ID   Q825F4_STRAW            Unreviewed;       882 AA.
AC   Q825F4;
DT   01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2003, sequence version 1.
DT   27-MAR-2024, entry version 125.
DE   SubName: Full=Membrane translocator {ECO:0000313|EMBL:BAC75214.1};
GN   Name=amfT {ECO:0000313|EMBL:BAC75214.1};
GN   ORFNames=SAVERM_7503 {ECO:0000313|EMBL:BAC75214.1};
OS   Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC
OS   14893 / NCIMB 12804 / NRRL 8165 / MA-4680).
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=227882 {ECO:0000313|EMBL:BAC75214.1, ECO:0000313|Proteomes:UP000000428};
RN   [1] {ECO:0000313|EMBL:BAC75214.1, ECO:0000313|Proteomes:UP000000428}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 /
RC   NRRL 8165 / MA-4680 {ECO:0000313|Proteomes:UP000000428};
RX   PubMed=11572948; DOI=10.1073/pnas.211433198;
RA   Omura S., Ikeda H., Ishikawa J., Hanamoto A., Takahashi C., Shinose M.,
RA   Takahashi Y., Horikawa H., Nakazawa H., Osonoe T., Kikuchi H., Shiba T.,
RA   Sakaki Y., Hattori M.;
RT   "Genome sequence of an industrial microorganism Streptomyces avermitilis:
RT   deducing the ability of producing secondary metabolites.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:12215-12220(2001).
RN   [2] {ECO:0000313|EMBL:BAC75214.1, ECO:0000313|Proteomes:UP000000428}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 /
RC   NRRL 8165 / MA-4680 {ECO:0000313|Proteomes:UP000000428};
RX   PubMed=12692562; DOI=10.1038/nbt820;
RA   Ikeda H., Ishikawa J., Hanamoto A., Shinose M., Kikuchi H., Shiba T.,
RA   Sakaki Y., Hattori M., Omura S.;
RT   "Complete genome sequence and comparative analysis of the industrial
RT   microorganism Streptomyces avermitilis.";
RL   Nat. Biotechnol. 21:526-531(2003).
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DR   EMBL; BA000030; BAC75214.1; -; Genomic_DNA.
DR   RefSeq; WP_010988898.1; NZ_JZJK01000065.1.
DR   AlphaFoldDB; Q825F4; -.
DR   KEGG; sma:SAVERM_7503; -.
DR   eggNOG; COG0515; Bacteria.
DR   HOGENOM; CLU_014914_0_0_11; -.
DR   OrthoDB; 1492512at2; -.
DR   Proteomes; UP000000428; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR   GO; GO:0031179; P:peptide modification; IEA:InterPro.
DR   CDD; cd04791; LanC_SerThrkinase; 1.
DR   Gene3D; 1.50.10.20; -; 1.
DR   Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR007822; LANC-like.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   NCBIfam; NF038151; lanthi_synth_III; 1.
DR   Pfam; PF05147; LANC_like; 1.
DR   Pfam; PF00069; Pkinase; 1.
DR   PRINTS; PR01955; LANCFRANKIA.
DR   SMART; SM01260; LANC_like; 1.
DR   SMART; SM00220; S_TKc; 1.
DR   SUPFAM; SSF158745; LanC-like; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000000428}.
FT   DOMAIN          235..503
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50011"
FT   REGION          478..515
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        493..507
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   882 AA;  95748 MW;  59AC9A9C0C35F871 CRC64;
     MDKRYEVYAL ADRHFYETPD RLSVGASGAA PLYGPACREV PDGWRSARIG DWLTFTPVDD
     AGTALPGPAQ GWKIHASATR ANAERIATDV WEYCVPRRIP FKFVPGPHLL HLRNAKYAGR
     DTSGKFVTIY PADEEQLHLV LRELGERLDG CEGPYILTDL RWNDGPLYVR YGAFARSFVV
     DERGSLVPAV RDGEGTLVPD RRQPSFQVPE WVTLPAFLEP QLAARNTTTV GDLPYRIEKA
     LHFSNGGGVY AGTDTRDGRK VVLKEGRPHA GLASDGADAI ARLEREKYAL EQVSGLGVVP
     EVRDWFTLGD HRFLVMDFLE GRPLNSFFAE RHPLLTPDPE PDAVAAYTAW ALRIHRAVEQ
     AVHAVHARGI VFNDLHVFNI MVAPDEESVS LLDFEAAAPI EENGRQVVAH PGFFAPPDRT
     GPDVDRYALA CLRLALFLPV TTLFVVDRAK AAHLAEVVAG QFPDVPREFL DEAVAEITGR
     RQAPDPEGDK VSPSATSRPS PVRPTTSYTA PVDPGDWPYS RDSMVKAILA SATPERDDRL
     FPGDVAQFSD GGGLGLAHGA AGVLYVLEQT GADRYEEGER WLLDHTDPAP VGTPLGLYDG
     LAGVAYVLDL LGHRQRALDL VDGILRERWQ NLSSDLHGGL AGLGLVLGRL AHTTGETQLR
     ERAAEAARLL VRRLAEPRPA PPRRRAGLLR GASGIALFLL REYEETGAPE LRDAAAEALR
     QDLECCVVQK GGGLEVDEGW RTLPYLGDGS VGLGMVVDDF LALGGDDGHG TFEGARSGIL
     TAATSRFYAQ PGLFQGRAGM ILHLSRTSAP GATPERLAEQ VAGLGWFAMS YQGQLAFPGH
     QMMRLSMDLG TGTAGCLLAL GAALDGQTRA RLPFLPPLRG AH
//