Q823P0 (DNAA1_CHLCV) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Chromosomal replication initiator protein DnaA 1

Gene names

Name:	dnaA1
Synonyms:	dnaA-1
Ordered Locus Names:	CCA_00368

Organism

Chlamydophila caviae [Complete proteome] [HAMAP]

Taxonomic identifier

83557 [NCBI]

Taxonomic lineage

Bacteria › Chlamydiae › Chlamydiales › Chlamydiaceae › Chlamydia/Chlamydophila group › Chlamydophila

Protein attributes

Sequence length	450 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids By similarity. HAMAP MF_00377
Subcellular location	Cytoplasm By similarity HAMAP MF_00377.
Sequence similarities	Belongs to the DnaA family.

Ontologies

Keywords
Biological process	DNA replication
Cellular component	Cytoplasm
Ligand	ATP-binding DNA-binding Nucleotide-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA-dependent DNA replication initiation Inferred from electronic annotation. Source: InterPro regulation of DNA replication Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW DNA replication origin binding Inferred from electronic annotation. Source: InterPro nucleoside-triphosphatase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 450	450	Chromosomal replication initiator protein DnaA 1 HAMAP MF_00377		PRO_0000114155
Regions
	Nucleotide binding	156 – 163	8	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	Q823P0 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: CF440A7B300210D8	FASTA	450	51,100
	10 20 30 40 50 60 MLTCSDCSTW EQFVNYVKTR CSKTAFENWI SPIQIIEETQ EKIRLEVPNI FVQNYLLDNY 70 80 90 100 110 120 KQDLCSFVPL DAQGEPALEF VVAEIKKAPA QPIAPREPQE SPAETFEESK DFELKLNAAY 130 140 150 160 170 180 RFDNFIEGPS NQFVKSAAVG IAGRPGRSYN PLFIHGGVGL GKTHLLHAVG HYVREHHKNL 190 200 210 220 230 240 RVHCITTEAF INDLVQHLRL KSIDKMKNFY RSLDLLLVDD IQFLQNRQNF EEEFCNTFET 250 260 270 280 290 300 LINLNKQIVI TSDKPPGQLK LSERIIARME WGLVAHVGIP DLETRVAILQ HKAEQKGLHI 310 320 330 340 350 360 PNEIAFYIAD HIYGNVRQLE GAINKLTAYC RLFGKTLTES IVRDTLRELF RSPSKQKVSV 370 380 390 400 410 420 ESILKSVATV FQVKLQDLKG TSRSKELVLA RQVAMYLAKT LITDSLVAIG SAFGKTHSTV 430 440 450 LYACKTIEQK IEKDETLTRQ ISLCKNHIVG

References

[1]

"Genome sequence of Chlamydophila caviae (Chlamydia psittaci GPIC): examining the role of niche-specific genes in the evolution of the Chlamydiaceae." Read T.D., Myers G.S.A., Brunham R.C., Nelson W.C., Paulsen I.T., Heidelberg J.F., Holtzapple E.K., Khouri H.M., Federova N.B., Carty H.A., Umayam L.A., Haft D.H., Peterson J.D., Beanan M.J., White O., Salzberg S.L., Hsia R.-C., McClarty G. , Rank R.G., Bavoil P.M., Fraser C.M. Nucleic Acids Res. 31:2134-2147(2003) [PubMed: 12682364] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: GPIC.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE015925 Genomic DNA. Translation: AAP05115.1.
RefSeq	NP_829237.1. NC_003361.3.
3D structure databases
ProteinModelPortal	Q823P0.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1218053.
GenomeReviews	Gene locus CCA_00368 in contig AE015925_GR.
KEGG	cca:CCA00368.
PATRIC	20269798. VBIChlCav107360_0397.
TIGR	CCA_00368.
Phylogenomic databases
HOGENOM	HBG695666.
OMA	CHTLNAL.
PhylomeDB	Q823P0.
ProtClustDB	PRK00149.
Enzyme and pathway databases
BioCyc	CCAV227941:CCA_00368-MONOMER.
Family and domain databases
HAMAP	MF_00377. DnaA_bact. [Tree]
InterPro	IPR003593. ATPase_AAA+_core. IPR001957. Chromosome_initiator_DnaA. IPR020591. Chromosome_initiator_DnaA-like. IPR018312. Chromosome_initiator_DnaA_CS. IPR013159. DnaA_C. IPR013317. DnaA_Hda. IPR010921. Trp_repressor/repl_initiator. [Graphical view]
Gene3D	G3DSA:1.10.1750.10. DnaA_C. 1 hit.
KO	K02313.
Pfam	PF00308. Bac_DnaA. 1 hit. PF08299. Bac_DnaA_C. 1 hit. [Graphical view]
PRINTS	PR00051. DNAA.
SMART	SM00382. AAA. 1 hit. SM00760. Bac_DnaA_C. 1 hit. [Graphical view]
SUPFAM	SSF48295. Trp_repress_rep. 1 hit.
TIGRFAMs	TIGR00362. DnaA. 1 hit.
PROSITE	PS01008. DNAA. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

DNAA1_CHLCV

Accession

Primary (citable) accession number: Q823P0

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 25, 2003
Last sequence update:	June 1, 2003
Last modified:	January 25, 2012
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program