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Protein

DNA replication and repair protein RecF

Gene

recF

Organism
Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi30 – 37ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processDNA damage, DNA repair, DNA replication, SOS response
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciSAVE227882:G1G23-4544-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
DNA replication and repair protein RecFUniRule annotation
Gene namesi
Name:recFUniRule annotation
Ordered Locus Names:SAV_4319
OrganismiStreptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)
Taxonomic identifieri227882 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomyces
Proteomesi

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001964691 – 373DNA replication and repair protein RecFAdd BLAST373

Interactioni

Protein-protein interaction databases

STRINGi227882.SAV_4319

Structurei

3D structure databases

ProteinModelPortaliQ82FD5
SMRiQ82FD5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RecF family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C3X Bacteria
COG1195 LUCA
HOGENOMiHOG000269561
KOiK03629
OMAiGQQKSFL
OrthoDBiPOG091H00U7

Family and domain databases

HAMAPiMF_00365 RecF, 1 hit
InterProiView protein in InterPro
IPR001238 DNA-binding_RecF
IPR018078 DNA-binding_RecF_CS
IPR027417 P-loop_NTPase
IPR003395 RecF/RecN/SMC_N
PANTHERiPTHR32182:SF0 PTHR32182:SF0, 1 hit
PfamiView protein in Pfam
PF02463 SMC_N, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00611 recf, 1 hit
PROSITEiView protein in PROSITE
PS00617 RECF_1, 1 hit
PS00618 RECF_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q82FD5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHVTHLSLAD FRSYARVEVP LDPGVTAFVG PNGQGKTNLV EAVGYLATLG
60 70 80 90 100
SHRVSSDAPL VRMGAERAII RAQVRQDERR QLVELELNPG KANRARINRS
110 120 130 140 150
SQVRPRDVLG IVRTVLFAPE DLALIKGDPG ERRRFLDELI TARSPRMAGV
160 170 180 190 200
RSDYERVLKQ RNTLLKTAAL ARRHGGRSMD LSTLDVWDQH LARAGAELLA
210 220 230 240 250
QRLDLIAALQ PLADKAYEQL APGGGPIALE YKPSAPGEAH TRDALYEQLM
260 270 280 290 300
AALAEARKQE IERGVTLVGP QRDELLLKLG QLPAKGYASH GESWSYALAL
310 320 330 340 350
RLASYDLLRA EGNEPVLVLD DVFAELDTRR RERLAELVAP GEQVLVTAAV
360 370
DDDVPGVLAG TRYTVSEGTV ERV
Length:373
Mass (Da):40,900
Last modified:June 1, 2003 - v1
Checksum:iE0D008A00322A05F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000030 Genomic DNA Translation: BAC72031.1
RefSeqiWP_010985744.1, NZ_JZJK01000079.1

Genome annotation databases

EnsemblBacteriaiBAC72031; BAC72031; SAVERM_4319
KEGGisma:SAVERM_4319

Entry informationi

Entry nameiRECF_STRAW
AccessioniPrimary (citable) accession number: Q82FD5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 16, 2004
Last sequence update: June 1, 2003
Last modified: May 23, 2018
This is version 89 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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