ID   Q82QC4_STRAW            Unreviewed;       820 AA.
AC   Q82QC4;
DT   01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2003, sequence version 1.
DT   27-MAR-2024, entry version 120.
DE   SubName: Full=Magnesium or manganese-dependent protein phosphatase {ECO:0000313|EMBL:BAC68296.1};
GN   Name=prpL1 {ECO:0000313|EMBL:BAC68296.1};
GN   ORFNames=SAVERM_586 {ECO:0000313|EMBL:BAC68296.1};
OS   Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC
OS   14893 / NCIMB 12804 / NRRL 8165 / MA-4680).
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=227882 {ECO:0000313|EMBL:BAC68296.1, ECO:0000313|Proteomes:UP000000428};
RN   [1] {ECO:0000313|EMBL:BAC68296.1, ECO:0000313|Proteomes:UP000000428}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 /
RC   NRRL 8165 / MA-4680 {ECO:0000313|Proteomes:UP000000428};
RX   PubMed=11572948; DOI=10.1073/pnas.211433198;
RA   Omura S., Ikeda H., Ishikawa J., Hanamoto A., Takahashi C., Shinose M.,
RA   Takahashi Y., Horikawa H., Nakazawa H., Osonoe T., Kikuchi H., Shiba T.,
RA   Sakaki Y., Hattori M.;
RT   "Genome sequence of an industrial microorganism Streptomyces avermitilis:
RT   deducing the ability of producing secondary metabolites.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:12215-12220(2001).
RN   [2] {ECO:0000313|EMBL:BAC68296.1, ECO:0000313|Proteomes:UP000000428}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 /
RC   NRRL 8165 / MA-4680 {ECO:0000313|Proteomes:UP000000428};
RX   PubMed=12692562; DOI=10.1038/nbt820;
RA   Ikeda H., Ishikawa J., Hanamoto A., Shinose M., Kikuchi H., Shiba T.,
RA   Sakaki Y., Hattori M., Omura S.;
RT   "Complete genome sequence and comparative analysis of the industrial
RT   microorganism Streptomyces avermitilis.";
RL   Nat. Biotechnol. 21:526-531(2003).
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DR   EMBL; BA000030; BAC68296.1; -; Genomic_DNA.
DR   RefSeq; WP_010982024.1; NZ_JZJK01000088.1.
DR   AlphaFoldDB; Q82QC4; -.
DR   DNASU; 1212296; -.
DR   KEGG; sma:SAVERM_586; -.
DR   eggNOG; COG2203; Bacteria.
DR   eggNOG; COG2208; Bacteria.
DR   HOGENOM; CLU_000445_43_3_11; -.
DR   OrthoDB; 118142at2; -.
DR   Proteomes; UP000000428; Chromosome.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd16936; HATPase_RsbW-like; 1.
DR   CDD; cd00130; PAS; 1.
DR   Gene3D; 3.30.450.40; -; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 2.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   InterPro; IPR003018; GAF.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013656; PAS_4.
DR   InterPro; IPR013767; PAS_fold.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   NCBIfam; TIGR00229; sensory_box; 1.
DR   PANTHER; PTHR43156:SF2; MULTIDOMAIN REGULATORY PROTEIN RV1364C; 1.
DR   PANTHER; PTHR43156; STAGE II SPORULATION PROTEIN E-RELATED; 1.
DR   Pfam; PF01590; GAF; 1.
DR   Pfam; PF13581; HATPase_c_2; 1.
DR   Pfam; PF00989; PAS; 1.
DR   Pfam; PF08448; PAS_4; 1.
DR   Pfam; PF07228; SpoIIE; 1.
DR   SMART; SM00065; GAF; 1.
DR   SMART; SM00091; PAS; 2.
DR   SMART; SM00331; PP2C_SIG; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   SUPFAM; SSF55781; GAF domain-like; 1.
DR   SUPFAM; SSF81606; PP2C-like; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR   PROSITE; PS50112; PAS; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000000428}.
FT   DOMAIN          17..54
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   REGION          763..783
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   820 AA;  88372 MW;  78A6A9D92715A99B CRC64;
     MTKTDHTPLA EPVSPRETPD AAIAMLDAEG TVVGWTHAAE QLVGYSAGEV VGRSATHVLP
     PAEDVPSASV FAEQGRALDG WSGAVTVRHR DGHAIKMTLR ISLLWGQDAG TRWLVSVTDI
     GTLSSGTSDE AVRESLLAHA PVGIAVYDPR LRCTWVNDVM ERHDGTPRER RFGRRLRDSL
     PAVEAEALEV VMRQVLESGT TMVHEYRAWS STDQRREHAF SASFFCLQDA DGTALAVCSM
     SVDVTGNRRA RERLAILSEA STRIGSTLEV MRTGQELADL AVPLLADHAI VDLMESVPFG
     VDPSAGTGTA ANDRPPVLRR AGVASVDPGI LKLLMRQEVI RPFPTSLFAT VLRTGRSYLE
     SVLDTYSGPW ILHDPARTQM VRDSGVHSLM VVPIRARRCA LGLAVFCRSE EPTPFQEDDL
     LLAEELVTRA ALSLDNALQY ARQRTAALTL QRDLLPHHVG GGAALDVASR YVPADIDHGV
     GGDWFDVIKL SGARVALVVG DVVGHGINAA VTMGRLRTAV RTLANMELPP HELLAHLDDT
     VKRLSEEDAD APDQLPPAVG ATCLYAVYDP VTRRCTMSRA GHPPPAIIDP QGRATFPDMP
     AGAPLGLGLG LVPFESVELE LPEGTLLALY TDGLVESRDD DIDVGLDRLG AALAESGSAL
     EDLCSQVIET LPTQAPADDV TLLLARTRGL EPAQVASWEL PNEPAAVRIA RQAAARQLSE
     WGLDHLVTTE QLIVSELVTN AIRYSGGPIR LRLIQHQVLT CEVSDSNPSH PRPRQPHTID
     ENGRGLSLVA QLSHRWGSRS ATDGKIVWAE QDLPSKALAA
//