Reviewed, UniProtKB/Swiss-Prot Q823K6 (DCD_CHLCV)

Names and origin

Protein names

Recommended name:
    Deoxycytidine triphosphate deaminase
      Short name=dCTP deaminase
    EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	CCA_00404

Organism

Chlamydophila caviae [Complete proteome] [HAMAP]

Taxonomic identifier

83557 [NCBI]

Taxonomic lineage

Bacteria › Chlamydiae › Chlamydiales › Chlamydiaceae › Chlamydophila

Protein attributes

Sequence length	190 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro pyrimidine ribonucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	dCTP deaminase activity Inferred from electronic annotation. Source: HAMAP protein binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 190	190	Deoxycytidine triphosphate deaminase HAMAP MF_00146		PRO_0000155974

Sequences

	Sequence		Length	Mass (Da)
	Q823K6-1 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: BA028A4802BF5B44	FASTA	190	21,546
	10 20 30 40 50 60 MSIKEDKWIR KMALAHGMIE PFADGQVNVD AETGEKLISY GLSSYGYDLR LSREFKVFTN 70 80 90 100 110 120 VYNSLVDPKH FTEDTFISIT DDVCIIPPNS FALAHSVEYF RIPRNILTMC IGKSTYARCG 130 140 150 160 170 180 LIVNVTPFEP EWEGYVTIEI SNTTPLPAKI YANEGIAQVL FFEADEMCEV SYAERKGKYQ 190 KQQGITVPFV

References

[1]

"Genome sequence of Chlamydophila caviae (Chlamydia psittaci GPIC): examining the role of niche-specific genes in the evolution of the Chlamydiaceae." Read T.D., Myers G.S.A., Brunham R.C., Nelson W.C., Paulsen I.T., Heidelberg J.F., Holtzapple E.K., Khouri H.M., Federova N.B., Carty H.A., Umayam L.A., Haft D.H., Peterson J.D., Beanan M.J., White O., Salzberg S.L., Hsia R.-C., McClarty G. , Rank R.G., Bavoil P.M., Fraser C.M. Nucleic Acids Res. 31:2134-2147(2003) [PubMed: 12682364] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: GPIC.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE015925 Genomic DNA. Translation: AAP05150.1.
RefSeq	NP_829272.1.
3D structure databases
SMR	Q823K6. Positions 3-188.
ModBase	Search...
Genome annotation databases
GeneID	1218089.
GenomeReviews	Gene locus CCA_00404 in contig AE015925_GR.
KEGG	cca:CCA00404.
TIGR	CCA_00404.
Phylogenomic databases
HOGENOM	HBG553199.
OMA	MEYFRIP.
PhylomeDB	Q823K6.
Enzyme and pathway databases
BioCyc	CCAV227941:CCA_00404-MONOMER.
BRENDA	3.5.4.13. 304519.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase. [Tree]
InterPro	IPR011962. dCTP_deam. IPR008180. DeoxyUTP_pyroPase_dom. [Graphical view]
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
TIGRFAMs	TIGR02274. dCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_CHLCV

Accession

Primary (citable) accession number: Q823K6

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 25, 2003
Last sequence update:	June 1, 2003
Last modified:	February 9, 2010
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)