ID   Q82L80_STRAW            Unreviewed;       451 AA.
AC   Q82L80;
DT   01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 2.
DT   24-JAN-2024, entry version 137.
DE   RecName: Full=sulfate adenylyltransferase {ECO:0000256|ARBA:ARBA00012391};
DE            EC=2.7.7.4 {ECO:0000256|ARBA:ARBA00012391};
GN   Name=cysN1 {ECO:0000313|EMBL:BAC69843.2};
GN   ORFNames=SAVERM_2132 {ECO:0000313|EMBL:BAC69843.2};
OS   Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC
OS   14893 / NCIMB 12804 / NRRL 8165 / MA-4680).
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=227882 {ECO:0000313|EMBL:BAC69843.2, ECO:0000313|Proteomes:UP000000428};
RN   [1] {ECO:0000313|EMBL:BAC69843.2, ECO:0000313|Proteomes:UP000000428}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 /
RC   NRRL 8165 / MA-4680 {ECO:0000313|Proteomes:UP000000428};
RX   PubMed=11572948; DOI=10.1073/pnas.211433198;
RA   Omura S., Ikeda H., Ishikawa J., Hanamoto A., Takahashi C., Shinose M.,
RA   Takahashi Y., Horikawa H., Nakazawa H., Osonoe T., Kikuchi H., Shiba T.,
RA   Sakaki Y., Hattori M.;
RT   "Genome sequence of an industrial microorganism Streptomyces avermitilis:
RT   deducing the ability of producing secondary metabolites.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:12215-12220(2001).
RN   [2] {ECO:0000313|EMBL:BAC69843.2, ECO:0000313|Proteomes:UP000000428}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 /
RC   NRRL 8165 / MA-4680 {ECO:0000313|Proteomes:UP000000428};
RX   PubMed=12692562; DOI=10.1038/nbt820;
RA   Ikeda H., Ishikawa J., Hanamoto A., Shinose M., Kikuchi H., Shiba T.,
RA   Sakaki Y., Hattori M., Omura S.;
RT   "Complete genome sequence and comparative analysis of the industrial
RT   microorganism Streptomyces avermitilis.";
RL   Nat. Biotechnol. 21:526-531(2003).
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DR   EMBL; BA000030; BAC69843.2; -; Genomic_DNA.
DR   RefSeq; WP_062804690.1; NC_003155.5.
DR   AlphaFoldDB; Q82L80; -.
DR   KEGG; sma:SAVERM_2132; -.
DR   eggNOG; COG2895; Bacteria.
DR   Proteomes; UP000000428; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0004781; F:sulfate adenylyltransferase (ATP) activity; IEA:UniProtKB-EC.
DR   GO; GO:0006790; P:sulfur compound metabolic process; IEA:InterPro.
DR   CDD; cd04166; CysN_ATPS; 1.
DR   CDD; cd03695; CysN_NodQ_II; 1.
DR   CDD; cd04095; CysN_NoDQ_III; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 2.40.30.10; Translation factors; 2.
DR   InterPro; IPR041757; CysN_GTP-bd.
DR   InterPro; IPR044138; CysN_II.
DR   InterPro; IPR044139; CysN_NoDQ_III.
DR   InterPro; IPR031157; G_TR_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR011779; SO4_adenylTrfase_lsu.
DR   InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR   InterPro; IPR009000; Transl_B-barrel_sf.
DR   InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR   NCBIfam; TIGR02034; CysN; 1.
DR   PANTHER; PTHR23115:SF170; ELONGATION FACTOR 1-ALPHA 2; 1.
DR   PANTHER; PTHR23115; TRANSLATION FACTOR; 1.
DR   Pfam; PF00009; GTP_EFTU; 1.
DR   PRINTS; PR00315; ELONGATNFCT.
DR   SUPFAM; SSF50465; EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF50447; Translation proteins; 1.
DR   PROSITE; PS00301; G_TR_1; 1.
DR   PROSITE; PS51722; G_TR_2; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695,
KW   ECO:0000313|EMBL:BAC69843.2};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000428};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          19..231
FT                   /note="Tr-type G"
FT                   /evidence="ECO:0000259|PROSITE:PS51722"
SQ   SEQUENCE   451 AA;  48148 MW;  818A21248A0BF551 CRC64;
     MTSTTEPTEP LSVEQLSATT LLRFATAGSV DDGKSTLVGR LLHDSKSVLT DQLEAVEQVS
     RSRGQDAPDL ALLTDGLRAE REQGITIDVA YRYFATARRR FILADTPGHV QYTRNMVTGA
     STADLAVVLV DARNGVIEQT RRHAAVAALL RVPHVVLAVN KMDLVEYKES VFAAIAEKFT
     AYASELGVPE ITAIPISALA GDNVVDASAN MDWYGGPTVL EHLETVPVSH DLAHCHARLP
     VQYVIRPQTA EHPDYRGYAG QIAAGTFCVG SEVTVLPSGR TSKIAGIDLL GTPVDVAWTP
     QSVTLLLEDD IDISRGDLLV PSKDAPATTQ DVEATVCHVA DAPLTVGHRV LLKHGTRTVK
     AIVKDIPSRL TLDDLSLAPA PGQLVANDIG RVKIRTAEPL PLDSYADSRR TGAFILIDPA
     DGTTLTAGMV GESFAAPEPV KDASDDDGWD F
//