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Protein

Probable cytochrome c oxidase polypeptide 4

Gene

ctaF

Organism
Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Part of cytochrome c oxidase, its function is unknown.By similarity

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Enzyme and pathway databases

BioCyciSAVE227882:GJU1-6129-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable cytochrome c oxidase polypeptide 4 (EC:1.9.3.1)
Alternative name(s):
Cytochrome aa3 subunit 4
Cytochrome c oxidase polypeptide IV
Gene namesi
Name:ctaF
Ordered Locus Names:SAV_6049
OrganismiStreptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)
Taxonomic identifieri227882 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomyces
Proteomesi
  • UP000000428 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei5 – 2521HelicalSequence analysisAdd
BLAST
Transmembranei33 – 5321HelicalSequence analysisAdd
BLAST
Transmembranei86 – 10621HelicalSequence analysisAdd
BLAST
Transmembranei107 – 12721HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 132132Probable cytochrome c oxidase polypeptide 4PRO_0000220021Add
BLAST

Interactioni

Subunit structurei

Associates with subunits I, II and III to form cytochrome c oxidase.By similarity

Protein-protein interaction databases

STRINGi227882.SAV_6049.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105MCD. Bacteria.
ENOG4111V6C. LUCA.
HOGENOMiHOG000237887.
OMAiGTYFRFV.
OrthoDBiPOG091H0B59.

Family and domain databases

InterProiIPR021050. Cyt_c_oxidase_su4_actinobac.
[Graphical view]
PfamiPF12270. Cyt_c_ox_IV. 1 hit.
[Graphical view]
PIRSFiPIRSF017385. CtaF. 1 hit.

Sequencei

Sequence statusi: Complete.

Q82AK8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKIQGKMFIW LAVFILAMAI IYGVWSKEPA GTTALFLAFG LSIMIGYYLA
60 70 80 90 100
FTARRVDAGA QDNKEADVAD DAGEVGFFSP HSWQPLALGI GGALAFMGVV
110 120 130
FGWWLLYFSA PIILIGLWGW VFEYYRGESR TQ
Length:132
Mass (Da):14,643
Last modified:June 1, 2003 - v1
Checksum:i23758A003AEA6E29
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000030 Genomic DNA. Translation: BAC73760.1.
RefSeqiWP_010987450.1. NZ_JZJK01000089.1.

Genome annotation databases

EnsemblBacteriaiBAC73760; BAC73760; SAV_6049.
KEGGisma:SAV_6049.
PATRICi23726124. VBIStrAve112782_6415.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000030 Genomic DNA. Translation: BAC73760.1.
RefSeqiWP_010987450.1. NZ_JZJK01000089.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi227882.SAV_6049.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAC73760; BAC73760; SAV_6049.
KEGGisma:SAV_6049.
PATRICi23726124. VBIStrAve112782_6415.

Phylogenomic databases

eggNOGiENOG4105MCD. Bacteria.
ENOG4111V6C. LUCA.
HOGENOMiHOG000237887.
OMAiGTYFRFV.
OrthoDBiPOG091H0B59.

Enzyme and pathway databases

BioCyciSAVE227882:GJU1-6129-MONOMER.

Family and domain databases

InterProiIPR021050. Cyt_c_oxidase_su4_actinobac.
[Graphical view]
PfamiPF12270. Cyt_c_ox_IV. 1 hit.
[Graphical view]
PIRSFiPIRSF017385. CtaF. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiCOX4_STRAW
AccessioniPrimary (citable) accession number: Q82AK8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: June 1, 2003
Last modified: September 7, 2016
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.