ID   Q826L6_STRAW            Unreviewed;       794 AA.
AC   Q826L6;
DT   01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2003, sequence version 1.
DT   27-MAR-2024, entry version 119.
DE   SubName: Full=Magnesium or manganese-dependent protein phosphatase {ECO:0000313|EMBL:BAC74883.1};
GN   Name=prpJ7 {ECO:0000313|EMBL:BAC74883.1};
GN   ORFNames=SAVERM_7172 {ECO:0000313|EMBL:BAC74883.1};
OS   Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC
OS   14893 / NCIMB 12804 / NRRL 8165 / MA-4680).
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=227882 {ECO:0000313|EMBL:BAC74883.1, ECO:0000313|Proteomes:UP000000428};
RN   [1] {ECO:0000313|EMBL:BAC74883.1, ECO:0000313|Proteomes:UP000000428}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 /
RC   NRRL 8165 / MA-4680 {ECO:0000313|Proteomes:UP000000428};
RX   PubMed=11572948; DOI=10.1073/pnas.211433198;
RA   Omura S., Ikeda H., Ishikawa J., Hanamoto A., Takahashi C., Shinose M.,
RA   Takahashi Y., Horikawa H., Nakazawa H., Osonoe T., Kikuchi H., Shiba T.,
RA   Sakaki Y., Hattori M.;
RT   "Genome sequence of an industrial microorganism Streptomyces avermitilis:
RT   deducing the ability of producing secondary metabolites.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:12215-12220(2001).
RN   [2] {ECO:0000313|EMBL:BAC74883.1, ECO:0000313|Proteomes:UP000000428}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 /
RC   NRRL 8165 / MA-4680 {ECO:0000313|Proteomes:UP000000428};
RX   PubMed=12692562; DOI=10.1038/nbt820;
RA   Ikeda H., Ishikawa J., Hanamoto A., Shinose M., Kikuchi H., Shiba T.,
RA   Sakaki Y., Hattori M., Omura S.;
RT   "Complete genome sequence and comparative analysis of the industrial
RT   microorganism Streptomyces avermitilis.";
RL   Nat. Biotechnol. 21:526-531(2003).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BA000030; BAC74883.1; -; Genomic_DNA.
DR   RefSeq; WP_010988567.1; NZ_JZJK01000085.1.
DR   AlphaFoldDB; Q826L6; -.
DR   KEGG; sma:SAVERM_7172; -.
DR   eggNOG; COG2203; Bacteria.
DR   eggNOG; COG2208; Bacteria.
DR   HOGENOM; CLU_000445_43_3_11; -.
DR   OrthoDB; 118142at2; -.
DR   Proteomes; UP000000428; Chromosome.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd16936; HATPase_RsbW-like; 1.
DR   CDD; cd00130; PAS; 1.
DR   Gene3D; 3.30.450.40; -; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 2.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   InterPro; IPR003018; GAF.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013656; PAS_4.
DR   InterPro; IPR013767; PAS_fold.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   NCBIfam; TIGR00229; sensory_box; 1.
DR   PANTHER; PTHR43156:SF2; MULTIDOMAIN REGULATORY PROTEIN RV1364C; 1.
DR   PANTHER; PTHR43156; STAGE II SPORULATION PROTEIN E-RELATED; 1.
DR   Pfam; PF13185; GAF_2; 1.
DR   Pfam; PF13581; HATPase_c_2; 1.
DR   Pfam; PF00989; PAS; 1.
DR   Pfam; PF08448; PAS_4; 1.
DR   Pfam; PF07228; SpoIIE; 1.
DR   SMART; SM00065; GAF; 1.
DR   SMART; SM00331; PP2C_SIG; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   SUPFAM; SSF55781; GAF domain-like; 1.
DR   SUPFAM; SSF81606; PP2C-like; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR   PROSITE; PS50112; PAS; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000000428}.
FT   DOMAIN          25..63
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   REGION          302..367
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        332..349
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   794 AA;  85099 MW;  A4303FC27178EF3B CRC64;
     MDRFPHAADV DFHSPLDLSK AAAAVLDDEG RISGWGFSAQ RLLGHSPEDV LGKSATRLLA
     APSGQPTGQR LSALCKAHKP RSTVLDLCCR DGRTLRAAVT FSPLSDRGVA ATVVVAAEVE
     ALRSWEAQLA MLQGLATESS VGLTIFDSDM RVVWGNISTD LELGGVAQYT GRPAADLFPE
     GEFISRHHPP DEDQIMEHVL TTGEPIIGMH YRGRAPADPG REHVWSCSYH RMLDARGEPL
     GLFEESLDIT DRYRAQERLS LLVRAGKRIG ASLDVRRTAA EIADVAVPQL ADEVLVDLPP
     AVIEGRQPPT GSAPGHSLLR MHGRTPEGFR TSPVSYPPSS PQALSLATSR PVVDASPPEA
     PGGEGSAAPH SCLFVPLLTR DAILGLVTFR RSSNPDPFGP EEQTLAVELA ERAAVGIDNA
     RRYTSQHAAA LVLQRSLLPQ HLPEQSAVDV AYRYLPADSR VGVGGDWFDV IPLSGARVGL
     TVGDVVGHGV HAAATMGRLR ATVRTLALLD LDPAELLTRL DDLVAQDSDS HAEGGPIDEA
     LGVTCLYAIY DPVSSRCVWA SAGHPPPIVA DASGSVALSA LAPGPPLGLG GLPYENVELN
     LSSGSVVAFF TDGVVEDRRT DIDIGIDRLA QVLTWQRCPL EELCDRALSD MPPGPQADDA
     TLLLVRTRRL GADHVADLEL PPEPTMVAHA RTLTERQLAI WGLSELSFTA SLVVSELVTN
     GIRYATGPVM LRLIRDRCLL CEVSDNAHTA PHLRRARRDD EGGRGLFLVA QVSQRWGTRY
     TSSGKTIWAE LAIP
//