ID   Q828C5_STRAW            Unreviewed;       384 AA.
AC   Q828C5;
DT   01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2003, sequence version 1.
DT   27-MAR-2024, entry version 96.
DE   SubName: Full=Magnesium or manganese-dependent protein phosphatase {ECO:0000313|EMBL:BAC74455.1};
GN   Name=prpB12 {ECO:0000313|EMBL:BAC74455.1};
GN   ORFNames=SAVERM_6744 {ECO:0000313|EMBL:BAC74455.1};
OS   Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC
OS   14893 / NCIMB 12804 / NRRL 8165 / MA-4680).
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=227882 {ECO:0000313|EMBL:BAC74455.1, ECO:0000313|Proteomes:UP000000428};
RN   [1] {ECO:0000313|EMBL:BAC74455.1, ECO:0000313|Proteomes:UP000000428}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 /
RC   NRRL 8165 / MA-4680 {ECO:0000313|Proteomes:UP000000428};
RX   PubMed=11572948; DOI=10.1073/pnas.211433198;
RA   Omura S., Ikeda H., Ishikawa J., Hanamoto A., Takahashi C., Shinose M.,
RA   Takahashi Y., Horikawa H., Nakazawa H., Osonoe T., Kikuchi H., Shiba T.,
RA   Sakaki Y., Hattori M.;
RT   "Genome sequence of an industrial microorganism Streptomyces avermitilis:
RT   deducing the ability of producing secondary metabolites.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:12215-12220(2001).
RN   [2] {ECO:0000313|EMBL:BAC74455.1, ECO:0000313|Proteomes:UP000000428}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 /
RC   NRRL 8165 / MA-4680 {ECO:0000313|Proteomes:UP000000428};
RX   PubMed=12692562; DOI=10.1038/nbt820;
RA   Ikeda H., Ishikawa J., Hanamoto A., Shinose M., Kikuchi H., Shiba T.,
RA   Sakaki Y., Hattori M., Omura S.;
RT   "Complete genome sequence and comparative analysis of the industrial
RT   microorganism Streptomyces avermitilis.";
RL   Nat. Biotechnol. 21:526-531(2003).
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DR   EMBL; BA000030; BAC74455.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q828C5; -.
DR   KEGG; sma:SAVERM_6744; -.
DR   eggNOG; COG2208; Bacteria.
DR   HOGENOM; CLU_045535_0_0_11; -.
DR   OrthoDB; 5177934at2; -.
DR   Proteomes; UP000000428; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   PANTHER; PTHR43156:SF2; MULTIDOMAIN REGULATORY PROTEIN RV1364C; 1.
DR   PANTHER; PTHR43156; STAGE II SPORULATION PROTEIN E-RELATED; 1.
DR   Pfam; PF07228; SpoIIE; 1.
DR   SMART; SM00331; PP2C_SIG; 1.
DR   SUPFAM; SSF81606; PP2C-like; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000428};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        47..66
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        78..99
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          132..366
FT                   /note="PPM-type phosphatase"
FT                   /evidence="ECO:0000259|SMART:SM00331"
SQ   SEQUENCE   384 AA;  41243 MW;  9EF3BC0574F09D0E CRC64;
     MIRIKAGVPC GPRPRARPGE GFRAVVARGI PRDRMLRRRS RRESRRFRRA LSIALPTVWG
     TTAITYKLAC PLAQQNGLGA RIVTSAVFFA VGTGLILQVR HTLLRELRQA RKVAGAAQSV
     LLRPLPSRIG GLNIAAAQLS ADRGATVGGD LYEVIATEHG VRVVIGDVRG HGLAAIGTVA
     AVLGSFREAV HDEAELAGVL QRLERAMVRH LRERARAEPP SAGPDPDSLV AEEFVTVLLL
     EIRHDGEVYA LNCGHPWPYL LSGSRVELLA RAEPLPPLGP FPLPAELPST SCGPLQPGEA
     LFLHTDGAED ARDARGRFFP LAAVLGEVVR IPAVSPQAVL KAVFAGLLRH TGGRPSDDVA
     LLVLHNDPHR TSTTANHPMA HHVQ
//