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Q82QK2

- IF12_STRAW

UniProt

Q82QK2 - IF12_STRAW

Protein

Translation initiation factor IF-1 2

Gene

infA2

Organism
Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NCIMB 12804 / NRRL 8165 / MA-4680)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
  1. Functioni

    No specific function has so far been attributed to this initiation factor; however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3.UniRule annotation

    GO - Molecular functioni

    1. translation initiation factor activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Initiation factor

    Keywords - Biological processi

    Protein biosynthesis

    Enzyme and pathway databases

    BioCyciSAVE227882:GJU1-509-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Translation initiation factor IF-1 2UniRule annotation
    Gene namesi
    Name:infA2UniRule annotation
    Ordered Locus Names:SAV_504
    OrganismiStreptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NCIMB 12804 / NRRL 8165 / MA-4680)
    Taxonomic identifieri227882 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces
    ProteomesiUP000000428: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 7474Translation initiation factor IF-1 2PRO_0000095876Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi227882.SAV_504.

    Structurei

    3D structure databases

    ProteinModelPortaliQ82QK2.
    SMRiQ82QK2. Positions 8-73.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini1 – 7373S1-likeUniRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the IF-1 family.UniRule annotation
    Contains 1 S1-like domain.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0361.
    HOGENOMiHOG000221323.
    KOiK02518.
    OMAiCHISGKI.
    OrthoDBiEOG6384SC.

    Family and domain databases

    Gene3Di2.40.50.140. 1 hit.
    HAMAPiMF_00075. IF_1.
    InterProiIPR012340. NA-bd_OB-fold.
    IPR022967. RNA-binding_domain_S1.
    IPR006196. RNA-binding_domain_S1_IF1.
    IPR004368. TIF_IF1.
    [Graphical view]
    PfamiPF01176. eIF-1a. 1 hit.
    [Graphical view]
    SMARTiSM00316. S1. 1 hit.
    [Graphical view]
    SUPFAMiSSF50249. SSF50249. 1 hit.
    TIGRFAMsiTIGR00008. infA. 1 hit.
    PROSITEiPS50832. S1_IF1_TYPE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q82QK2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTKNKNVIEV EGKVVECLRS AMFTVELENG HQVLAHISGK IRKNYIKIML   50
    EDRVLVELPP YDLTRGRIVF RYRN 74
    Length:74
    Mass (Da):8,673
    Last modified:June 1, 2003 - v1
    Checksum:i10C3F181B6A21D5D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000030 Genomic DNA. Translation: BAC68214.1.
    RefSeqiNP_821679.1. NC_003155.4.

    Genome annotation databases

    EnsemblBacteriaiBAC68214; BAC68214; SAV_504.
    GeneIDi1210047.
    KEGGisma:SAV_504.
    PATRICi23714272. VBIStrAve112782_0554.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000030 Genomic DNA. Translation: BAC68214.1 .
    RefSeqi NP_821679.1. NC_003155.4.

    3D structure databases

    ProteinModelPortali Q82QK2.
    SMRi Q82QK2. Positions 8-73.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 227882.SAV_504.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAC68214 ; BAC68214 ; SAV_504 .
    GeneIDi 1210047.
    KEGGi sma:SAV_504.
    PATRICi 23714272. VBIStrAve112782_0554.

    Phylogenomic databases

    eggNOGi COG0361.
    HOGENOMi HOG000221323.
    KOi K02518.
    OMAi CHISGKI.
    OrthoDBi EOG6384SC.

    Enzyme and pathway databases

    BioCyci SAVE227882:GJU1-509-MONOMER.

    Family and domain databases

    Gene3Di 2.40.50.140. 1 hit.
    HAMAPi MF_00075. IF_1.
    InterProi IPR012340. NA-bd_OB-fold.
    IPR022967. RNA-binding_domain_S1.
    IPR006196. RNA-binding_domain_S1_IF1.
    IPR004368. TIF_IF1.
    [Graphical view ]
    Pfami PF01176. eIF-1a. 1 hit.
    [Graphical view ]
    SMARTi SM00316. S1. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50249. SSF50249. 1 hit.
    TIGRFAMsi TIGR00008. infA. 1 hit.
    PROSITEi PS50832. S1_IF1_TYPE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites."
      Omura S., Ikeda H., Ishikawa J., Hanamoto A., Takahashi C., Shinose M., Takahashi Y., Horikawa H., Nakazawa H., Osonoe T., Kikuchi H., Shiba T., Sakaki Y., Hattori M.
      Proc. Natl. Acad. Sci. U.S.A. 98:12215-12220(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 31267 / DSM 46492 / JCM 5070 / NCIMB 12804 / NRRL 8165 / MA-4680.
    2. "Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis."
      Ikeda H., Ishikawa J., Hanamoto A., Shinose M., Kikuchi H., Shiba T., Sakaki Y., Hattori M., Omura S.
      Nat. Biotechnol. 21:526-531(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 31267 / DSM 46492 / JCM 5070 / NCIMB 12804 / NRRL 8165 / MA-4680.

    Entry informationi

    Entry nameiIF12_STRAW
    AccessioniPrimary (citable) accession number: Q82QK2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 1, 2004
    Last sequence update: June 1, 2003
    Last modified: October 1, 2014
    This is version 72 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Translation initiation factors
      List of translation initiation factor entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3