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Protein
Submitted name:

Putative 4-aminobutyrate aminotransferase

Gene

gabT

Organism
Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NCIMB 12804 / NRRL 8165 / MA-4680)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. 4-aminobutyrate transaminase activity Source: InterPro
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. gamma-aminobutyric acid metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

AminotransferaseImported, Transferase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciSAVE227882:GJU1-2599-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Putative 4-aminobutyrate aminotransferaseImported
Gene namesi
Name:gabTImported
Ordered Locus Names:SAV_2583Imported
OrganismiStreptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NCIMB 12804 / NRRL 8165 / MA-4680)Imported
Taxonomic identifieri227882 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces
ProteomesiUP000000428: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi227882.SAV_2583.

Structurei

3D structure databases

ProteinModelPortaliQ82K21.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000020206.
KOiK07250.
OMAiCGKAEIM.
OrthoDBiEOG6QVRHN.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR004632. 4NH2But_aminotransferase_bac.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11986. PTHR11986. 1 hit.
PfamiPF00202. Aminotran_3. 1 hit.
[Graphical view]
PIRSFiPIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR00700. GABAtrnsam. 1 hit.
PROSITEiPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q82K21-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MSALPQERRV VTAIPGPKSQ ELQARRTAVV AAGVGSVLPV FTTRAGGGII
60 70 80 90 100
EDVDGNRLID FGSGIAVTSV GASAEAVVRR ASAQLQDFTH TCFMVTPYEG
110 120 130 140 150
YVAVAEALAE LTPGDHAKKS ALFNSGAEAV ENAVKIARAY TKRQAVVVFD
160 170 180 190 200
HGYHGRTNLT MALTAKNMPY KNGFGPFAPE VYRVPVAYGY RWLTGPENAG
210 220 230 240 250
AEASAQAIDM INKQIGADNV AAIIIEPVLG EGGFIEPAKG FLPAISKFAK
260 270 280 290 300
DNGIVFVADE IQSGFCRTGQ WFACEDEGIV PDLITTAKGI AGGLPLAAVT
310 320 330 340 350
GRAEIMDAAH AGGLGGTYGG NPVACAGALG AIETMKELDL NAKAKNIEAV
360 370 380 390 400
MKARLGAMAE KFDIIGDVRG RGGMIAIELV KDRDTKEPNP EAAGALAKAC
410 420 430 440
HQEGLLVLTC GTYGNVLRFL PPLVIGEDLL NEGLDIIEQA FSRI
Length:444
Mass (Da):46,470
Last modified:June 1, 2003 - v1
Checksum:i8D2F6E5C455695EC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000030 Genomic DNA. Translation: BAC70294.1.
RefSeqiNP_823759.1. NC_003155.4.

Genome annotation databases

EnsemblBacteriaiBAC70294; BAC70294; SAV_2583.
GeneIDi1210475.
KEGGisma:SAV_2583.
PATRICi23718697. VBIStrAve112782_2762.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000030 Genomic DNA. Translation: BAC70294.1.
RefSeqiNP_823759.1. NC_003155.4.

3D structure databases

ProteinModelPortaliQ82K21.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi227882.SAV_2583.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAC70294; BAC70294; SAV_2583.
GeneIDi1210475.
KEGGisma:SAV_2583.
PATRICi23718697. VBIStrAve112782_2762.

Phylogenomic databases

HOGENOMiHOG000020206.
KOiK07250.
OMAiCGKAEIM.
OrthoDBiEOG6QVRHN.

Enzyme and pathway databases

BioCyciSAVE227882:GJU1-2599-MONOMER.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR004632. 4NH2But_aminotransferase_bac.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11986. PTHR11986. 1 hit.
PfamiPF00202. Aminotran_3. 1 hit.
[Graphical view]
PIRSFiPIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR00700. GABAtrnsam. 1 hit.
PROSITEiPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites."
    Omura S., Ikeda H., Ishikawa J., Hanamoto A., Takahashi C., Shinose M., Takahashi Y., Horikawa H., Nakazawa H., Osonoe T., Kikuchi H., Shiba T., Sakaki Y., Hattori M.
    Proc. Natl. Acad. Sci. U.S.A. 98:12215-12220(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 31267 / DSM 46492 / JCM 5070 / NCIMB 12804 / NRRL 8165 / MA-4680Imported.
  2. "Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis."
    Ikeda H., Ishikawa J., Hanamoto A., Shinose M., Kikuchi H., Shiba T., Sakaki Y., Hattori M., Omura S.
    Nat. Biotechnol. 21:526-531(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiQ82K21_STRAW
AccessioniPrimary (citable) accession number: Q82K21
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: January 7, 2015
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.