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Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Chlamydophila caviae (strain GPIC)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate.UniRule annotation
Proteins known to be involved in the 5 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Phosphoglycerate kinase (pgk)
  3. 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (gpmA)
  4. Enolase (eno)
  5. Pyruvate kinase (pyk)
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei36SubstrateUniRule annotation1
Binding sitei119SubstrateUniRule annotation1
Binding sitei154SubstrateUniRule annotation1
Binding sitei207ATPUniRule annotation1
Binding sitei299ATP; via carbonyl oxygenUniRule annotation1
Binding sitei330ATPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi357 – 360ATPUniRule annotation4

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Transferase
Biological processGlycolysis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCCAV227941:G1G03-69-MONOMER
UniPathwayiUPA00109; UER00185

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinaseUniRule annotation (EC:2.7.2.3UniRule annotation)
Gene namesi
Name:pgkUniRule annotation
Ordered Locus Names:CCA_00061
OrganismiChlamydophila caviae (strain GPIC)
Taxonomic identifieri227941 [NCBI]
Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia
Proteomesi
  • UP000002193 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001459251 – 403Phosphoglycerate kinaseAdd BLAST403

Proteomic databases

PRIDEiQ824S8

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi227941.CCA00061

Structurei

3D structure databases

ProteinModelPortaliQ824S8
SMRiQ824S8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni21 – 23Substrate bindingUniRule annotation3
Regioni59 – 62Substrate bindingUniRule annotation4

Sequence similaritiesi

Belongs to the phosphoglycerate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105BZA Bacteria
COG0126 LUCA
KOiK00927
OMAiDMIFDIG
OrthoDBiPOG091H00YN

Family and domain databases

CDDicd00318 Phosphoglycerate_kinase, 1 hit
Gene3Di3.40.50.1260, 3 hits
HAMAPiMF_00145 Phosphoglyc_kinase, 1 hit
InterProiView protein in InterPro
IPR001576 Phosphoglycerate_kinase
IPR015911 Phosphoglycerate_kinase_CS
IPR015824 Phosphoglycerate_kinase_N
IPR036043 Phosphoglycerate_kinase_sf
PANTHERiPTHR11406 PTHR11406, 1 hit
PfamiView protein in Pfam
PF00162 PGK, 1 hit
PIRSFiPIRSF000724 Pgk, 1 hit
PRINTSiPR00477 PHGLYCKINASE
SUPFAMiSSF53748 SSF53748, 1 hit
PROSITEiView protein in PROSITE
PS00111 PGLYCERATE_KINASE, 1 hit

Sequencei

Sequence statusi: Complete.

Q824S8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDRLTVRELS PEENKVLVRV DFNVPIKDGK ILDDIRIRSA MPTINYLLQK
60 70 80 90 100
RAAVILMSHL GRPKGTGFEE KYSLQPVVEV LEGYLGHHVP LAPDCIGEVA
110 120 130 140 150
RQAVAQLSPG RVLLLENLRF HRGEEHPEED PTFAAELSSY GDFYVNDAFG
160 170 180 190 200
TSHRKHASVY HVPQAFPGRS AAGLLMEKEL EFLGQHLLHS PKRPFTAILG
210 220 230 240 250
GAKVSSKIGV IEALLSQVNN LLLAGGMGFT FLKALGKSVG NSLVEESGIE
260 270 280 290 300
LARRVLKLAE QRNVRIVLPI DVKVAKACEP GVSWSETLID QGIPADLEGL
310 320 330 340 350
DIGTKTIQEF CKIIDASATV FWNGPVGVYE VPPFDQGSMA IANCLARHSS
360 370 380 390 400
ATTVVGGGDA AAVVALAGCT SQVSHVSTGG GASLEFLENG FLPGTEVLSP

AQD
Length:403
Mass (Da):43,259
Last modified:June 1, 2003 - v1
Checksum:i873057426919099A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE015925 Genomic DNA Translation: AAP04813.1
RefSeqiWP_011006034.1, NC_003361.3

Genome annotation databases

EnsemblBacteriaiAAP04813; AAP04813; CCA_00061
KEGGicca:CCA_00061

Similar proteinsi

Entry informationi

Entry nameiPGK_CHLCV
AccessioniPrimary (citable) accession number: Q824S8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 25, 2003
Last sequence update: June 1, 2003
Last modified: May 23, 2018
This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

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