Q82JN1 (Q82JN1_STRAW) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Putative delta-1-pyrroline-5-carboxylate dehydrogenase EMBL BAC70434.1

Gene names

Name:	rocA EMBL BAC70434.1
Ordered Locus Names:	SAV_2723 EMBL BAC70434.1

Organism

Streptomyces avermitilis [Complete proteome] [HAMAP]

Taxonomic identifier

33903 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Streptomycineae › Streptomycetaceae › Streptomyces

Protein attributes

Sequence length	543 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the aldehyde dehydrogenase family. RuleBase RU003345

Ontologies

Keywords
Molecular function	Oxidoreductase RuleBase RU003344
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proline biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	mitochondrial matrix Inferred from electronic annotation. Source: InterPro
Molecular function	1-pyrroline-5-carboxylate dehydrogenase activity Inferred from electronic annotation. Source: InterPro oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q82JN1 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: 7D3682AFC5FC9F84	FASTA	543	58,980
	10 20 30 40 50 60 MDAVTQVPTP VNEPVHGYAP GSPERARLEA KLKELAENPI ELPMTIGGEK RLGGGERFEV 70 80 90 100 110 120 VQPHNHKAVI GTGAHATQQD AQDAIDAALA AAPAWRAMSF DDRAAIILRA AELLSGPWRE 130 140 150 160 170 180 TLAASTMLGQ SKTAQQAEID CPCELVDFWR FNVKYARDLL AEQPPANSPG VWNRLDHRPL 190 200 210 220 230 240 EGFVYAITPF NFSAIAGNLP TAPALMGNVV VWKPSPTQTH AAVLLMRLLE EAGLPKGVIN 250 260 270 280 290 300 LVTGDGIEVS KVALEHRDLA GIHFTGSTKT FQYLWKTVGN NIEKYRSYPR LVGETGGKDF 310 320 330 340 350 360 LVAHPSADRA VLKTALTRGA FEYQGQKCSA TSRAYLPASI WNSGFKEEFA AEVDYLTMGD 370 380 390 400 410 420 VTDLSNFVGA VIDERSFAKN KAAIDRAKSD PTCTIVAGGE YDDSVGYFVR PTVVECSDPE 430 440 450 460 470 480 NEVFKTEYFG PFLAVHVYED DAYDEMLTQM ESASDYALTG AVVSNDRAAA AYTMDKLRYA 490 500 510 520 530 540 AGNFYINDKS TGAVVGQQPF GGGRASGTND KAGAPQNLMR WTLTRAIKET LVPPTDYTYP HMG

References

[1]

"Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis." Ikeda H., Ishikawa J., Hanamoto A., Shinose M., Kikuchi H., Shiba T., Sakaki Y., Hattori M., Omura S. Nat. Biotechnol. 21:526-531(2003) [PubMed: 12692562] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

[2]

"Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites." Omura S., Ikeda H., Ishikawa J., Hanamoto A., Takahashi C., Shinose M., Takahashi Y., Horikawa H., Nakazawa H., Osonoe T., Kikuchi H., Shiba T., Sakaki Y., Hattori M. Proc. Natl. Acad. Sci. U.S.A. 98:12215-12220(2001) [PubMed: 11572948] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 31267 / DSM 46492 / JCM 5070 / NCIMB 12804 / NRRL 8165.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000030 Genomic DNA. Translation: BAC70434.1.
RefSeq	NP_823899.1. NC_003155.4.
3D structure databases
ProteinModelPortal	Q82JN1.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1213972.
GenomeReviews	Gene locus SAV2723 in contig BA000030_GR.
KEGG	sma:SAV_2723.
NMPDR	fig|227882.1.peg.2725.
PATRIC	23719013. VBIStrAve112782_2916.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG752218.
OMA	CELVDFW.
ProtClustDB	CLSK871904.
Enzyme and pathway databases
BioCyc	SAVE227882:SAV2723-MONOMER.
Family and domain databases
InterPro	IPR016161. Ald_DH/histidinol_DH. IPR016163. Ald_DH_C. IPR016160. Ald_DH_CS. IPR016162. Ald_DH_N. IPR015590. Aldehyde_DH_dom. IPR005931. Delta1-pyrroline-5-COlate_DH-1. [Graphical view]
Gene3D	G3DSA:3.40.309.10. Aldehyde_dehydrogenase_C. 1 hit. G3DSA:3.40.605.10. Aldehyde_dehydrogenase_N. 1 hit.
KO	K00294.
Pfam	PF00171. Aldedh. 1 hit. [Graphical view]
SUPFAM	SSF53720. Aldehyde_DH/Histidinol_DH. 1 hit.
TIGRFAMs	TIGR01236. D1pyr5carbox1. 1 hit.
PROSITE	PS00070. ALDEHYDE_DEHYDR_CYS. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q82JN1_STRAW

Accession

Primary (citable) accession number: Q82JN1

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2003
Last sequence update:	June 1, 2003
Last modified:	December 14, 2011
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)