ID   Q82K90_STRAW            Unreviewed;       915 AA.
AC   Q82K90;
DT   01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2003, sequence version 1.
DT   27-MAR-2024, entry version 119.
DE   SubName: Full=Osmitic regulatory protein(PrpM2, magnesium or manganese-dependent protein phosphatase) {ECO:0000313|EMBL:BAC70224.1};
GN   Name=osaC {ECO:0000313|EMBL:BAC70224.1};
GN   ORFNames=SAVERM_2513 {ECO:0000313|EMBL:BAC70224.1};
OS   Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC
OS   14893 / NCIMB 12804 / NRRL 8165 / MA-4680).
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=227882 {ECO:0000313|EMBL:BAC70224.1, ECO:0000313|Proteomes:UP000000428};
RN   [1] {ECO:0000313|EMBL:BAC70224.1, ECO:0000313|Proteomes:UP000000428}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 /
RC   NRRL 8165 / MA-4680 {ECO:0000313|Proteomes:UP000000428};
RX   PubMed=11572948; DOI=10.1073/pnas.211433198;
RA   Omura S., Ikeda H., Ishikawa J., Hanamoto A., Takahashi C., Shinose M.,
RA   Takahashi Y., Horikawa H., Nakazawa H., Osonoe T., Kikuchi H., Shiba T.,
RA   Sakaki Y., Hattori M.;
RT   "Genome sequence of an industrial microorganism Streptomyces avermitilis:
RT   deducing the ability of producing secondary metabolites.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:12215-12220(2001).
RN   [2] {ECO:0000313|EMBL:BAC70224.1, ECO:0000313|Proteomes:UP000000428}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 /
RC   NRRL 8165 / MA-4680 {ECO:0000313|Proteomes:UP000000428};
RX   PubMed=12692562; DOI=10.1038/nbt820;
RA   Ikeda H., Ishikawa J., Hanamoto A., Shinose M., Kikuchi H., Shiba T.,
RA   Sakaki Y., Hattori M., Omura S.;
RT   "Complete genome sequence and comparative analysis of the industrial
RT   microorganism Streptomyces avermitilis.";
RL   Nat. Biotechnol. 21:526-531(2003).
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DR   EMBL; BA000030; BAC70224.1; -; Genomic_DNA.
DR   RefSeq; WP_010983950.1; NZ_JZJK01000086.1.
DR   AlphaFoldDB; Q82K90; -.
DR   DNASU; 1213837; -.
DR   KEGG; sma:SAVERM_2513; -.
DR   eggNOG; COG2172; Bacteria.
DR   eggNOG; COG2203; Bacteria.
DR   eggNOG; COG2208; Bacteria.
DR   HOGENOM; CLU_014270_0_0_11; -.
DR   OrthoDB; 9807247at2; -.
DR   Proteomes; UP000000428; Chromosome.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd16936; HATPase_RsbW-like; 1.
DR   CDD; cd00130; PAS; 1.
DR   Gene3D; 3.30.450.40; -; 2.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   InterPro; IPR003018; GAF.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013767; PAS_fold.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   NCBIfam; TIGR00229; sensory_box; 1.
DR   PANTHER; PTHR43156:SF2; MULTIDOMAIN REGULATORY PROTEIN RV1364C; 1.
DR   PANTHER; PTHR43156; STAGE II SPORULATION PROTEIN E-RELATED; 1.
DR   Pfam; PF13185; GAF_2; 1.
DR   Pfam; PF13492; GAF_3; 1.
DR   Pfam; PF13581; HATPase_c_2; 1.
DR   Pfam; PF00989; PAS; 1.
DR   Pfam; PF07228; SpoIIE; 1.
DR   SMART; SM00065; GAF; 2.
DR   SMART; SM00091; PAS; 1.
DR   SMART; SM00331; PP2C_SIG; 1.
DR   SUPFAM; SSF55781; GAF domain-like; 2.
DR   SUPFAM; SSF81606; PP2C-like; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR   PROSITE; PS50112; PAS; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000000428}.
FT   DOMAIN          202..232
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   REGION          1..24
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   915 AA;  97387 MW;  96DF9D9782BCF136 CRC64;
     MTTGLHPGGP PQDPRPTGNQ PLPRQERVGE AALHADNRTR SSVITARAAA SFDPVGRSVA
     TARSFVRDTL QGWGFADIVD DAVVLTSELV TNAVVHAGTS ADVLCLRSDD GVRIEVGDRY
     PEREIPLQAA AVNMGNPDRE GGRGLQLCAA LAGRWGVDYT PTHKQVWFQL DLPERPVGTR
     TAGPSLPAEL LPLADGRVRV AVVQIDRAGA INAWNEDAEE LFGYAAELVI GKPLTDLAAW
     PHTPGTSTGI VEALQLSRWE GSYGVRGASG RVIPVYASHL RVRDTGGEPS TVCLLVREHE
     RAVLQTPLRG QSPDATNSAE GQALDPFEVF IGSPAPDDLD GLLQRTVERA RDMLDADSAF
     LLLATDDETE LEVRASTGLP SARQRFARVP VDAGPGRYGS ARMPAVHDDL TAVPGAVPLL
     SGTGMRSVVT VPLKVEGRLT GSLGVAAESP SRYSNEEALR LQFAADRIAL AVESARLGEL
     ERLRRGSLSF LVEASDLLAG TLDRDQTLAL MAQMTIPTLA TWCAVYTIAD QASEPYLSYV
     LHEDEDRIDG VKALLSKIPP PEPIPTPGAR VWSAPAQAAH EAALRTSMRS LGLGEPATVS
     SGIGTTLATA SAVGGETVVL PLVARNRVIG MLTLGKPSDE HFRQEILELA EDLSRRAALA
     LDNARLYSER TAISQSLQRS LLPPDLPHIE GVEVEVIYRA AGEGNEVGGD FYDLFPIRDG
     AYGFAIGDVC GTGPNAAAVT GLARHALRLL AREGLSGPAV LERLNSAILD EGARSRFLTL
     LYGELWPQED GSALLKVVCA GHPLPLRLRQ DGTVEPAAEP QPLLGVMEDL ELYEQTVTLD
     PGDVLLCVTD GVTERREGTR MLGDDGLTDV LTTCTGLTAG AVAARIMRAV ERFASDAPSD
     DMAILAMRVA GLQKD
//