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Protein

Putative pterin-4-alpha-carbinolamine dehydratase

Gene

dcoH

Organism
Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

(6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin = (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin + H2O.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Lyase

Enzyme and pathway databases

BioCyciSAVE227882:GJU1-1870-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative pterin-4-alpha-carbinolamine dehydrataseUniRule annotation (EC:4.2.1.96UniRule annotation)
Short name:
PHSUniRule annotation
Alternative name(s):
4-alpha-hydroxy-tetrahydropterin dehydrataseUniRule annotation
Pterin carbinolamine dehydrataseUniRule annotation
Short name:
PCDUniRule annotation
Gene namesi
Name:dcoH
Ordered Locus Names:SAV_1858
OrganismiStreptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)
Taxonomic identifieri227882 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomyces
Proteomesi
  • UP000000428 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 101101Putative pterin-4-alpha-carbinolamine dehydratasePRO_0000063096Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi227882.SAV_1858.

Structurei

3D structure databases

ProteinModelPortaliQ82M02.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the pterin-4-alpha-carbinolamine dehydratase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG410842T. Bacteria.
COG2154. LUCA.
HOGENOMiHOG000007680.
KOiK01724.
OMAiHTHDAGG.
OrthoDBiEOG6S52NH.

Family and domain databases

Gene3Di3.30.1360.20. 1 hit.
HAMAPiMF_00434. Pterin_4_alpha.
InterProiIPR001533. Trans/pterin_deHydtase.
[Graphical view]
PANTHERiPTHR12599. PTHR12599. 1 hit.
PfamiPF01329. Pterin_4a. 1 hit.
[Graphical view]
SUPFAMiSSF55248. SSF55248. 1 hit.

Sequencei

Sequence statusi: Complete.

Q82M02-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPVEPLSQKE IEDRLAELPG WSLDGDRISR SYRLGSHFAA AAMVVHIAQV
60 70 80 90 100
QEELDHHSDL TLSYHTVSLT VNTHSVGGAV TELDFALARR VEDLAPGHGA

S
Length:101
Mass (Da):10,985
Last modified:June 1, 2003 - v1
Checksum:i920917D18E0ED02F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000030 Genomic DNA. Translation: BAC69569.1.
RefSeqiWP_010983297.1. NZ_JZJK01000086.1.

Genome annotation databases

EnsemblBacteriaiBAC69569; BAC69569; SAV_1858.
KEGGisma:SAV_1858.
PATRICi23717145. VBIStrAve112782_1986.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000030 Genomic DNA. Translation: BAC69569.1.
RefSeqiWP_010983297.1. NZ_JZJK01000086.1.

3D structure databases

ProteinModelPortaliQ82M02.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi227882.SAV_1858.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAC69569; BAC69569; SAV_1858.
KEGGisma:SAV_1858.
PATRICi23717145. VBIStrAve112782_1986.

Phylogenomic databases

eggNOGiENOG410842T. Bacteria.
COG2154. LUCA.
HOGENOMiHOG000007680.
KOiK01724.
OMAiHTHDAGG.
OrthoDBiEOG6S52NH.

Enzyme and pathway databases

BioCyciSAVE227882:GJU1-1870-MONOMER.

Family and domain databases

Gene3Di3.30.1360.20. 1 hit.
HAMAPiMF_00434. Pterin_4_alpha.
InterProiIPR001533. Trans/pterin_deHydtase.
[Graphical view]
PANTHERiPTHR12599. PTHR12599. 1 hit.
PfamiPF01329. Pterin_4a. 1 hit.
[Graphical view]
SUPFAMiSSF55248. SSF55248. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites."
    Omura S., Ikeda H., Ishikawa J., Hanamoto A., Takahashi C., Shinose M., Takahashi Y., Horikawa H., Nakazawa H., Osonoe T., Kikuchi H., Shiba T., Sakaki Y., Hattori M.
    Proc. Natl. Acad. Sci. U.S.A. 98:12215-12220(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680.
  2. "Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis."
    Ikeda H., Ishikawa J., Hanamoto A., Shinose M., Kikuchi H., Shiba T., Sakaki Y., Hattori M., Omura S.
    Nat. Biotechnol. 21:526-531(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680.

Entry informationi

Entry nameiPHS_STRAW
AccessioniPrimary (citable) accession number: Q82M02
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: June 1, 2003
Last modified: November 11, 2015
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.