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Protein

Alpha-galactosidase

Gene

agaB2

Organism
Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseUniRule annotation, Hydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Alpha-galactosidaseUniRule annotation (EC:3.2.1.22UniRule annotation)
Alternative name(s):
MelibiaseUniRule annotation
Gene namesi
Name:agaB2Imported
ORF Names:SAVERM_1475Imported
OrganismiStreptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)Imported
Taxonomic identifieri227882 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomyces
Proteomesi
  • UP000000428 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 45Sequence analysisAdd BLAST45
ChainiPRO_500429891546 – 682Alpha-galactosidaseSequence analysisAdd BLAST637

Keywords - PTMi

Disulfide bondUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi227882.SAV_1475.

Structurei

3D structure databases

ProteinModelPortaliQ82N28.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini537 – 682NPCBMInterPro annotationAdd BLAST146

Sequence similaritiesi

Belongs to the glycosyl hydrolase 27 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG4105EX0. Bacteria.
ENOG410XPF1. LUCA.
HOGENOMiHOG000161224.
KOiK07407.
OMAiNKPWEWA.
OrthoDBiPOG091H0DSB.

Family and domain databases

CDDicd14792. GH27. 1 hit.
Gene3Di2.60.40.10. 1 hit.
2.60.40.1180. 1 hit.
3.20.20.70. 1 hit.
InterProiIPR018905. A-galactase_NEW3.
IPR013785. Aldolase_TIM.
IPR008979. Galactose-bd-like.
IPR013222. Glyco_hyd_98_carb-bd.
IPR002241. Glyco_hydro_27.
IPR000111. Glyco_hydro_27/36_CS.
IPR013780. Glyco_hydro_b.
IPR017853. Glycoside_hydrolase_SF.
IPR013783. Ig-like_fold.
[Graphical view]
PfamiPF16499. Melibiase_2. 1 hit.
PF08305. NPCBM. 1 hit.
PF10633. NPCBM_assoc. 1 hit.
[Graphical view]
PRINTSiPR00740. GLHYDRLASE27.
SMARTiSM00776. NPCBM. 1 hit.
[Graphical view]
SUPFAMiSSF49785. SSF49785. 1 hit.
SSF51445. SSF51445. 1 hit.
PROSITEiPS00512. ALPHA_GALACTOSIDASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q82N28-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRHPYARTTR TTRTTRTTRR RVVGALTAGL LCTAGLAAPA LAAPAAGPVS
60 70 80 90 100
PRPADSLALT PPMGFNNWNS TGCRPEFNED MVKGTADIFV EKGLKDAGYQ
110 120 130 140 150
YVNLDDCWAL PARDSNGKLV PDPARFPGGI KAVADYVHSK GLKLGIYTSA
160 170 180 190 200
GTKTCNEAGF PGALGHEYSD AQQFADWGVD YLKYDNCNNQ GVDAKLRYTT
210 220 230 240 250
MRDALKATGR PIVYSLCEWG ENKPWEWASD VGQLWRTTGD ISDSWGSMLS
260 270 280 290 300
ILKQNLPLAP YAGPGHWNDP DMLEVGNSGM TDTEYRTHFS MWSIMAAPLL
310 320 330 340 350
IGSDLRKASA ATFDILDNKE VIAVDQDPLG KQGTVLSSEG GRWAVTKEMK
360 370 380 390 400
DGSRAVALFN ETDSAQRITT TAQAVGLPKA HAYTLRDLWQ HRSYNTAGTI
410 420 430 440 450
SATVPAHGTV LVRVSADAAW AKNPPAVELG VDGSPLLEAG RTVALTSALT
460 470 480 490 500
DLGRTPAKRV SVTLSGPRGW RVRATSPTTA GTVPTGRSLR TKWKVTAPDG
510 520 530 540 550
TAAGSYDLTL KATYRSPTGV RAETLVPLAA SVVPAPPSGV SYLGDLPWMS
560 570 580 590 600
TTNGWGPVER NTSNGESAAG DGRPITVDGV VHAKGIGVHA ESTIAYYTGR
610 620 630 640 650
SCETVTADVG VDDEQDTNGS VTFEIWADGT RVASTGVLTT AMPARPLSAD
660 670 680
VTGAQVVRLV VTDGGNGITS DHADWADAKL SC
Length:682
Mass (Da):72,330
Last modified:June 1, 2003 - v1
Checksum:iCE6AE06B08C99759
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000030 Genomic DNA. Translation: BAC69185.1.

Genome annotation databases

EnsemblBacteriaiBAC69185; BAC69185; SAVERM_1475.
KEGGisma:SAV_1475.
PATRICi23716315. VBIStrAve112782_1574.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000030 Genomic DNA. Translation: BAC69185.1.

3D structure databases

ProteinModelPortaliQ82N28.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi227882.SAV_1475.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAC69185; BAC69185; SAVERM_1475.
KEGGisma:SAV_1475.
PATRICi23716315. VBIStrAve112782_1574.

Phylogenomic databases

eggNOGiENOG4105EX0. Bacteria.
ENOG410XPF1. LUCA.
HOGENOMiHOG000161224.
KOiK07407.
OMAiNKPWEWA.
OrthoDBiPOG091H0DSB.

Family and domain databases

CDDicd14792. GH27. 1 hit.
Gene3Di2.60.40.10. 1 hit.
2.60.40.1180. 1 hit.
3.20.20.70. 1 hit.
InterProiIPR018905. A-galactase_NEW3.
IPR013785. Aldolase_TIM.
IPR008979. Galactose-bd-like.
IPR013222. Glyco_hyd_98_carb-bd.
IPR002241. Glyco_hydro_27.
IPR000111. Glyco_hydro_27/36_CS.
IPR013780. Glyco_hydro_b.
IPR017853. Glycoside_hydrolase_SF.
IPR013783. Ig-like_fold.
[Graphical view]
PfamiPF16499. Melibiase_2. 1 hit.
PF08305. NPCBM. 1 hit.
PF10633. NPCBM_assoc. 1 hit.
[Graphical view]
PRINTSiPR00740. GLHYDRLASE27.
SMARTiSM00776. NPCBM. 1 hit.
[Graphical view]
SUPFAMiSSF49785. SSF49785. 1 hit.
SSF51445. SSF51445. 1 hit.
PROSITEiPS00512. ALPHA_GALACTOSIDASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ82N28_STRAW
AccessioniPrimary (citable) accession number: Q82N28
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: November 2, 2016
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.