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Q82M90 (G6PI1_STRAW) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase 1

Short name=GPI 1
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase 1
Short name=PGI 1
Phosphohexose isomerase 1
Short name=PHI 1
Gene names
Name:pgi1
Ordered Locus Names:SAV_1770
OrganismStreptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NCIMB 12804 / NRRL 8165 / MA-4680) [Complete proteome] [HAMAP]
Taxonomic identifier227882 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces

Protein attributes

Sequence length549 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 549549Glucose-6-phosphate isomerase 1 HAMAP-Rule MF_00473
PRO_0000180747

Sites

Active site3581Proton donor By similarity
Active site3891 By similarity
Active site5131 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q82M90 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: B856B99B5D47BC19

FASTA54960,210
        10         20         30         40         50         60 
MSDSPRLTRR PEWTELEDHR AGPLLHPALR ELFAADPERA ERYVVRAGDL RLDYSKHLIT 

        70         80         90        100        110        120 
DETLALLQEL ATATDVFGLR DAMFRGEKIN VTENRAVLHT ALRAPRDAVI EVDGENVVPA 

       130        140        150        160        170        180 
VHAVLDRMAD FADRVRSGEW TGHTGSRIRT VVNIGIGGSD LGPAMAYEAL RAFTDRSLTV 

       190        200        210        220        230        240 
RFVSNVDGAD LHEAVRDLDP AETLFVIASK TFTTIETITN ATSARSWLLA GLDGDEKAVA 

       250        260        270        280        290        300 
KHFVALSTNA GKVSDFGIDT ANMFEFWDWV GGRYSFDSAI GLSLMIAIGP ERFRELLDGF 

       310        320        330        340        350        360 
RIVDEHFRTA PAEANAPLLL GLLGVWYGSF FGAQSHAVLP YSHYLSKFTA YLQQLDMESN 

       370        380        390        400        410        420 
GKSVDRDGHP VEWQTGPVVW GTPGTNGQHA YYQLLHQGTK VIPADLIGFI NPVDGLSDEL 

       430        440        450        460        470        480 
AAQHDLLMAN LFAQGQALAF GKTGDEVRAE GVPEEQVPHR TFRGNHPTTT ILAAELTPSV 

       490        500        510        520        530        540 
LGQLIALYEH KVFVQGAIWN IDSFDQWGVE LGKVLAKRVE PALTEGADVP GLDPSTAALV 


AAYRTHRKK 

« Hide

References

[1]"Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites."
Omura S., Ikeda H., Ishikawa J., Hanamoto A., Takahashi C., Shinose M., Takahashi Y., Horikawa H., Nakazawa H., Osonoe T., Kikuchi H., Shiba T., Sakaki Y., Hattori M.
Proc. Natl. Acad. Sci. U.S.A. 98:12215-12220(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 31267 / DSM 46492 / JCM 5070 / NCIMB 12804 / NRRL 8165 / MA-4680.
[2]"Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis."
Ikeda H., Ishikawa J., Hanamoto A., Shinose M., Kikuchi H., Shiba T., Sakaki Y., Hattori M., Omura S.
Nat. Biotechnol. 21:526-531(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 31267 / DSM 46492 / JCM 5070 / NCIMB 12804 / NRRL 8165 / MA-4680.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000030 Genomic DNA. Translation: BAC69481.1.
RefSeqNP_822946.1. NC_003155.4.

3D structure databases

ProteinModelPortalQ82M90.
SMRQ82M90. Positions 3-548.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING227882.SAV_1770.

Proteomic databases

PRIDEQ82M90.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAC69481; BAC69481; SAV_1770.
GeneID1210279.
KEGGsma:SAV_1770.
PATRIC23716941. VBIStrAve112782_1885.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000261370.
KOK01810.
OMAEWTELED.
OrthoDBEOG64R61J.
ProtClustDBPRK00179.

Enzyme and pathway databases

BioCycSAVE227882:GJU1-1781-MONOMER.
UniPathwayUPA00109; UER00181.

Family and domain databases

Gene3D1.10.1390.10. 1 hit.
HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI1_STRAW
AccessionPrimary (citable) accession number: Q82M90
Entry history
Integrated into UniProtKB/Swiss-Prot: March 29, 2005
Last sequence update: June 1, 2003
Last modified: February 19, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways