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Q829V7 (G6PI2_STRAW) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase 2

Short name=GPI 2
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase 2
Short name=PGI 2
Phosphohexose isomerase 2
Short name=PHI 2
Gene names
Name:pgi2
Ordered Locus Names:SAV_6302
OrganismStreptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NCIMB 12804 / NRRL 8165 / MA-4680) [Complete proteome] [HAMAP]
Taxonomic identifier227882 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces

Protein attributes

Sequence length550 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 550550Glucose-6-phosphate isomerase 2 HAMAP-Rule MF_00473
PRO_0000180748

Sites

Active site3591Proton donor By similarity
Active site3901 By similarity
Active site5141 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q829V7 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: 3AFA3A5540572DAF

FASTA55060,636
        10         20         30         40         50         60 
MNADSRTRLN QRPEWTALAK HREELAGTHL RDLFAADPGR GAGYTLEVGD LHVDYSKHLV 

        70         80         90        100        110        120 
TDETLRLLRE LAAATDVFGL RDAMFRGEKI NVTEDRAVLH TALRAPRDAV VEVDGENVVP 

       130        140        150        160        170        180 
AVHAVLDKMS TFAERVRTGE WTGHTGKPIK NIVNVGIGGS DLGPAMAYEV LRSFTDRSLT 

       190        200        210        220        230        240 
VRFVSNVDGA DLHEAVRDLD PAETLFVIAS KTFTTIETIT NATSARDWLL TELKAGQEAV 

       250        260        270        280        290        300 
AKHFVALSTN AEKVSEFGID TANMFEFWDW VGGRYSFDSA IGLSLMIAIG PERFREMLDG 

       310        320        330        340        350        360 
FRIVDEHFES APAEDNVPLL LGLLGIWYGN FHDAQSHAVL PYSHYLSKFT AYLQQLDMES 

       370        380        390        400        410        420 
NGKSVQRDGN PVEWETGPVV WGTPGTNGQH AYYQLIHQGT KLIPADFIGF AEPVADLLPG 

       430        440        450        460        470        480 
LVAQHDLLMA NFFAQTQALA FGKTPDEVRA EGVPEQLVPH KTFKGNHPTT TILAKELTPS 

       490        500        510        520        530        540 
VLGQLIALYE HKVFVQGAVW NIDSFDQWGV ELGKVLAKRV EPALTEGADV PGLDESTKAL 

       550 
VAKYRQLRGR 

« Hide

References

[1]"Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites."
Omura S., Ikeda H., Ishikawa J., Hanamoto A., Takahashi C., Shinose M., Takahashi Y., Horikawa H., Nakazawa H., Osonoe T., Kikuchi H., Shiba T., Sakaki Y., Hattori M.
Proc. Natl. Acad. Sci. U.S.A. 98:12215-12220(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 31267 / DSM 46492 / JCM 5070 / NCIMB 12804 / NRRL 8165 / MA-4680.
[2]"Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis."
Ikeda H., Ishikawa J., Hanamoto A., Shinose M., Kikuchi H., Shiba T., Sakaki Y., Hattori M., Omura S.
Nat. Biotechnol. 21:526-531(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 31267 / DSM 46492 / JCM 5070 / NCIMB 12804 / NRRL 8165 / MA-4680.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000030 Genomic DNA. Translation: BAC74013.1.
RefSeqNP_827478.1. NC_003155.4.

3D structure databases

ProteinModelPortalQ829V7.
SMRQ829V7. Positions 2-548.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING227882.SAV_6302.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAC74013; BAC74013; SAV_6302.
GeneID1211455.
KEGGsma:SAV_6302.
PATRIC23726660. VBIStrAve112782_6682.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000261371.
KOK01810.
OMAPICVDGT.
OrthoDBEOG64R61J.

Enzyme and pathway databases

BioCycSAVE227882:GJU1-6383-MONOMER.
UniPathwayUPA00109; UER00181.

Family and domain databases

Gene3D1.10.1390.10. 1 hit.
HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI2_STRAW
AccessionPrimary (citable) accession number: Q829V7
Entry history
Integrated into UniProtKB/Swiss-Prot: March 29, 2005
Last sequence update: June 1, 2003
Last modified: June 11, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways