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Q822R1 (PKN1_CHLCV) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 70. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Serine/threonine-protein kinase pkn1

EC=2.7.11.1
Gene names
Name:pkn1
Ordered Locus Names:CCA_00618
OrganismChlamydophila caviae (strain GPIC) [Complete proteome] [HAMAP]
Taxonomic identifier227941 [NCBI]
Taxonomic lineageBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydophila

Protein attributes

Sequence length618 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Together with the serine/threonine kinase PknD, may play a role in the specific interactions with host proteins during intracellular growth By similarity.

Catalytic activity

ATP + a protein = ADP + a phosphoprotein.

Post-translational modification

Autophosphorylated on serine and threonine residues By similarity.

Sequence similarities

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

Contains 1 protein kinase domain.

Caution

Gly-141 is present instead of the conserved Asp which is expected to be an active site residue.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 618618Serine/threonine-protein kinase pkn1
PRO_0000171186

Regions

Domain15 – 381367Protein kinase
Nucleotide binding21 – 299ATP By similarity

Sites

Binding site441ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q822R1 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: 0D0003F43DA35F79

FASTA61870,173
        10         20         30         40         50         60 
MEGEQDIGVE FLGDYKILCY LRKGLWCQDI LAEHRFIKKR YILKLLCSEL SSSEAFMTAF 

        70         80         90        100        110        120 
HEAIIKLATI RHPGIISIEN VSQAEGQYFL VTEEKEVPTL SLAQYLSSCS QGLSELEAKD 

       130        140        150        160        170        180 
LICQLAEILD YAHANRLIHG GLSLDSVHID LTGQSPKVFL PELGFSFLLK DQYTQSLLRD 

       190        200        210        220        230        240 
SSEKSSFDKL KQILLFQAPE TALGTVAEDV YAFGVIVYFL LFRQLPQGAF PLPSEAFPEY 

       250        260        270        280        290        300 
VYDWDRLIQS CLSYAVEKRP KKLAPLLVKK TLGEQFLAAK IQCSEEDLRE IEEEPQVPSV 

       310        320        330        340        350        360 
ANILQKVEDK IIEETSDHLE FVLVEAKSID EAMNTSVDSK EEVVAEDESY SNALQSLLIR 

       370        380        390        400        410        420 
EPVVSRYVEE EKEEVKPQPL FTEMVFIEGG KFLRGSREGQ RDEHPVHEIF LHSFFLDIHP 

       430        440        450        460        470        480 
VTNEQFVRYL ECSGSEQDKY YNELIRLKDS RIQRRSGKLV IEPGYAKHPV VGVTWYGASG 

       490        500        510        520        530        540 
YASWVGKRLP TEAEWEIASC GGVTQLRYPC GEEIDKSQAN FFSSDTTPVM SYPANPYGLY 

       550        560        570        580        590        600 
DMAGNVYEWC EDWYGYDFYE ISAQESHAPQ GPAQGVYRVL RGGCWKSLKD DLRCAHRHRN 

       610 
NPGAVNSTYG FRCAKGVK 

« Hide

References

[1]"Genome sequence of Chlamydophila caviae (Chlamydia psittaci GPIC): examining the role of niche-specific genes in the evolution of the Chlamydiaceae."
Read T.D., Myers G.S.A., Brunham R.C., Nelson W.C., Paulsen I.T., Heidelberg J.F., Holtzapple E.K., Khouri H.M., Federova N.B., Carty H.A., Umayam L.A., Haft D.H., Peterson J.D., Beanan M.J., White O., Salzberg S.L., Hsia R.-C., McClarty G. expand/collapse author list , Rank R.G., Bavoil P.M., Fraser C.M.
Nucleic Acids Res. 31:2134-2147(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: GPIC.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE015925 Genomic DNA. Translation: AAP05360.1.
RefSeqNP_829482.1. NC_003361.3.

3D structure databases

ProteinModelPortalQ822R1.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING227941.CCA00618.

Proteomic databases

PRIDEQ822R1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAP05360; AAP05360; CCA_00618.
GeneID1218303.
KEGGcca:CCA00618.
PATRIC20270351. VBIChlCav107360_0663.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0515.
OMAIDKSQAN.
OrthoDBEOG622PMB.

Enzyme and pathway databases

BioCycCCAV227941:GH8L-643-MONOMER.

Family and domain databases

Gene3D3.90.1580.10. 1 hit.
InterProIPR016187. C-type_lectin_fold.
IPR005532. FGE_dom.
IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
[Graphical view]
PfamPF03781. FGE-sulfatase. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMSSF56112. SSF56112. 1 hit.
SSF56436. SSF56436. 1 hit.
PROSITEPS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePKN1_CHLCV
AccessionPrimary (citable) accession number: Q822R1
Entry history
Integrated into UniProtKB/Swiss-Prot: November 9, 2004
Last sequence update: June 1, 2003
Last modified: May 14, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families