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Protein

1,4-alpha-glucan branching enzyme GlgB 1

Gene

glgB1

Organism
Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.UniRule annotation

Catalytic activityi

Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain.UniRule annotation

Pathwayi: glycogen biosynthesis

This protein is involved in the pathway glycogen biosynthesis, which is part of Glycan biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway glycogen biosynthesis and in Glycan biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei513NucleophileUniRule annotation1
Active sitei566Proton donorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferase, Transferase
Biological processCarbohydrate metabolism, Glycogen biosynthesis, Glycogen metabolism

Enzyme and pathway databases

UniPathwayiUPA00164

Protein family/group databases

CAZyiCBM48 Carbohydrate-Binding Module Family 48
GH13 Glycoside Hydrolase Family 13

Names & Taxonomyi

Protein namesi
Recommended name:
1,4-alpha-glucan branching enzyme GlgB 1UniRule annotation (EC:2.4.1.18UniRule annotation)
Alternative name(s):
1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase 1UniRule annotation
Alpha-(1->4)-glucan branching enzyme 1UniRule annotation
Glycogen branching enzyme 1UniRule annotation
Short name:
BE 1UniRule annotation
Gene namesi
Name:glgB1UniRule annotation
Ordered Locus Names:SAV_2805
OrganismiStreptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)
Taxonomic identifieri227882 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomyces
Proteomesi
  • UP000000428 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001887471 – 8381,4-alpha-glucan branching enzyme GlgB 1Add BLAST838

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi227882.SAV_2805

Structurei

3D structure databases

ProteinModelPortaliQ82JF0
SMRiQ82JF0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C9C Bacteria
COG0296 LUCA
HOGENOMiHOG000283037
KOiK00700
OMAiEVVHGKS
OrthoDBiPOG091H08D1

Family and domain databases

Gene3Di2.60.40.101 hit
2.60.40.11801 hit
HAMAPiMF_00685 GlgB, 1 hit
InterProiView protein in InterPro
IPR006048 A-amylase/branching_C
IPR037439 Branching_enzy
IPR006407 GlgB
IPR006047 Glyco_hydro_13_cat_dom
IPR004193 Glyco_hydro_13_N
IPR013780 Glyco_hydro_b
IPR017853 Glycoside_hydrolase_SF
IPR013783 Ig-like_fold
IPR014756 Ig_E-set
PANTHERiPTHR43651 PTHR43651, 2 hits
PfamiView protein in Pfam
PF00128 Alpha-amylase, 1 hit
PF02806 Alpha-amylase_C, 1 hit
PF02922 CBM_48, 1 hit
PIRSFiPIRSF000463 GlgB, 1 hit
SMARTiView protein in SMART
SM00642 Aamy, 1 hit
SUPFAMiSSF51445 SSF51445, 1 hit
SSF81296 SSF81296, 1 hit
TIGRFAMsiTIGR01515 branching_enzym, 1 hit

Sequencei

Sequence statusi: Complete.

Q82JF0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIPRPPSDDR ANQNGDGSKK TGAKKTGAKK AAAAKKTAGK KATPAAKATA
60 70 80 90 100
AKGAVTKKTG KGKATAKKAV ADKAAAKATV PQQAVPKQAV SKRAVSKKAV
110 120 130 140 150
PRKAVVKAAL DIPEAPVSPA VAPDDRDRLL SGTHHAPHSV LGAHPVPGGV
160 170 180 190 200
AFRVLRPYAL SVTVVTDDLR TELHDDGAGF FTGLLPLRAV PDYRLHVAYE
210 220 230 240 250
GTVHETEDAY RFLPALGELD LHLINEGRHE ELWTALGAEP MTHQGVPGTR
260 270 280 290 300
FTVWAPNARG VRLAGTFNFW DATAFPLRSL GSSGVWELFV PGVGEGELYK
310 320 330 340 350
FEITRPDGSK TLRADPVARR TEAPPRTSSI VHASHYAWAD EAWMAARGER
360 370 380 390 400
PVHESPFSVY EVHLPSWRPG LTYRQLAEQL PAYVADLGFT HVELLPVAEH
410 420 430 440 450
PFGGSWGYQV TGFYAPTARL GTPDDFKYLV DALHRAGVGV LMDWVPAHFP
460 470 480 490 500
RDDWALAEFD GRPLYEHEDP LRAAHPDWGT LEFDYGRREV RNFLVANAVY
510 520 530 540 550
WCEEFHIDGL RVDAVASMLY LDYSREEGQW SPNEFGGREN LDAVAFLQEM
560 570 580 590 600
NATVYRRVPG VVTIAEESTA WEGVTRATHD NGLGFGLKWN MGWMHDSLGY
610 620 630 640 650
VQHEPVHRRF HHHEMTFSMV YAYSENYVLP ISHDEVVHGK GSLVSKMPGD
660 670 680 690 700
WWQQRATERA YLGFMWAHPG KQLLFMGQEF AQGAEWSETH GPDWWLLDPA
710 720 730 740 750
YGAEPDHRGM RDLVRDLNTV YRHEPALWER DTDPSGFAWV TGDAVEDNVF
760 770 780 790 800
AFLRHAADGT PLLAVSNFSP VVRHDYRLGV PDDIPAWHET LNTDGARYGG
810 820 830
SDVTNPHPVK PEPQGRHGRP ASIRLTLPPL STLWLRPA
Length:838
Mass (Da):92,740
Last modified:June 1, 2003 - v1
Checksum:i3BFDF6B6AD3869CE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000030 Genomic DNA Translation: BAC70516.1

Genome annotation databases

EnsemblBacteriaiBAC70516; BAC70516; SAVERM_2805
KEGGisma:SAVERM_2805

Similar proteinsi

Entry informationi

Entry nameiGLGB1_STRAW
AccessioniPrimary (citable) accession number: Q82JF0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 15, 2003
Last sequence update: June 1, 2003
Last modified: February 28, 2018
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome