00065; GAF; 1.
DR   SMART; SM00331; PP2C_SIG; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   SUPFAM; SSF55781; GAF domain-like; 1.
DR   SUPFAM; SSF81606; PP2C-like; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR   PROSITE; PS50112; PAS; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000000428}.
FT   DOMAIN          21..76
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
SQ   SEQUENCE   808 AA;  88059 MW;  3D2ADFE3402B2D85 CRC64;
     MHDITFRGDG EFPEPGSEAD VLLDACGRVA AWGPGAQQML GCPAREAVGR SADEFLYDPA
     DAADIVRRWE KGARRGSLVL RQRSGKPLAA QIWVRALTSA NGDPQWLVQA ARTAVLRTYE
     YGRALLKGLF TDSPFNIDIF DTQLRFVGLN IAERRAGVFQ GTEYSGHTMR EMAPPGLLDV
     DALEARQRRV LETGKALIDT EVVGHPVANS PREYVWSESI LPLRDPSGRV IALGHVVSDV
     TQRVRSRERL VLTNEAAIGI GTTLDLWRTA RELAEVAVPR FADICFVDLL DSVFPGREPT
     EGRPPRPPLF RRAACSGAAE DTGSDAAGEV KVGDANLWAT APGSPFLDAL TKGESVLLAD
     DQLQNCPAAV GLRHSPDDGP KIHSWLLVPM FARGVVLGAV VFLRSGNPRR FEPDDVLLAE
     EIVTRAAVCV DNASRYHRER TTALTLQRSL LPQRLPSASA VRTASCYLPA SGHTGLGGDW
     FDVIPLSGAR VALVVGDVTG HDLQSAVTMG RLRSAVRTLA DLDLAPDELL THLDDQMNRF
     LDERSDEGPL ATGATCLYAV YDPVSRRCLL ARAGHPPPAV LSVNGAVDFV ELPGGPPLGL
     GGIVFEKREI AMDDGDVLVL YTNGLLQPRA QDLDAGLHRM RDTLSRTPPS ATPQEVCDTL
     VRELLPTCHK DDVAVLTARV SGLASDRHVT WKIEAQDELV GRARDLTTQQ MARWGLEEES
     FTTELIVSEL VTNAIRYGEE PITLRLILDR NVICEVSDGS STSPHVRRAQ DTDEGGRGLY
     LITQLTRSWG TRYGERGKTI WAEQPLRC
//