ID   Q82LV8_STRAW            Unreviewed;       820 AA.
AC   Q82LV8;
DT   01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2003, sequence version 1.
DT   27-MAR-2024, entry version 124.
DE   RecName: Full=PAS domain-containing protein {ECO:0000259|PROSITE:PS50112};
GN   ORFNames=SAVERM_1902 {ECO:0000313|EMBL:BAC69613.1};
OS   Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC
OS   14893 / NCIMB 12804 / NRRL 8165 / MA-4680).
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=227882 {ECO:0000313|EMBL:BAC69613.1, ECO:0000313|Proteomes:UP000000428};
RN   [1] {ECO:0000313|EMBL:BAC69613.1, ECO:0000313|Proteomes:UP000000428}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 /
RC   NRRL 8165 / MA-4680 {ECO:0000313|Proteomes:UP000000428};
RX   PubMed=11572948; DOI=10.1073/pnas.211433198;
RA   Omura S., Ikeda H., Ishikawa J., Hanamoto A., Takahashi C., Shinose M.,
RA   Takahashi Y., Horikawa H., Nakazawa H., Osonoe T., Kikuchi H., Shiba T.,
RA   Sakaki Y., Hattori M.;
RT   "Genome sequence of an industrial microorganism Streptomyces avermitilis:
RT   deducing the ability of producing secondary metabolites.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:12215-12220(2001).
RN   [2] {ECO:0000313|EMBL:BAC69613.1, ECO:0000313|Proteomes:UP000000428}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 /
RC   NRRL 8165 / MA-4680 {ECO:0000313|Proteomes:UP000000428};
RX   PubMed=12692562; DOI=10.1038/nbt820;
RA   Ikeda H., Ishikawa J., Hanamoto A., Shinose M., Kikuchi H., Shiba T.,
RA   Sakaki Y., Hattori M., Omura S.;
RT   "Complete genome sequence and comparative analysis of the industrial
RT   microorganism Streptomyces avermitilis.";
RL   Nat. Biotechnol. 21:526-531(2003).
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DR   EMBL; BA000030; BAC69613.1; -; Genomic_DNA.
DR   RefSeq; WP_010983341.1; NZ_JZJK01000086.1.
DR   AlphaFoldDB; Q82LV8; -.
DR   KEGG; sma:SAVERM_1902; -.
DR   eggNOG; COG2203; Bacteria.
DR   eggNOG; COG2208; Bacteria.
DR   HOGENOM; CLU_000445_43_3_11; -.
DR   OrthoDB; 118142at2; -.
DR   Proteomes; UP000000428; Chromosome.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd16936; HATPase_RsbW-like; 1.
DR   CDD; cd00130; PAS; 1.
DR   Gene3D; 3.30.450.40; -; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   InterPro; IPR003018; GAF.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013767; PAS_fold.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   PANTHER; PTHR43156:SF2; MULTIDOMAIN REGULATORY PROTEIN RV1364C; 1.
DR   PANTHER; PTHR43156; STAGE II SPORULATION PROTEIN E-RELATED; 1.
DR   Pfam; PF01590; GAF; 1.
DR   Pfam; PF13581; HATPase_c_2; 1.
DR   Pfam; PF00989; PAS; 1.
DR   Pfam; PF07228; SpoIIE; 1.
DR   SMART; SM00331; PP2C_SIG; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   SUPFAM; SSF55781; GAF domain-like; 1.
DR   SUPFAM; SSF81606; PP2C-like; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR   PROSITE; PS50112; PAS; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000000428}.
FT   DOMAIN          33..66
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
SQ   SEQUENCE   820 AA;  88596 MW;  CF252E68F02274FB CRC64;
     MERGTEWGAP SGHGAGHGAV ERATAAGRIP LAVVVVDRAG LVSHWSRGAR RLFGTSREDA
     VGRPAVDLLP VSGALPDDEI APYGAYAAYE GLGPDLESSL GGWLSYPAAG RARLRVPERD
     RIDVLWWAYP LVGPGPERLL VLAADADALR PDARGAEGVA VERIAPGFAL HTDFPGAEEL
     ARELPEILPS MSVGESARIV SQVLELGYPV LEFSQNDRVP VTPDWGVPRR AERKARRERA
     ARAVASGESV PQDVQDEGED LEYVAVRERL EFLNEVSGRI GTSLDLAQTI IEVSKAVVPR
     FTDVAGTYLR EQVVAGEGFP DGVPDTTTMW HRVAVEHTDE PGRWDDVVPV GEAMPFPAHT
     PFFQCMTSGQ PVLVPRISEQ MGHAIAAQFE KRDIRPLINN RSMLVVPLKA RNVVLGFMIL
     LRHPERVEFN DMDRVTGAEL AARAGLVLDN ARMYTYQESV AETLQDSMLP HIAPRMAGCD
     IATRYLPGTL LGRVGGDWFD SVKLPGSRTA LVVGDVMGHG LNSAAMMGQL RTAVQTMAAL
     DLPPAQLLRN LDDLAQRLGD TYLATCLYAV YDPITSELEI ANAGHIPPVL VRAEDGRSEL
     LDLPTGAPIG VGGVPFESVR VPVAPGDRLV MCTDGLVEVR GEDIGVGLAT LCESAAHPAA
     SMDDACDTII RALNVRGGRK DDVALLMARL GGIAPEDVAL WRFALDPVEV GRARAAVREQ
     LHEWGLNSLA DNAELMVGEL VTNAVRHARS RRVELRLVRG ETLLCEVDDE DHTLPSLRGA
     GPADEFGRGL RVVSTLAREW GASRTSAGKT VWFELTLPRR
//