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Protein

Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex

Gene

bkdH

Organism
Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cofactori

(R)-lipoateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAcyltransferaseUniRule annotationImported, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complexUniRule annotation (EC:2.3.1.-UniRule annotation)
Gene namesi
Name:bkdHImported
ORF Names:SAVERM_4378Imported
OrganismiStreptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)Imported
Taxonomic identifieri227882 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomyces
Proteomesi
  • UP000000428 Componenti: Chromosome

PTM / Processingi

Proteomic databases

PRIDEiQ82F85

Interactioni

Protein-protein interaction databases

STRINGi227882.SAV_4378

Structurei

3D structure databases

ProteinModelPortaliQ82F85
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 81Lipoyl-bindingInterPro annotationAdd BLAST76
Domaini166 – 203Peripheral subunit-binding (PSBD)InterPro annotationAdd BLAST38

Sequence similaritiesi

Belongs to the 2-oxoacid dehydrogenase family.UniRule annotation

Keywords - Domaini

LipoylUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4107RN0 Bacteria
COG0508 LUCA
HOGENOMiHOG000281564
KOiK00627
OMAiTMEFESF
OrthoDBiPOG091H05OF

Family and domain databases

Gene3Di3.30.559.10, 1 hit
4.10.320.10, 1 hit
InterProiView protein in InterPro
IPR003016 2-oxoA_DH_lipoyl-BS
IPR001078 2-oxoacid_DH_actylTfrase
IPR000089 Biotin_lipoyl
IPR023213 CAT-like_dom_sf
IPR036625 E3-bd_dom_sf
IPR004167 PSBD
IPR011053 Single_hybrid_motif
PfamiView protein in Pfam
PF00198 2-oxoacid_dh, 1 hit
PF00364 Biotin_lipoyl, 1 hit
PF02817 E3_binding, 1 hit
SUPFAMiSSF47005 SSF47005, 1 hit
SSF51230 SSF51230, 1 hit
PROSITEiView protein in PROSITE
PS50968 BIOTINYL_LIPOYL, 1 hit
PS00189 LIPOYL, 1 hit
PS51826 PSBD, 1 hit

Sequencei

Sequence statusi: Complete.

Q82F85-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTEASVREFK MPDVGEGLTE AEILKWYVQP GDTVTDGQVV CEVETAKAAV
60 70 80 90 100
ELPIPYDGVV RELRFPEGTT VDVGQVIIAV DVAGDAPVAE IPVPAQEAPV
110 120 130 140 150
QEEPKPEGRK PVLVGYGVAE SSTKRRPRKS APASEPAAEG TYFAATVLQG
160 170 180 190 200
IQGELNGHGA VKQRPLAKPP VRKLAKDLGV DLATITPSGP DGVITREDVH
210 220 230 240 250
AAVAPPPPAP QPVQTPAAPA PAPVAAYDTA RETRVPVKGV RKATAAAMVG
260 270 280 290 300
SAFTAPHVTE FVTVDVTRTM KLVEELKQDK EFTGLRVNPL LLIAKALLVA
310 320 330 340 350
IKRNPDINAS WDEANQEIVL KHYVNLGIAA ATPRGLIVPN IKDAHAKTLP
360 370 380 390 400
QLAESLGELV STAREGKTSP TAMQGGTVTI TNVGVFGVDT GTPILNPGES
410 420 430 440 450
AILAVGAIKL QPWVHKGKVK PRQVTTLALS FDHRLVDGEL GSKVLADVAA
460
ILEQPKRLIT WA
Length:462
Mass (Da):48,745
Last modified:June 1, 2003 - v1
Checksum:i93BDAE3F63146818
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000030 Genomic DNA Translation: BAC72090.1

Genome annotation databases

EnsemblBacteriaiBAC72090; BAC72090; SAVERM_4378
KEGGisma:SAVERM_4378

Similar proteinsi

Entry informationi

Entry nameiQ82F85_STRAW
AccessioniPrimary (citable) accession number: Q82F85
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: March 28, 2018
This is version 107 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health