Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q82IE7

- EX7L_STRAW

UniProt

Q82IE7 - EX7L_STRAW

Protein

Exodeoxyribonuclease 7 large subunit

Gene

xseA

Organism
Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NCIMB 12804 / NRRL 8165 / MA-4680)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 79 (01 Oct 2014)
      Sequence version 1 (01 Jun 2003)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.UniRule annotation

    Catalytic activityi

    Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.UniRule annotation

    GO - Molecular functioni

    1. exodeoxyribonuclease VII activity Source: UniProtKB-HAMAP
    2. nucleic acid binding Source: InterPro

    Keywords - Molecular functioni

    Exonuclease, Hydrolase, Nuclease

    Enzyme and pathway databases

    BioCyciSAVE227882:GJU1-3235-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Exodeoxyribonuclease 7 large subunitUniRule annotation (EC:3.1.11.6UniRule annotation)
    Alternative name(s):
    Exodeoxyribonuclease VII large subunitUniRule annotation
    Short name:
    Exonuclease VII large subunitUniRule annotation
    Gene namesi
    Name:xseAUniRule annotation
    Ordered Locus Names:SAV_3211
    OrganismiStreptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NCIMB 12804 / NRRL 8165 / MA-4680)
    Taxonomic identifieri227882 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces
    ProteomesiUP000000428: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    2. exodeoxyribonuclease VII complex Source: InterPro

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 402402Exodeoxyribonuclease 7 large subunitPRO_0000303827Add
    BLAST

    Interactioni

    Subunit structurei

    Heterooligomer composed of large and small subunits.UniRule annotation

    Protein-protein interaction databases

    STRINGi227882.SAV_3211.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the XseA family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1570.
    HOGENOMiHOG000229264.
    KOiK03601.
    OMAiWIEGQIV.
    OrthoDBiEOG64R65J.

    Family and domain databases

    HAMAPiMF_00378. Exonuc_7_L.
    InterProiIPR003753. Exonuc_VII_L.
    IPR020579. Exonuc_VII_lsu_C.
    IPR004365. NA-bd_OB_tRNA.
    [Graphical view]
    PfamiPF02601. Exonuc_VII_L. 1 hit.
    PF01336. tRNA_anti-codon. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00237. xseA. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q82IE7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAANTSAETP LPVGEVSRLI GGWIDRLGAV WVEGQITQLS RRPGAGVVFM    50
    TLRDPSYDIS VGVTCYRQVF DAVADVVSEG ARVVVHAKPE WYAPRGQLSL 100
    RAAEIRPIGV GELLARLEQL KKSLAGEGLF VTERKKALPF LPQLIGLVCG 150
    RASAAERDVL ENARHRWPAV RFEVRNVAVQ GVHAVPQVVQ AVKELDARDD 200
    VDVIIVARGG GSVEDLLPFS DEQLVRAVAA CRTPVVSAIG HEPDTPLLDY 250
    VADLRASTPT DAAKKVVPDV GEEVERVRAL RDRARRCVRS VIEREERGLA 300
    HTLARPSIED PHRMVDERAD QVASLLDRGR RTLGHLLDRA DSELSHTHAR 350
    VVALSPAATL KRGYAVLQRA DGHAVRAPDE VTADEVLRAR VAEGEFTVRV 400
    DV 402
    Length:402
    Mass (Da):43,844
    Last modified:June 1, 2003 - v1
    Checksum:i863AB19C4C8F4A07
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000030 Genomic DNA. Translation: BAC70922.1.
    RefSeqiNP_824387.1. NC_003155.4.
    WP_010984641.1. NC_003155.4.

    Genome annotation databases

    EnsemblBacteriaiBAC70922; BAC70922; SAV_3211.
    GeneIDi1210689.
    KEGGisma:SAV_3211.
    PATRICi23720049. VBIStrAve112782_3431.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000030 Genomic DNA. Translation: BAC70922.1 .
    RefSeqi NP_824387.1. NC_003155.4.
    WP_010984641.1. NC_003155.4.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 227882.SAV_3211.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAC70922 ; BAC70922 ; SAV_3211 .
    GeneIDi 1210689.
    KEGGi sma:SAV_3211.
    PATRICi 23720049. VBIStrAve112782_3431.

    Phylogenomic databases

    eggNOGi COG1570.
    HOGENOMi HOG000229264.
    KOi K03601.
    OMAi WIEGQIV.
    OrthoDBi EOG64R65J.

    Enzyme and pathway databases

    BioCyci SAVE227882:GJU1-3235-MONOMER.

    Family and domain databases

    HAMAPi MF_00378. Exonuc_7_L.
    InterProi IPR003753. Exonuc_VII_L.
    IPR020579. Exonuc_VII_lsu_C.
    IPR004365. NA-bd_OB_tRNA.
    [Graphical view ]
    Pfami PF02601. Exonuc_VII_L. 1 hit.
    PF01336. tRNA_anti-codon. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00237. xseA. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites."
      Omura S., Ikeda H., Ishikawa J., Hanamoto A., Takahashi C., Shinose M., Takahashi Y., Horikawa H., Nakazawa H., Osonoe T., Kikuchi H., Shiba T., Sakaki Y., Hattori M.
      Proc. Natl. Acad. Sci. U.S.A. 98:12215-12220(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 31267 / DSM 46492 / JCM 5070 / NCIMB 12804 / NRRL 8165 / MA-4680.
    2. "Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis."
      Ikeda H., Ishikawa J., Hanamoto A., Shinose M., Kikuchi H., Shiba T., Sakaki Y., Hattori M., Omura S.
      Nat. Biotechnol. 21:526-531(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 31267 / DSM 46492 / JCM 5070 / NCIMB 12804 / NRRL 8165 / MA-4680.

    Entry informationi

    Entry nameiEX7L_STRAW
    AccessioniPrimary (citable) accession number: Q82IE7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 11, 2007
    Last sequence update: June 1, 2003
    Last modified: October 1, 2014
    This is version 79 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3