ID   Q82PH8_STRAW            Unreviewed;       828 AA.
AC   Q82PH8;
DT   01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2003, sequence version 1.
DT   27-MAR-2024, entry version 114.
DE   SubName: Full=Magnesium or manganese-dependent protein phosphatase {ECO:0000313|EMBL:BAC68634.1};
GN   Name=prpC4 {ECO:0000313|EMBL:BAC68634.1};
GN   ORFNames=SAVERM_924 {ECO:0000313|EMBL:BAC68634.1};
OS   Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC
OS   14893 / NCIMB 12804 / NRRL 8165 / MA-4680).
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=227882 {ECO:0000313|EMBL:BAC68634.1, ECO:0000313|Proteomes:UP000000428};
RN   [1] {ECO:0000313|EMBL:BAC68634.1, ECO:0000313|Proteomes:UP000000428}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 /
RC   NRRL 8165 / MA-4680 {ECO:0000313|Proteomes:UP000000428};
RX   PubMed=11572948; DOI=10.1073/pnas.211433198;
RA   Omura S., Ikeda H., Ishikawa J., Hanamoto A., Takahashi C., Shinose M.,
RA   Takahashi Y., Horikawa H., Nakazawa H., Osonoe T., Kikuchi H., Shiba T.,
RA   Sakaki Y., Hattori M.;
RT   "Genome sequence of an industrial microorganism Streptomyces avermitilis:
RT   deducing the ability of producing secondary metabolites.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:12215-12220(2001).
RN   [2] {ECO:0000313|EMBL:BAC68634.1, ECO:0000313|Proteomes:UP000000428}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 /
RC   NRRL 8165 / MA-4680 {ECO:0000313|Proteomes:UP000000428};
RX   PubMed=12692562; DOI=10.1038/nbt820;
RA   Ikeda H., Ishikawa J., Hanamoto A., Shinose M., Kikuchi H., Shiba T.,
RA   Sakaki Y., Hattori M., Omura S.;
RT   "Complete genome sequence and comparative analysis of the industrial
RT   microorganism Streptomyces avermitilis.";
RL   Nat. Biotechnol. 21:526-531(2003).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BA000030; BAC68634.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q82PH8; -.
DR   KEGG; sma:SAVERM_924; -.
DR   eggNOG; COG2203; Bacteria.
DR   eggNOG; COG2208; Bacteria.
DR   HOGENOM; CLU_000445_43_3_11; -.
DR   Proteomes; UP000000428; Chromosome.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd16936; HATPase_RsbW-like; 1.
DR   CDD; cd00130; PAS; 1.
DR   Gene3D; 3.30.450.40; -; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 2.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   InterPro; IPR003018; GAF.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013656; PAS_4.
DR   InterPro; IPR013767; PAS_fold.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   NCBIfam; TIGR00229; sensory_box; 1.
DR   PANTHER; PTHR43156:SF2; MULTIDOMAIN REGULATORY PROTEIN RV1364C; 1.
DR   PANTHER; PTHR43156; STAGE II SPORULATION PROTEIN E-RELATED; 1.
DR   Pfam; PF01590; GAF; 1.
DR   Pfam; PF13581; HATPase_c_2; 1.
DR   Pfam; PF00989; PAS; 1.
DR   Pfam; PF08448; PAS_4; 1.
DR   Pfam; PF07228; SpoIIE; 1.
DR   SMART; SM00065; GAF; 1.
DR   SMART; SM00091; PAS; 2.
DR   SMART; SM00331; PP2C_SIG; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   SUPFAM; SSF55781; GAF domain-like; 1.
DR   SUPFAM; SSF81606; PP2C-like; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR   PROSITE; PS50112; PAS; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000000428}.
FT   DOMAIN          26..71
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
SQ   SEQUENCE   828 AA;  90220 MW;  6C245A2825944C99 CRC64;
     MRRRETVVLW NRPPEGIHTM ATQSTAHEYL DEPFDITHAA VVRIDAHGLI EGWSKGAQTL
     LGYRASEILG RPAASLLTGE ADLASAMSEP RRTGNGWEGL IAVRHRSGHH VELALRACPF
     QDDGGRRSWL AVVTPVSAPR RWALEQAVLH GLLDQSPIGI AVVDTDLRYQ MVNRVLEDMD
     GVPVQLRIGR RVGEAVPGEA DSTLEWQARQ ALGSGQTLLM FQHAVPEPGE PYRQDRERVR
     LCASFRLQDR TGHLLGVCHT TVDVTDHDRA RQRLALVNEA SSRIGTTLDL DRTVRELAEI
     VVPQVADFVA VDLLDTVLAA RDLTPVAVDG ETALRRAAHL SIQEDHPEVV VAAGEPTRYP
     PTSPQSRCLA TGRSIRHPVI DGSTPWLAQD PLRKAKLDLL GVHSHLVVPL QARGMTMGVA
     TLLRWKHAEP FDDDDQLLVE ELAARAAVCI ENARRFAREH NTALALQHSL LPHGLPEQSA
     VEAAYRYLPT DTEAGVGGDW FDVIPLSGAR VALVVGDVVG HGIHAAATMG RLRTAVQTLA
     DLDLPPDELL ARLDDLVIRL ADEADAAAGG ALVIGGTCVY GIYDPISRKL VVARAGHPSP
     AIAHLREPVE FPDIPAGPPL GLGGLPFESA EIDVEEGSVI AFYTDGLIEA SDRDVDVGFE
     RLCFALAHPD RPLDEICDTM VRMLLPEHPH DDVAFLVART RALGADNVAS WDIPAVPSAV
     HTIRQMTNRQ LSAWDLDDAA FTTELIVSEL VTNAIRHASP PLSLRLIRER ALICEVSDSS
     NTSPHLRRPL GTDEGGRGLF LVAQVAQRWG TRYTPQGKTI WAEQPLPS
//