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Protein
Submitted name:

Putative dihydrolipoamide acyltransferase component

Gene

bkdH

Organism
Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NCIMB 12804 / NRRL 8165 / MA-4680)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. transferase activity, transferring acyl groups Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

AcyltransferaseUniRule annotationImported, Transferase

Enzyme and pathway databases

BioCyciSAVE227882:GJU1-4429-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Putative dihydrolipoamide acyltransferase componentImported
Gene namesi
Name:bkdHImported
Ordered Locus Names:SAV_4378Imported
OrganismiStreptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NCIMB 12804 / NRRL 8165 / MA-4680)Imported
Taxonomic identifieri227882 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces
ProteomesiUP000000428: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi227882.SAV_4378.

Structurei

3D structure databases

ProteinModelPortaliQ82F85.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the 2-oxoacid dehydrogenase family.UniRule annotation
Contains 1 lipoyl-binding domain.UniRule annotation

Keywords - Domaini

LipoylUniRule annotationSAAS annotation

Phylogenomic databases

HOGENOMiHOG000281564.
KOiK00627.
OMAiYKHYVNL.
OrthoDBiEOG610413.

Family and domain databases

Gene3Di3.30.559.10. 1 hit.
4.10.320.10. 1 hit.
InterProiIPR003016. 2-oxoA_DH_lipoyl-BS.
IPR001078. 2-oxoacid_DH_actylTfrase.
IPR000089. Biotin_lipoyl.
IPR023213. CAT-like_dom.
IPR004167. E3-bd.
IPR011053. Single_hybrid_motif.
[Graphical view]
PfamiPF00198. 2-oxoacid_dh. 1 hit.
PF00364. Biotin_lipoyl. 1 hit.
PF02817. E3_binding. 1 hit.
[Graphical view]
SUPFAMiSSF47005. SSF47005. 1 hit.
SSF51230. SSF51230. 1 hit.
PROSITEiPS50968. BIOTINYL_LIPOYL. 1 hit.
PS00189. LIPOYL. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q82F85-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTEASVREFK MPDVGEGLTE AEILKWYVQP GDTVTDGQVV CEVETAKAAV
60 70 80 90 100
ELPIPYDGVV RELRFPEGTT VDVGQVIIAV DVAGDAPVAE IPVPAQEAPV
110 120 130 140 150
QEEPKPEGRK PVLVGYGVAE SSTKRRPRKS APASEPAAEG TYFAATVLQG
160 170 180 190 200
IQGELNGHGA VKQRPLAKPP VRKLAKDLGV DLATITPSGP DGVITREDVH
210 220 230 240 250
AAVAPPPPAP QPVQTPAAPA PAPVAAYDTA RETRVPVKGV RKATAAAMVG
260 270 280 290 300
SAFTAPHVTE FVTVDVTRTM KLVEELKQDK EFTGLRVNPL LLIAKALLVA
310 320 330 340 350
IKRNPDINAS WDEANQEIVL KHYVNLGIAA ATPRGLIVPN IKDAHAKTLP
360 370 380 390 400
QLAESLGELV STAREGKTSP TAMQGGTVTI TNVGVFGVDT GTPILNPGES
410 420 430 440 450
AILAVGAIKL QPWVHKGKVK PRQVTTLALS FDHRLVDGEL GSKVLADVAA
460
ILEQPKRLIT WA
Length:462
Mass (Da):48,745
Last modified:June 1, 2003 - v1
Checksum:i93BDAE3F63146818
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000030 Genomic DNA. Translation: BAC72090.1.
RefSeqiNP_825555.1. NC_003155.4.
WP_010985803.1. NC_003155.4.

Genome annotation databases

EnsemblBacteriaiBAC72090; BAC72090; SAV_4378.
GeneIDi1210981.
KEGGisma:SAV_4378.
PATRICi23722559. VBIStrAve112782_4661.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000030 Genomic DNA. Translation: BAC72090.1.
RefSeqiNP_825555.1. NC_003155.4.
WP_010985803.1. NC_003155.4.

3D structure databases

ProteinModelPortaliQ82F85.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi227882.SAV_4378.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAC72090; BAC72090; SAV_4378.
GeneIDi1210981.
KEGGisma:SAV_4378.
PATRICi23722559. VBIStrAve112782_4661.

Phylogenomic databases

HOGENOMiHOG000281564.
KOiK00627.
OMAiYKHYVNL.
OrthoDBiEOG610413.

Enzyme and pathway databases

BioCyciSAVE227882:GJU1-4429-MONOMER.

Family and domain databases

Gene3Di3.30.559.10. 1 hit.
4.10.320.10. 1 hit.
InterProiIPR003016. 2-oxoA_DH_lipoyl-BS.
IPR001078. 2-oxoacid_DH_actylTfrase.
IPR000089. Biotin_lipoyl.
IPR023213. CAT-like_dom.
IPR004167. E3-bd.
IPR011053. Single_hybrid_motif.
[Graphical view]
PfamiPF00198. 2-oxoacid_dh. 1 hit.
PF00364. Biotin_lipoyl. 1 hit.
PF02817. E3_binding. 1 hit.
[Graphical view]
SUPFAMiSSF47005. SSF47005. 1 hit.
SSF51230. SSF51230. 1 hit.
PROSITEiPS50968. BIOTINYL_LIPOYL. 1 hit.
PS00189. LIPOYL. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites."
    Omura S., Ikeda H., Ishikawa J., Hanamoto A., Takahashi C., Shinose M., Takahashi Y., Horikawa H., Nakazawa H., Osonoe T., Kikuchi H., Shiba T., Sakaki Y., Hattori M.
    Proc. Natl. Acad. Sci. U.S.A. 98:12215-12220(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 31267 / DSM 46492 / JCM 5070 / NCIMB 12804 / NRRL 8165 / MA-4680Imported.
  2. "Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis."
    Ikeda H., Ishikawa J., Hanamoto A., Shinose M., Kikuchi H., Shiba T., Sakaki Y., Hattori M., Omura S.
    Nat. Biotechnol. 21:526-531(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiQ82F85_STRAW
AccessioniPrimary (citable) accession number: Q82F85
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: February 4, 2015
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.