Reviewed, UniProtKB/Swiss-Prot Q823A6 (SURE1_CHLCV)

Names and origin

Protein names

Recommended name:
    5'-nucleotidase surE 1
    EC=3.1.3.5
Alternative name(s):
    Nucleoside 5'-monophosphate phosphohydrolase 1

Gene names

Name:	surE1
Ordered Locus Names:	CCA_00520

Organism

Chlamydophila caviae [Complete proteome] [HAMAP]

Taxonomic identifier

83557 [NCBI]

Taxonomic lineage

Bacteria › Chlamydiae › Chlamydiales › Chlamydiaceae › Chlamydophila

Protein attributes

Sequence length	279 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates By similarity. HAMAP MF_00060
Catalytic activity	A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate. HAMAP MF_00060
Cofactor	Binds 1 divalent metal cation per subunit By similarity. HAMAP MF_00060
Subcellular location	Cytoplasm Potential HAMAP MF_00060.
Sequence similarities	Belongs to the surE nucleotidase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	Metal-binding Nucleotide-binding
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	5'-nucleotidase activity Inferred from electronic annotation. Source: HAMAP metal ion binding Inferred from electronic annotation. Source: HAMAP nucleotide binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 279	279	5'-nucleotidase surE 1 HAMAP MF_00060		PRO_0000111799
Sites
	Metal binding	12	1	Divalent metal cation By similarity
	Metal binding	13	1	Divalent metal cation By similarity
	Metal binding	45	1	Divalent metal cation By similarity
	Metal binding	103	1	Divalent metal cation By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q823A6-1 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: EE532E1C3EF18C4D	FASTA	279	30,457
	10 20 30 40 50 60 MSKRLKILLT NDDGISAKGM SLLVSNLLKA DFADLYVVAP STEQSGKSMS FSYTQPVSIE 70 80 90 100 110 120 SVDYPQEVAG AWAVSGSPVD CVKLALGDLF YDSFPDLVLS GINHGSNAGR NIFYSGTAGA 130 140 150 160 170 180 AMEAILSGVP SIAFSQEQHI SFFQTDSAPE LLRKLSFYAL SNPFPVVTGF NVNFPASERN 190 200 210 220 230 240 EPWKGMRLVA TGKEFACGLP KLLSSDGKRK SFSLSDCQVV MDEDISEECR CLLDNYITVV 250 260 270 PLLVRNSPLA LTSESEFQQL QETFQEFMCS EADTRLFDV

References

[1]

"Genome sequence of Chlamydophila caviae (Chlamydia psittaci GPIC): examining the role of niche-specific genes in the evolution of the Chlamydiaceae." Read T.D., Myers G.S.A., Brunham R.C., Nelson W.C., Paulsen I.T., Heidelberg J.F., Holtzapple E.K., Khouri H.M., Federova N.B., Carty H.A., Umayam L.A., Haft D.H., Peterson J.D., Beanan M.J., White O., Salzberg S.L., Hsia R.-C., McClarty G. , Rank R.G., Bavoil P.M., Fraser C.M. Nucleic Acids Res. 31:2134-2147(2003) [PubMed: 12682364] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: GPIC.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE015925 Genomic DNA. Translation: AAP05263.1.
RefSeq	NP_829385.1.
3D structure databases
SMR	Q823A6. Positions 6-264.
ModBase	Search...
Genome annotation databases
GeneID	1218205.
GenomeReviews	Gene locus CCA_00520 in contig AE015925_GR.
KEGG	cca:CCA00520.
TIGR	CCA_00520.
Phylogenomic databases
HOGENOM	HBG600532.
OMA	SNAGRNI.
PhylomeDB	Q823A6.
Enzyme and pathway databases
BioCyc	CCAV227941:CCA_00520-MONOMER.
BRENDA	3.1.3.5. 304519.
Family and domain databases
HAMAP	MF_00060. SurE. [Tree]
InterPro	IPR002828. SurE-like_Pase/nucleotidase. [Graphical view]
Gene3D	G3DSA:3.40.1210.10. SurE-like_Pase/nucleotidase. 1 hit.
Pfam	PF01975. SurE. 1 hit. [Graphical view]
TIGRFAMs	TIGR00087. surE. 1 hit.
ProtoNet	Search...

Entry information

Entry name

SURE1_CHLCV

Accession

Primary (citable) accession number: Q823A6

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 25, 2003
Last sequence update:	June 1, 2003
Last modified:	February 9, 2010
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)