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Protein

Glutaminase

Gene

glsA

Organism
Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei73SubstrateUniRule annotation1
Binding sitei123SubstrateUniRule annotation1
Binding sitei167SubstrateUniRule annotation1
Binding sitei174SubstrateUniRule annotation1
Binding sitei198SubstrateUniRule annotation1
Binding sitei249SubstrateUniRule annotation1
Binding sitei267Substrate; via amide nitrogenUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
GlutaminaseUniRule annotation (EC:3.5.1.2UniRule annotation)
Gene namesi
Name:glsAUniRule annotation
Ordered Locus Names:SAV_1314
OrganismiStreptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)
Taxonomic identifieri227882 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomyces
Proteomesi
  • UP000000428 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001106261 – 313GlutaminaseAdd BLAST313

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi227882.SAV_1314.

Structurei

3D structure databases

ProteinModelPortaliQ82NI9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CSV. Bacteria.
COG2066. LUCA.
HOGENOMiHOG000216890.
KOiK01425.
OMAiANYMKSF.
OrthoDBiPOG091H02PU.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase. 1 hit.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q82NI9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVIMSASWSS HAFQPVLERI ADEIERTPGR GRPADYIPAL AACDPRRFGM
60 70 80 90 100
AVAELDGTVY GVGDWRQPFS TQSITKVFTL ALDLAREGDA LWEHVGREPS
110 120 130 140 150
GNPFNSLVQL EYESGIPRNP FINAGALVVT DRLQTQTGDA AGSLLEFLRA
160 170 180 190 200
ESGNPRLTFD QDVAASEAAH GDRNAALGHF MASYGNIDNS VPVLLDQYFR
210 220 230 240 250
QCSIEASCAD LALATGFLAR HGIRADGSRL LTQSQAKQVN AVMLTCGTYD
260 270 280 290 300
AAGDFAYRVG LPGKSGVGGG IIAVVPGRCT LCVWSPGLDE RGNSVAGVAA
310
LDRFTTLTGV SVF
Length:313
Mass (Da):33,299
Last modified:June 1, 2003 - v1
Checksum:iF77B2789DBC2781D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000030 Genomic DNA. Translation: BAC69024.1.
RefSeqiWP_010982752.1. NZ_JZJK01000078.1.

Genome annotation databases

EnsemblBacteriaiBAC69024; BAC69024; SAVERM_1314.
KEGGisma:SAV_1314.
PATRICi23715967. VBIStrAve112782_1401.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000030 Genomic DNA. Translation: BAC69024.1.
RefSeqiWP_010982752.1. NZ_JZJK01000078.1.

3D structure databases

ProteinModelPortaliQ82NI9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi227882.SAV_1314.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAC69024; BAC69024; SAVERM_1314.
KEGGisma:SAV_1314.
PATRICi23715967. VBIStrAve112782_1401.

Phylogenomic databases

eggNOGiENOG4105CSV. Bacteria.
COG2066. LUCA.
HOGENOMiHOG000216890.
KOiK01425.
OMAiANYMKSF.
OrthoDBiPOG091H02PU.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase. 1 hit.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiGLSA_STRAW
AccessioniPrimary (citable) accession number: Q82NI9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: June 1, 2003
Last modified: November 2, 2016
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.