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Q82HE3 (CAPP_STRAW) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 70. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoenolpyruvate carboxylase

Short name=PEPC
Short name=PEPCase
EC=4.1.1.31
Gene names
Name:ppc
Ordered Locus Names:SAV_3566
OrganismStreptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NCIMB 12804 / NRRL 8165 / MA-4680) [Complete proteome] [HAMAP]
Taxonomic identifier227882 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces

Protein attributes

Sequence length910 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity. HAMAP-Rule MF_00595

Catalytic activity

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-. HAMAP-Rule MF_00595

Cofactor

Magnesium By similarity. HAMAP-Rule MF_00595

Sequence similarities

Belongs to the PEPCase type 1 family.

Ontologies

Keywords
   Biological processCarbon dioxide fixation
   LigandMagnesium
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processcarbon fixation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

oxaloacetate metabolic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

tricarboxylic acid cycle

Inferred from electronic annotation. Source: InterPro

   Molecular_functionmagnesium ion binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

phosphoenolpyruvate carboxylase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 910910Phosphoenolpyruvate carboxylase HAMAP-Rule MF_00595
PRO_0000166627

Sites

Active site1361 By similarity
Active site5681 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q82HE3 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: D327E1B9D164403D

FASTA910101,200
        10         20         30         40         50         60 
MSSADDQTTT TSSELRADIR RLGDLLGETL VRQEGPELLD LVEKVRRLTR EDGEAAAELL 

        70         80         90        100        110        120 
RGTELETAAK LVRAFSTYFH LANVTEQVHR GRELRTKRAA EGGLLARTAD RLKDADPEHL 

       130        140        150        160        170        180 
RATVKNLNVR PVFTAHPTEA ARRSVLNKLR RIAALLETPV IEADRRRYDT RLAENIDLVW 

       190        200        210        220        230        240 
QTDELRVVRP EPADEARNAI YYLDELHAGA VGDVLEDLTA ELERVGVQLP DDTRPLTFGT 

       250        260        270        280        290        300 
WIGGDRDGNP NVTPEVTWDV LILQHEHGIN DALELIDELR GFLSNSIRYT GATEELLTSL 

       310        320        330        340        350        360 
GTDLERLPEI SPRYKRLNAE EPYRLKATCI RQKLENTKQR LAKGTAHQPG RDYLGTGELL 

       370        380        390        400        410        420 
HDLKLIQTSL REHRGGLFAD GRMDRTIRTL AAFGLQLATM DVREHADAHH YALGQLFDRL 

       430        440        450        460        470        480 
GEESWRYADM PRDYRGKLLA KELRSRRPLA PSPAPLDAAG AKTLGVFHTV KRALAVFGPE 

       490        500        510        520        530        540 
VIESYIISMC QGADDVFAAA VLAREAGLLD LHAGWAKIGI VPLLETTDEL KAADTILEDM 

       550        560        570        580        590        600 
LSDPSYRRLV ALRGDVQEVM LGYSDSSKFG GITTSQWEIH RAQRRLRDVA HRYGVRLRLF 

       610        620        630        640        650        660 
HGRGGTVGRG GGPSHDAILA QPWGTLEGEI KVTEQGEVIS DKYLVPSLAR ENLELTVAAT 

       670        680        690        700        710        720 
LQASALHTAP RQSDEALARW DAAMDVVSDA AHSAYRRLVE DPDLPTYFLA STPVDQLADL 

       730        740        750        760        770        780 
HLGSRPSRRP GSGVSLDGLR AIPWVFGWTQ SRQIVPGWFG VGSGLKALRE AGLDTVLDEM 

       790        800        810        820        830        840 
HEQWHFFRNF LSNVEMTLAK TDLRIARHYV DTLVPDHLKH VFATIEAEHE LTVREVLRIT 

       850        860        870        880        890        900 
GGEKLLDTHP VLQQTFAIRD AYLDPISYLQ VALLKRQRDA AAADTPPDPL LARALLLTVN 

       910 
GVAAGLRNTG 

« Hide

References

[1]"Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites."
Omura S., Ikeda H., Ishikawa J., Hanamoto A., Takahashi C., Shinose M., Takahashi Y., Horikawa H., Nakazawa H., Osonoe T., Kikuchi H., Shiba T., Sakaki Y., Hattori M.
Proc. Natl. Acad. Sci. U.S.A. 98:12215-12220(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 31267 / DSM 46492 / JCM 5070 / NCIMB 12804 / NRRL 8165 / MA-4680.
[2]"Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis."
Ikeda H., Ishikawa J., Hanamoto A., Shinose M., Kikuchi H., Shiba T., Sakaki Y., Hattori M., Omura S.
Nat. Biotechnol. 21:526-531(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 31267 / DSM 46492 / JCM 5070 / NCIMB 12804 / NRRL 8165 / MA-4680.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000030 Genomic DNA. Translation: BAC71278.1.
RefSeqNP_824743.1. NC_003155.4.

3D structure databases

ProteinModelPortalQ82HE3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING227882.SAV_3566.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAC71278; BAC71278; SAV_3566.
GeneID1210769.
KEGGsma:SAV_3566.
PATRIC23720817. VBIStrAve112782_3813.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2352.
HOGENOMHOG000238647.
KOK01595.
OMAFADGRMD.
OrthoDBEOG6TJ7T8.

Enzyme and pathway databases

BioCycSAVE227882:GJU1-3593-MONOMER.

Family and domain databases

HAMAPMF_00595. PEPcase_type1.
InterProIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSPR00150. PEPCARBXLASE.
SUPFAMSSF51621. SSF51621. 1 hit.
PROSITEPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCAPP_STRAW
AccessionPrimary (citable) accession number: Q82HE3
Entry history
Integrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: June 1, 2003
Last modified: May 14, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families