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Protein

Glutamate decarboxylase

Gene

gadB2

Organism
Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDecarboxylaseUniRule annotation, Lyase
LigandPyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciSAVE227882:G1G23-4900-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
Name:gadB2Imported
ORF Names:SAVERM_4655Imported
OrganismiStreptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)Imported
Taxonomic identifieri227882 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomyces
Proteomesi
  • UP000000428 Componenti: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei283N6-(pyridoxal phosphate)lysineUniRule annotation1

Interactioni

Protein-protein interaction databases

STRINGi227882.SAV_4655

Structurei

3D structure databases

ProteinModelPortaliQ82EG0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CVK Bacteria
COG0076 LUCA
HOGENOMiHOG000070228
KOiK01580
OMAiRPNLVMG
OrthoDBiPOG091H06F5

Family and domain databases

Gene3Di3.40.640.10, 1 hit
InterProiView protein in InterPro
IPR010107 Glutamate_decarboxylase
IPR002129 PyrdxlP-dep_de-COase
IPR015424 PyrdxlP-dep_Trfase
IPR015421 PyrdxlP-dep_Trfase_major
PANTHERiPTHR43321 PTHR43321, 1 hit
PfamiView protein in Pfam
PF00282 Pyridoxal_deC, 1 hit
SUPFAMiSSF53383 SSF53383, 1 hit
TIGRFAMsiTIGR01788 Glu-decarb-GAD, 1 hit

Sequencei

Sequence statusi: Complete.

Q82EG0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPLHKGPVKS DERPMSFNPF FGEANPVSGM TEAPPKHRLA DGPLPPSTAY
60 70 80 90 100
QLVHDELMLD GNARLNLATF VTTWMEPQAG VLMAECQDKN MIDKDEYPRT
110 120 130 140 150
AELEKRCVAM LADLWNAPDA GAAVGCSTTG SSEACMLAGL ALKRRWARRN
160 170 180 190 200
ADRYPARDVR PNLVMGINVQ VCWEKFCNFW EVEMRQVPLE GERYHLDPGA
210 220 230 240 250
AAELCDENTI GVVGILGSTF DGSYEPIAEL CAALDALQER TGLDIPVHVD
260 270 280 290 300
GASGAMIAPF LDEDLVWDFR LPRVASINTS GHKYGLVSPG VGWALWRDSE
310 320 330 340 350
ALPEELVFRV NYLGGNMPTF ALNFSRPGAQ VVAQYYTFLR LGREGFRAVQ
360 370 380 390 400
QTTRNVARSL AERVAALGDF HLLTRGDELP VFAFTTAPEV ASYDVFDVSR
410 420 430 440 450
RMREHGWLVP AYTFPPNRED LSVLRVVCRN GFSTDLAELF VEDLSRLLPD
460 470
LRRQARPQTH DKDAATGFHH
Length:470
Mass (Da):52,225
Last modified:June 1, 2003 - v1
Checksum:iD77705B0991C0B1F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000030 Genomic DNA Translation: BAC72367.1
RefSeqiWP_010986079.1, NZ_JZJK01000062.1

Genome annotation databases

EnsemblBacteriaiBAC72367; BAC72367; SAVERM_4655
KEGGisma:SAVERM_4655

Similar proteinsi

Entry informationi

Entry nameiQ82EG0_STRAW
AccessioniPrimary (citable) accession number: Q82EG0
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: April 25, 2018
This is version 99 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health