Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q82JD2 (PTA_STRAW) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphate acetyltransferase

EC=2.3.1.8
Alternative name(s):
Phosphotransacetylase
Gene names
Name:pta
Ordered Locus Names:SAV_2823
OrganismStreptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NCIMB 12804 / NRRL 8165 / MA-4680) [Complete proteome] [HAMAP]
Taxonomic identifier227882 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces

Protein attributes

Sequence length696 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in acetate metabolism By similarity.

Catalytic activity

Acetyl-CoA + phosphate = CoA + acetyl phosphate.

Pathway

Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 2/2.

Subcellular location

Cytoplasm Potential.

Domain

The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site By similarity.

Sequence similarities

In the N-terminal section; belongs to the CobB/CobQ family.

In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   Molecular functionAcyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processacetyl-CoA biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionphosphate acetyltransferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 696696Phosphate acetyltransferase
PRO_0000405552

Regions

Region367 – 696330Phosphate acetyltransferase

Sequences

Sequence LengthMass (Da)Tools
Q82JD2 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: 211801F5C781E0CD

FASTA69674,275
        10         20         30         40         50         60 
MTRSVYVTGI DRGDGRQVVE LGVMELLTRQ VDRVGVFRPL VHDGPDRLFE LLRARYRLAQ 

        70         80         90        100        110        120 
DPATVYGMDY HEASALQAEQ GTDELMSTLV DRFHLVARDY DVVLVLGTDF ADTQFPDELA 

       130        140        150        160        170        180 
LNARLANEFG AAVIPVVGGR GQTAESVRAE TRNAYRAYEG LGCDVLAMVV NRVAREDREE 

       190        200        210        220        230        240 
LAARLDSLLA VPCYVLPDEP ALSAPTVAQI THALGGKVLL GDDSGLARDA LDFVFGGAML 

       250        260        270        280        290        300 
PNFLNALTPG CLVVTPGDRA DLVVGALAAH SAGTPPIAGV LLTLDERPSD EVLTLAARLA 

       310        320        330        340        350        360 
PGTPVVSVAG TSFPTAAELF SLEGKLNAAT PRKAETALGL FERYVDTGDL LKRVSAPSSD 

       370        380        390        400        410        420 
RLTPMMFEHK LLEQARSDKR RVVLPEGTET RVLHAAEVLL RRGVCDLTLL GPVDQIRKKA 

       430        440        450        460        470        480 
ADLGIDLGGS QLIDPVTSQL RDSFAEKYAQ LRAHKGVSVE LAYDVVADVN YFGTLMVQEG 

       490        500        510        520        530        540 
LADGMVSGSV HSTAATIRPA FEIIKTKPDT KIVSSVFFMC LADKVLVYGD CAVNPDPNAE 

       550        560        570        580        590        600 
QLCDIAVQSA ATARQFGVEP RIAMLSYSTG TSGSGADVDK VREATELVRL RRDDLKIEGP 

       610        620        630        640        650        660 
IQYDAAVEPS VAATKLPGSD VAGQASVLIF PDLNTGNNTY KAVQRSAGAI AVGPVMQGLR 

       670        680        690 
KPVNDLSRGA LVQDIVNTVA ITAIQAQSPH EKATAQ 

« Hide

References

[1]"Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites."
Omura S., Ikeda H., Ishikawa J., Hanamoto A., Takahashi C., Shinose M., Takahashi Y., Horikawa H., Nakazawa H., Osonoe T., Kikuchi H., Shiba T., Sakaki Y., Hattori M.
Proc. Natl. Acad. Sci. U.S.A. 98:12215-12220(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 31267 / DSM 46492 / JCM 5070 / NCIMB 12804 / NRRL 8165 / MA-4680.
[2]"Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis."
Ikeda H., Ishikawa J., Hanamoto A., Shinose M., Kikuchi H., Shiba T., Sakaki Y., Hattori M., Omura S.
Nat. Biotechnol. 21:526-531(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 31267 / DSM 46492 / JCM 5070 / NCIMB 12804 / NRRL 8165 / MA-4680.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000030 Genomic DNA. Translation: BAC70534.1.
RefSeqNP_823999.1. NC_003155.4.

3D structure databases

ProteinModelPortalQ82JD2.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING227882.SAV_2823.

Proteomic databases

PRIDEQ82JD2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAC70534; BAC70534; SAV_2823.
GeneID1210558.
KEGGsma:SAV_2823.
PATRIC23719227. VBIStrAve112782_3023.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0280.
HOGENOMHOG000053797.
KOK13788.
OMAVTPLMFE.
OrthoDBEOG6BKJ5W.
ProtClustDBPRK05632.

Enzyme and pathway databases

BioCycSAVE227882:GJU1-2844-MONOMER.
UniPathwayUPA00340; UER00459.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
InterProIPR010766. DRTGG.
IPR016475. P-Actrans_bac.
IPR027417. P-loop_NTPase.
IPR004614. P_AcTrfase.
IPR002505. PTA_PTB.
[Graphical view]
PfamPF07085. DRTGG. 1 hit.
PF01515. PTA_PTB. 1 hit.
[Graphical view]
PIRSFPIRSF006107. PhpActrans_proteobac. 1 hit.
SUPFAMSSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR00651. pta. 1 hit.
ProtoNetSearch...

Entry information

Entry namePTA_STRAW
AccessionPrimary (citable) accession number: Q82JD2
Entry history
Integrated into UniProtKB/Swiss-Prot: March 8, 2011
Last sequence update: June 1, 2003
Last modified: April 16, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways