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Q82JD2

- PTA_STRAW

UniProt

Q82JD2 - PTA_STRAW

Protein

Phosphate acetyltransferase

Gene

pta

Organism
Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NCIMB 12804 / NRRL 8165 / MA-4680)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 66 (01 Oct 2014)
      Sequence version 1 (01 Jun 2003)
      Previous versions | rss
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    Functioni

    Involved in acetate metabolism.By similarity

    Catalytic activityi

    Acetyl-CoA + phosphate = CoA + acetyl phosphate.

    Pathwayi

    GO - Molecular functioni

    1. phosphate acetyltransferase activity Source: UniProtKB-EC

    GO - Biological processi

    1. acetyl-CoA biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Acyltransferase, Transferase

    Enzyme and pathway databases

    BioCyciSAVE227882:GJU1-2844-MONOMER.
    UniPathwayiUPA00340; UER00459.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphate acetyltransferase (EC:2.3.1.8)
    Alternative name(s):
    Phosphotransacetylase
    Gene namesi
    Name:pta
    Ordered Locus Names:SAV_2823
    OrganismiStreptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NCIMB 12804 / NRRL 8165 / MA-4680)
    Taxonomic identifieri227882 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces
    ProteomesiUP000000428: Chromosome

    Subcellular locationi

    Cytoplasm Curated

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 696696Phosphate acetyltransferasePRO_0000405552Add
    BLAST

    Proteomic databases

    PRIDEiQ82JD2.

    Interactioni

    Protein-protein interaction databases

    STRINGi227882.SAV_2823.

    Structurei

    3D structure databases

    ProteinModelPortaliQ82JD2.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni367 – 696330Phosphate acetyltransferaseAdd
    BLAST

    Domaini

    The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site By similarity.By similarity

    Sequence similaritiesi

    In the N-terminal section; belongs to the CobB/CobQ family.Curated
    In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.Curated

    Phylogenomic databases

    eggNOGiCOG0280.
    HOGENOMiHOG000053797.
    KOiK13788.
    OMAiATIRPAF.
    OrthoDBiEOG6BKJ5W.

    Family and domain databases

    Gene3Di3.40.1390.20. 1 hit.
    3.40.50.300. 1 hit.
    InterProiIPR010766. DRTGG.
    IPR016475. P-Actrans_bac.
    IPR027417. P-loop_NTPase.
    IPR004614. P_AcTrfase.
    IPR002505. PTA_PTB.
    IPR028979. Ser_kin/Pase_Hpr_N_like.
    [Graphical view]
    PfamiPF07085. DRTGG. 1 hit.
    PF01515. PTA_PTB. 1 hit.
    [Graphical view]
    PIRSFiPIRSF006107. PhpActrans_proteobac. 1 hit.
    SUPFAMiSSF52540. SSF52540. 1 hit.
    SSF75138. SSF75138. 1 hit.
    TIGRFAMsiTIGR00651. pta. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q82JD2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTRSVYVTGI DRGDGRQVVE LGVMELLTRQ VDRVGVFRPL VHDGPDRLFE    50
    LLRARYRLAQ DPATVYGMDY HEASALQAEQ GTDELMSTLV DRFHLVARDY 100
    DVVLVLGTDF ADTQFPDELA LNARLANEFG AAVIPVVGGR GQTAESVRAE 150
    TRNAYRAYEG LGCDVLAMVV NRVAREDREE LAARLDSLLA VPCYVLPDEP 200
    ALSAPTVAQI THALGGKVLL GDDSGLARDA LDFVFGGAML PNFLNALTPG 250
    CLVVTPGDRA DLVVGALAAH SAGTPPIAGV LLTLDERPSD EVLTLAARLA 300
    PGTPVVSVAG TSFPTAAELF SLEGKLNAAT PRKAETALGL FERYVDTGDL 350
    LKRVSAPSSD RLTPMMFEHK LLEQARSDKR RVVLPEGTET RVLHAAEVLL 400
    RRGVCDLTLL GPVDQIRKKA ADLGIDLGGS QLIDPVTSQL RDSFAEKYAQ 450
    LRAHKGVSVE LAYDVVADVN YFGTLMVQEG LADGMVSGSV HSTAATIRPA 500
    FEIIKTKPDT KIVSSVFFMC LADKVLVYGD CAVNPDPNAE QLCDIAVQSA 550
    ATARQFGVEP RIAMLSYSTG TSGSGADVDK VREATELVRL RRDDLKIEGP 600
    IQYDAAVEPS VAATKLPGSD VAGQASVLIF PDLNTGNNTY KAVQRSAGAI 650
    AVGPVMQGLR KPVNDLSRGA LVQDIVNTVA ITAIQAQSPH EKATAQ 696
    Length:696
    Mass (Da):74,275
    Last modified:June 1, 2003 - v1
    Checksum:i211801F5C781E0CD
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000030 Genomic DNA. Translation: BAC70534.1.
    RefSeqiNP_823999.1. NC_003155.4.

    Genome annotation databases

    EnsemblBacteriaiBAC70534; BAC70534; SAV_2823.
    GeneIDi1210558.
    KEGGisma:SAV_2823.
    PATRICi23719227. VBIStrAve112782_3023.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000030 Genomic DNA. Translation: BAC70534.1 .
    RefSeqi NP_823999.1. NC_003155.4.

    3D structure databases

    ProteinModelPortali Q82JD2.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 227882.SAV_2823.

    Proteomic databases

    PRIDEi Q82JD2.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAC70534 ; BAC70534 ; SAV_2823 .
    GeneIDi 1210558.
    KEGGi sma:SAV_2823.
    PATRICi 23719227. VBIStrAve112782_3023.

    Phylogenomic databases

    eggNOGi COG0280.
    HOGENOMi HOG000053797.
    KOi K13788.
    OMAi ATIRPAF.
    OrthoDBi EOG6BKJ5W.

    Enzyme and pathway databases

    UniPathwayi UPA00340 ; UER00459 .
    BioCyci SAVE227882:GJU1-2844-MONOMER.

    Family and domain databases

    Gene3Di 3.40.1390.20. 1 hit.
    3.40.50.300. 1 hit.
    InterProi IPR010766. DRTGG.
    IPR016475. P-Actrans_bac.
    IPR027417. P-loop_NTPase.
    IPR004614. P_AcTrfase.
    IPR002505. PTA_PTB.
    IPR028979. Ser_kin/Pase_Hpr_N_like.
    [Graphical view ]
    Pfami PF07085. DRTGG. 1 hit.
    PF01515. PTA_PTB. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF006107. PhpActrans_proteobac. 1 hit.
    SUPFAMi SSF52540. SSF52540. 1 hit.
    SSF75138. SSF75138. 1 hit.
    TIGRFAMsi TIGR00651. pta. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites."
      Omura S., Ikeda H., Ishikawa J., Hanamoto A., Takahashi C., Shinose M., Takahashi Y., Horikawa H., Nakazawa H., Osonoe T., Kikuchi H., Shiba T., Sakaki Y., Hattori M.
      Proc. Natl. Acad. Sci. U.S.A. 98:12215-12220(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 31267 / DSM 46492 / JCM 5070 / NCIMB 12804 / NRRL 8165 / MA-4680.
    2. "Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis."
      Ikeda H., Ishikawa J., Hanamoto A., Shinose M., Kikuchi H., Shiba T., Sakaki Y., Hattori M., Omura S.
      Nat. Biotechnol. 21:526-531(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 31267 / DSM 46492 / JCM 5070 / NCIMB 12804 / NRRL 8165 / MA-4680.

    Entry informationi

    Entry nameiPTA_STRAW
    AccessioniPrimary (citable) accession number: Q82JD2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 8, 2011
    Last sequence update: June 1, 2003
    Last modified: October 1, 2014
    This is version 66 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3