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Q824H4 (SYR_CHLCV) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:CCA_00172
OrganismChlamydophila caviae (strain GPIC) [Complete proteome] [HAMAP]
Taxonomic identifier227941 [NCBI]
Taxonomic lineageBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydophila

Protein attributes

Sequence length564 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 564564Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_0000151544

Regions

Motif124 – 13411"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q824H4 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: DA94DDA95C98A2B5

FASTA56463,453
        10         20         30         40         50         60 
MTMTLLSYLS SLCREATLSA FPQIDTFSPD ITQSTKEHFG HYQCNDAMKL ARTLKMAPRA 

        70         80         90        100        110        120 
IAEAIVNHIP KEIFTSIEIA GAGFINFTFS KEFLNNSLKT FSEELSSGFR VKDPKKVVID 

       130        140        150        160        170        180 
FSSPNIAKDM HVGHLRSTII GDCLARVFAF VGNDVSRLNH IGDWGTAFGM LITYLQEEPS 

       190        200        210        220        230        240 
EDIENLEDLT VLYKKAHARF AEDAEFKKRS QTNVVALQAG DPSALKLWKQ ICAISERAFQ 

       250        260        270        280        290        300 
KIYNILDIAI EKRGESFYNP FLPEIIQDLE NKNLITISDN AKCVFHEGFS IPLMVQKSDG 

       310        320        330        340        350        360 
GYNYATTDLA AMRYRVNNDG ADKIIIVTDM GQSLHFQLLE ATALAAGYLP NKETFSHVGF 

       370        380        390        400        410        420 
GLVLDSEGKK FKTRSGENIK LKELLDTAID QAKATLKEHR PEISDEEISS RAPILGINAI 

       430        440        450        460        470        480 
KYADLSSHRV SDYIFSFEKM LRFEGNTAMF LLYAYVRIQG IKRRLGIETL DLEATPNIQE 

       490        500        510        520        530        540 
PSEEALALAL LRFPEAIDLT LKDLCPHFLT DYLYMLTNKF NAFFRDCHIE GSSHQKERLY 

       550        560 
LCALVEKTLA AGMHLLGLQT LDKL 

« Hide

References

[1]"Genome sequence of Chlamydophila caviae (Chlamydia psittaci GPIC): examining the role of niche-specific genes in the evolution of the Chlamydiaceae."
Read T.D., Myers G.S.A., Brunham R.C., Nelson W.C., Paulsen I.T., Heidelberg J.F., Holtzapple E.K., Khouri H.M., Federova N.B., Carty H.A., Umayam L.A., Haft D.H., Peterson J.D., Beanan M.J., White O., Salzberg S.L., Hsia R.-C., McClarty G. expand/collapse author list , Rank R.G., Bavoil P.M., Fraser C.M.
Nucleic Acids Res. 31:2134-2147(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: GPIC.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE015925 Genomic DNA. Translation: AAP04923.1.
RefSeqNP_829045.1. NC_003361.3.

3D structure databases

ProteinModelPortalQ824H4.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING227941.CCA00172.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAP04923; AAP04923; CCA_00172.
GeneID1217857.
KEGGcca:CCA00172.
PATRIC20269358. VBIChlCav107360_0179.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
KOK01887.
OMAPDITKAW.
OrthoDBEOG6JB13C.
ProtClustDBPRK01611.

Enzyme and pathway databases

BioCycCCAV227941:GH8L-184-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_CHLCV
AccessionPrimary (citable) accession number: Q824H4
Entry history
Integrated into UniProtKB/Swiss-Prot: July 25, 2003
Last sequence update: June 1, 2003
Last modified: April 16, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries