Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q82NX6 (Q82NX6_STRAW) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Adenosine deaminase 1 HAMAP MF_00540
EC=3.5.4.4 HAMAP MF_00540
Alternative name(s):
Adenosine aminohydrolase 1 HAMAP MF_00540
Gene names
Name:add1 HAMAP MF_00540 EMBL BAC68875.1
Ordered Locus Names:SAV_1165 EMBL BAC68875.1
OrganismStreptomyces avermitilis [Complete proteome] [HAMAP]
Taxonomic identifier33903 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Streptomycineae › Streptomycetaceae › Streptomyces

Protein attributes

Sequence length354 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Adenosine + H2O = inosine + NH3. HAMAP MF_00540

Cofactor

Binds 1 zinc ion per subunit By similarity. HAMAP MF_00540 SAAS SAAS006330

Sequence similarities

Belongs to the adenosine and AMP deaminases family. Adenosine deaminase subfamily. HAMAP MF_00540

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site2091Proton donor By similarity HAMAP MF_00540
Metal binding181Zinc; catalytic By similarity HAMAP MF_00540
Metal binding201Zinc; catalytic By similarity HAMAP MF_00540
Metal binding2061Zinc; catalytic By similarity HAMAP MF_00540
Metal binding2931Zinc; catalytic By similarity HAMAP MF_00540
Binding site201Substrate By similarity HAMAP MF_00540
Binding site221Substrate By similarity HAMAP MF_00540
Binding site1791Substrate; via amide nitrogen and carbonyl oxygen By similarity HAMAP MF_00540
Site2301Important for catalytic activity By similarity HAMAP MF_00540

Sequences

Sequence LengthMass (Da)Tools
Q82NX6 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: FFB6C91CD9B3F630

FASTA35438,203
        10         20         30         40         50         60 
MTALDIDTIR RLPKAVLHDH LDGGLRPATL VELAQAVGHT LPTTDPQALA DWYYEAANSG 

        70         80         90        100        110        120 
DLVRYIATFE HTLAVMQTRE GLLRTAEEYV LDLAADGVVY GEVRYAPELM LKGGLTLSEV 

       130        140        150        160        170        180 
VETVQEGLAA GMAKAAAAGT PVRVGTLLCG MRMFDRTRET ADLAVAFRDA GVVGFDIAGA 

       190        200        210        220        230        240 
EDGFPPADHL DAFEHLRREN VPFTIHAGEA HGLPSIHQAL QVCGAQRIGH GVRITEDIVD 

       250        260        270        280        290        300 
GKLGRLAGWV RDRRVALEMC PTSNLQTGAA TSIAEHPITA LKDLGFRVTL NTDNRLVSGT 

       310        320        330        340        350 
TMTREMSLLV EEAGWSTDDL RTVTVNALKS AFLPFDERNA LIQDVVLPGY EAAL

« Hide

References

[1]"Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis."
Ikeda H., Ishikawa J., Hanamoto A., Shinose M., Kikuchi H., Shiba T., Sakaki Y., Hattori M., Omura S.
Nat. Biotechnol. 21:526-531(2003) [PubMed: 12692562] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]"Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites."
Omura S., Ikeda H., Ishikawa J., Hanamoto A., Takahashi C., Shinose M., Takahashi Y., Horikawa H., Nakazawa H., Osonoe T., Kikuchi H., Shiba T., Sakaki Y., Hattori M.
Proc. Natl. Acad. Sci. U.S.A. 98:12215-12220(2001) [PubMed: 11572948] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 31267 / DSM 46492 / JCM 5070 / NCIMB 12804 / NRRL 8165.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BA000030 Genomic DNA. Translation: BAC68875.1.
RefSeqNP_822340.1. NC_003155.4.

3D structure databases

HSSPHSSP built from PDB template 1KRM based on UniProtKB P56658.
ProteinModelPortalQ82NX6.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1210149.
GenomeReviewsGene locus SAV1165 in contig BA000030_GR.
KEGGsma:SAV_1165.
NMPDRfig|227882.1.peg.1166.
PATRIC23715655. VBIStrAve112782_1245.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG630382.
OMAITLECCA.
ProtClustDBPRK09358.

Enzyme and pathway databases

BioCycSAVE227882:SAV1165-MONOMER.

Family and domain databases

HAMAPMF_00540. A_deaminase.
[Tree]
InterProIPR001365. A/AMP_deaminase_dom.
IPR006330. A_deaminase.
[Graphical view]
KOK01488.
PfamPF00962. A_deaminase. 1 hit.
[Graphical view]
TIGRFAMsTIGR01430. Aden_deam. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ82NX6_STRAW
AccessionPrimary (citable) accession number: Q82NX6
Entry history
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: December 14, 2011
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info