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Q82AK8

- COX4_STRAW

UniProt

Q82AK8 - COX4_STRAW

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Protein
Probable cytochrome c oxidase polypeptide 4
Gene
ctaF, SAV_6049
Organism
Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NCIMB 12804 / NRRL 8165 / MA-4680)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Part of cytochrome c oxidase, its function is unknown By similarity.

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

GO - Molecular functioni

  1. cytochrome-c oxidase activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Molecular functioni

    Oxidoreductase

    Enzyme and pathway databases

    BioCyciSAVE227882:GJU1-6129-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable cytochrome c oxidase polypeptide 4 (EC:1.9.3.1)
    Alternative name(s):
    Cytochrome aa3 subunit 4
    Cytochrome c oxidase polypeptide IV
    Gene namesi
    Name:ctaF
    Ordered Locus Names:SAV_6049
    OrganismiStreptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NCIMB 12804 / NRRL 8165 / MA-4680)
    Taxonomic identifieri227882 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces
    ProteomesiUP000000428: Chromosome

    Subcellular locationi

    Topology

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei5 – 2521Helical; Reviewed prediction
    Add
    BLAST
    Transmembranei33 – 5321Helical; Reviewed prediction
    Add
    BLAST
    Transmembranei86 – 10621Helical; Reviewed prediction
    Add
    BLAST
    Transmembranei107 – 12721Helical; Reviewed prediction
    Add
    BLAST

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell
    Complete GO annotation...

    Keywords - Cellular componenti

    Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 132132Probable cytochrome c oxidase polypeptide 4
    PRO_0000220021Add
    BLAST

    Interactioni

    Subunit structurei

    Associates with subunits I, II and III to form cytochrome c oxidase By similarity.

    Protein-protein interaction databases

    STRINGi227882.SAV_6049.

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG07397.
    HOGENOMiHOG000237887.
    OMAiGTYFRFV.
    OrthoDBiEOG63FW2X.

    Family and domain databases

    InterProiIPR021050. Cyt_c_oxidase_su4_actinobac.
    [Graphical view]
    PfamiPF12270. Cyt_c_ox_IV. 1 hit.
    [Graphical view]
    PIRSFiPIRSF017385. CtaF. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q82AK8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKIQGKMFIW LAVFILAMAI IYGVWSKEPA GTTALFLAFG LSIMIGYYLA    50
    FTARRVDAGA QDNKEADVAD DAGEVGFFSP HSWQPLALGI GGALAFMGVV 100
    FGWWLLYFSA PIILIGLWGW VFEYYRGESR TQ 132
    Length:132
    Mass (Da):14,643
    Last modified:June 1, 2003 - v1
    Checksum:i23758A003AEA6E29
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000030 Genomic DNA. Translation: BAC73760.1.
    RefSeqiNP_827225.1. NC_003155.4.

    Genome annotation databases

    EnsemblBacteriaiBAC73760; BAC73760; SAV_6049.
    GeneIDi1216508.
    KEGGisma:SAV_6049.
    PATRICi23726124. VBIStrAve112782_6415.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000030 Genomic DNA. Translation: BAC73760.1 .
    RefSeqi NP_827225.1. NC_003155.4.

    3D structure databases

    ModBasei Search...

    Protein-protein interaction databases

    STRINGi 227882.SAV_6049.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAC73760 ; BAC73760 ; SAV_6049 .
    GeneIDi 1216508.
    KEGGi sma:SAV_6049.
    PATRICi 23726124. VBIStrAve112782_6415.

    Phylogenomic databases

    eggNOGi NOG07397.
    HOGENOMi HOG000237887.
    OMAi GTYFRFV.
    OrthoDBi EOG63FW2X.

    Enzyme and pathway databases

    BioCyci SAVE227882:GJU1-6129-MONOMER.

    Family and domain databases

    InterProi IPR021050. Cyt_c_oxidase_su4_actinobac.
    [Graphical view ]
    Pfami PF12270. Cyt_c_ox_IV. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF017385. CtaF. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites."
      Omura S., Ikeda H., Ishikawa J., Hanamoto A., Takahashi C., Shinose M., Takahashi Y., Horikawa H., Nakazawa H., Osonoe T., Kikuchi H., Shiba T., Sakaki Y., Hattori M.
      Proc. Natl. Acad. Sci. U.S.A. 98:12215-12220(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 31267 / DSM 46492 / JCM 5070 / NCIMB 12804 / NRRL 8165 / MA-4680.
    2. "Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis."
      Ikeda H., Ishikawa J., Hanamoto A., Shinose M., Kikuchi H., Shiba T., Sakaki Y., Hattori M., Omura S.
      Nat. Biotechnol. 21:526-531(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 31267 / DSM 46492 / JCM 5070 / NCIMB 12804 / NRRL 8165 / MA-4680.

    Entry informationi

    Entry nameiCOX4_STRAW
    AccessioniPrimary (citable) accession number: Q82AK8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 26, 2005
    Last sequence update: June 1, 2003
    Last modified: May 14, 2014
    This is version 68 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3

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